Graish, M.S.Ali, A.B.M.Al-Zahiwat, M.M.Alardhi, S.M.Baghoolizadeh, M.Salahshour, S.Pirmoradian, M.2025-04-162025-04-1620252666-016410.1016/j.cscee.2025.1011802-s2.0-86000578778https://doi.org/10.1016/j.cscee.2025.101180https://hdl.handle.net/20.500.14517/7812Viscosity is a crucial parameter for heat transfer systems, governing pumping power, Rayleigh number, and Reynolds number; thus, viscosity prediction for hybrid nanofluids is important. Although some studies have employed ML algorithms for predicting viscosity, limited ML algorithms or specific nanofluid types were examined in previous studies, disregarding the complexities involved in the rheological behavior of a complex nanofluid system such as non-Newtonian hybrid nanofluids. To overcome this limitation, this study offers a practical contribution by utilizing 20 different machine-learning models to predict the viscosity of iron-CuO/water-ethylene glycol non-Newtonian hybrid nanofluids. The influences of the input variables: solid volume fraction (SVF), temperature, and shear rate on viscosity prediction are systematically assessed. We evaluate the prediction accuracy and reliability of algorithms using ten performance metrics including RMSE, MAE, R2 and NSE. Multivariate Polynomial Regression (MPR) outperforms the other algorithms, which is evident in the highest correlation coefficient (R2 = 0.992) and lowest error metrics. At the other end, is the Extreme Learning Machine (ELM), which turns out to be the worst performer. A unique contribution of this paper is that we extract a mathematical equation from the MPR model that allows for straightforward calculation of viscosity, avoiding non-trivial ML computations. This simplicity aids in practical applications and increases usefulness for engineers and researchers alike. Using advanced data visualization techniques (heatmaps, box plots, KDE plots and Taylor diagrams), the relationships between input variables and viscosity as well as the model performance are explored. These results give a better understanding of the non-Newtonian hybrid nanofluid behavior and a solid predictor of design-efficient heat transfer systems. © 2025 The Authorseninfo:eu-repo/semantics/openAccessMachine Learning AlgorithmsNon-Newtonian Hybrid Nano- AntifreezeViscosityArticleN/AQ111