Ates, Ayfer AtavArican, BurcinCiftcioglu, ElifKucukay, E. SedatEndodonti / Endodontics2024-05-252024-05-25202160268-89211435-604X10.1007/s10103-021-03356-42-s2.0-85108274011https://doi.org/10.1007/s10103-021-03356-4https://hdl.handle.net/20.500.14517/1632Ciftcioglu, Elif/0000-0002-2578-0168; Arican, Burcin/0000-0001-5757-0571This study aims to assess the efficacy of various irrigation protocols on the dentinal tubule penetration of a bioceramic-based endodontic sealer. Sixty-four single-rooted extracted human mandibular incisors were used. After instrumentation, teeth were randomly divided into the following four groups (n = 16 each) according to the final irrigation technique: group 1, conventional endodontic needle (CEN); group 2, EndoActivator (EA); group 3, Er,Cr: YSGG laser; group 4, XP-endo Finisher (XPF). The root canals were finally irrigated with 17% EDTA and 5.25% NaOCl for 1 min (min) respectively. The teeth were then obturated with Endosequence BC Points and rhodamine B dye-labeled BC Sealer. After 2 weeks, 1-mm-thick transverse sections were cut 2 and 5 mm from the apex, and examined by confocal laser scanning microscopy at 5 x magnification. The total percentage of sealer penetration (TPSP), sealer penetration area (SPA), and maximum sealer penetration depth (MSPD) was measured. Data were analyzed by Kruskal-Wallis, Dunn's multiple comparison, and Wilcoxon tests, with significance set at P < 0.05. At 2 mm level, no significant differences were detected among the groups (P > 0.05). At the 5 mm level, the XPF group showed significantly higher values for both TPSP and SPA in comparison with the Er,Cr: YSGG laser and CEN groups (P < 0.05), but no significant difference was observed with the EA group. The choice of different final irrigation techniques can affect dentinal tubule penetration.eninfo:eu-repo/semantics/closedAccessBioceramic sealerEr,Cr:YSGGEndoActivatorSealer penetrationXP-endo FinisherArticleQ2Q136817711777WOS:00066351280000134148161