PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14517/21

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Citation Count: 21
Accuracy of single implant scans with a combined healing abutment-scan body system and different intraoral scanners: An in vitro study
(Elsevier Sci Ltd, 2021) Cakmak, Gulce; Donmez, Mustafa Borga; Atalay, Sevda; Yilmaz, Hakan; Kokat, Ali Murat; Yilmaz, Burak
Objective: The aim of the present study was to evaluate the accuracy of single implant scans with a combined healing abutment-scan body (CHA-SB) system using different intraoral scanners. Methods: A partially edentulous model with an implant was fabricated, and a CHA-SB system was secured on the implant. The model was scanned using an industrial-grade blue light scanner (ATOS Core 80) and a master reference model was generated (MRM). The model was also scanned with 4 different intraoral scanners (IOSs) [(Virtuo Vivo (VV), TRIOS 3 (T3), Omnicam (CO), and Primescan (PS)]. Test scans (n = 8) were superimposed over the MRM using the best fit algorithm (GOM Inspect 2018; GOM GmbH). After superimpositions, distance and angular deviations at selected areas on CHA-SB system were calculated. The data were analyzed with a 1way ANOVA and Tukey HSD tests for trueness and precision (alpha=0.05). Results: The differences in trueness (distance deviations) among tested IOSs were nonsignificant (P=.652). VV presented the highest angular deviations (P <=.031), and the angular deviations in other IOS scans were not found different (P >=.378). The precision of distance deviation data was not significantly different among scanners (P=.052). For the precision of angular deviation data, significant differences were found among IOSs (P=.002). Compared with PS (P=.007) and T3 (P=.014), VV had significantly lower precision, which was not significantly different than that of CO (P=.815). Conclusions: The accuracy (angular deviation) of scans of a combined healing abutment-scan body system on a single implant varied depending on the IOS. VirtuoVivo scans had the lowest accuracy in terms of angular deviations. When the distance deviation data were considered, scan accuracy of scanners was similar. Clinical Significance: A recently introduced combined healing abutment-scan body system combines the acquisition of both the implant and the soft tissue. When different intraoral scanners scan the combined healing abutment-scan body system, the scan accuracy may vary.
Citation Count: 0
Acute spinal epidural hematoma: A case report and review of the literature
(Turkish Assoc Trauma Emergency Surgery, 2020) Akar, Ezgi; Ogrenci, Ahmet; Koban, Orkun; Yilmaz, Mesut; Dalbayrak, Sedat
Spinal epidural hematoma (SEH) is a rare but a significant cause of spinal cord compression and neurologic deficits. Its etiology is usually unknown and requires emergency intervention. The present study aims to review the clinical significance, treatment strategies and clinical outcomes of traumatic SEH with a rare case presentation. Our patient was a 42-year-old female who presented with back pain and loss of sensation and strength in the legs. The patient did not have any disease and did not use anticoagulant drugs. The patient developed numbness in her legs half an hour after having a traditional back walking massage due to occasional back pain. She was paraplegic and anesthetic when seen in our clinic. Thoracic computed tomography (CT) and magnetic resonance imaging (MRI) revealed posterior epidural hemorrhage at Th3-Th4 levels. In the 12th hour, the hematoma was evacuated by an emergency decompressive hemilaminectomy. At the postoperative 24th hour, the patient had symptomatic improvement, and in the sixth month, the patient was mobilized with support. SEH is a rare condition that should be considered in patients with sudden onset of back pain and extremity weakness. Although the gold standard diagnostic tool is MRI, CT is often sufficient to avoid delayed surgery. Immediate surgical decompression (laminectomy/hemilaminectomy) should be performed in cases diagnosed with SEH with neurological deficits.
Citation Count: 0
Addendum to Spinal Schwannomatosis: Case Report of a Rare Condition
(Turkish Neurosurgical Soc, 2017) Hakan, Tayfun; Celikoglu, Erhan; Aker, Fugen; Barisik, Nagehan
[No Abstract Available]
Citation Count: 0
Addressing urinary incontinence by gender: a nationwide population-based study in Turkiye
(Bmc, 2023) Yavuz, Melike; Etiler, Nilay
BackgroundUrinary incontinence (UI), which usually occurs in women but affects both sexes, is a significant public health challenge. This study aims to comprehensively investigate the prevalence and determinants of UI in men and women, considering gender-specific factors.MethodsThe study performed a secondary analysis on data obtained from 13,383 individuals surveyed in the 2019 Turkish Health Survey, providing a representation of the Turkish population. The dataset included sociodemographic and health-related variables like UI, body mass index (BMI), physical activity, smoking, and chronic diseases-statistical analysis employed chi-square tests and gender-stratified logistic regression models to identify UI-associated factors.ResultsOur results showed that UI affected 8.8% of the population, with a striking gender disparity. Women had a notably higher prevalence at 11.2%, while men had a lower rate of 5.5%. Importantly, this gender gap narrowed with age. For example, in the 34-44 age group, the female/male ratio was 6.9, but it decreased to 1.4 in the 65-74 age group. Marital status and employment status played significant roles. Separated, divorced, or widowed individuals, particularly women, had the highest prevalence at 19.3%. Employment status influenced UI prevalence, with employed men having the lowest rate (2.1%), while retired women faced the highest rate (15.0%). Higher BMI, especially in obese individuals, significantly raised UI prevalence, reaching 7.9% for men and 15.8% for women. Physical inactivity, notably in women (17.0%), and prolonged sedentary hours (13.9%) were associated with higher UI rates. Former smokers, especially women (15.9%), had a notable impact on UI. Poor perceived health and chronic conditions like Chronic Obstructive Pulmonary Disease (COPD), hypertension, and diabetes were significantly associated with higher UI prevalence. Logistic regression analysis revealed that age, education, perceived health status, COPD, and diabetes were significant factors associated with UI in both sexes, while in women, BMI, physical activity, and smoking also played notable roles.ConclusionsThis extensive UI study has unveiled notable gender disparities and determinants. Notably, these disparities decrease with age, underlining UI's changing nature over time. Modifiable factors impact women more, while non-modifiable factors are linked to men. The study underscores the importance of tailoring healthcare strategies to address UI based on gender.
Citation Count: 9
Adherence to guideline-directed medical and device Therapy in outpAtients with heart failure with reduced ejection fraction: The ATA study
(Turkish Soc Cardiology, 2020) Kocabas, Umut; Kivrak, Tarik; Oztekin, Gulsum Meral Yilmaz; Tanik, Veysel Ozan; Ozdemir, Ibrahim Halil; Kaya, Ersin; Pehlivanoglu, Seckin
Objective: Despite recommendations from heart failure guidelines on the use of pharmacologic and device therapy in patients with heart failure with reduced ejection fraction (HFrEF), important inconsistencies in guideline adherence persist in practice. The aim of this study was to assess adherence to guideline-directed medical and device therapy for the treatment of patients with chronic HFrEF (left ventricular ejection fraction <= 40%). Methods: The Adherence to guideline-directed medical and device Therapy in outpAtients with HFrEF (ATA) study is a prospective, multicenter, observational study conducted in 24 centers from January 2019 to June 2019. Results: The study included 1462 outpatients (male: 70.1%, mean age: 67 +/- 11 years, mean LVEF: 30%+/- 6%) with chronic HFrEF. Renin-angiotensin system (RAS) inhibitors, beta-blockers, mineralocorticoid receptor antagonists (MRAs), and ivabradin were used in 78.2%, 90.2%, 55.4%, and 12.1% of patients, respectively. The proportion of patients receiving target doses of medical treatments was 24.6% for RAS inhibitors, 9.9% for beta-blockers, and 10.5% for MRAs. Among patients who met the criteria for implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy (CRT), only 16.9% of patients received an ICD (167 of 983) and 34% (95 of 279) of patients underwent CRT (95 of 279). Conclusion: The ATA study shows that most HFrEF outpatients receive RAS inhibitors and beta-blockers but not MRAs or ivabradin when the medical reasons for nonuse, such as drug intolerance or contraindications, are taken into account. In addition, most eligible patients with HFrEF do not receive target doses of pharmacological treatments or guideline-recommended device therapy.
Citation Count: 7
Adjacent Segment Disease (ASD) in Incidental Segmental Fused Vertebra and Comparison With the Effect of Stabilization Systems on ASD
(Springernature, 2021) Hekimoglu, Mehdi; Basak, Ahmet; Yilmaz, Atilla; Yildirim, Hakan; Aydin, Ahmet Levent; Karadag, Kursat; ozer, Ali Fahir
Objective Adjacent segment disease is a controversial process after spine stabilization. The two important factors discussed are natural aging and hypermobility in incidental segmental fusion anomalies; patients have two or more fused vertebrae from birth, which are the results of spinal movement restriction due to the fusion of some spinal units. This article's main purpose is to determine the degree of relationship of hypermobility and the aging process in the deterioration of the disks adjacent to fusion. Methods In this study, the degenerative process developed by hypermobility in the adjacent segment due to incidental segmental fusion was evaluated. The MRI images of 52 adjacent and nonadjacent disks of 45 patients in total were analyzed according to the Pfirrmann grading systems. The average Pfirrmann rating of the disks just above and below the fused segment and the distant first, second, and third non-neighboring levels were evaluated and calculated, respectively. Results The highest rate of incidental fusion is determined on the cervical area with 51.9%, followed by the thoracal area with 32.7%, and the lumbar area with 15.4%. Damage to the adjacent segment disks in cases with incidental fusion can still be seen at any age, with fusion, indicating that the hypermobility effect plays a more prominent role. The evidence of hypermobility without aging is that the segments adjacent to fusion undergo more degeneration than the distant disks. Conclusion Adjacent segment disease is under the influence of many factors. Our findings suggest that its incidence is increasing with the pathological processes initiated by hypermobility. It seems that, at least, it carries equal importance as compared to age. Fusion surgeries damage the adjacent segments under the influence of the passage of time beyond the physiological aging of the patient.
Citation Count: 8
Airborne pathogen projection during ophthalmic examination
(Springer, 2020) Bostanci Ceran, Basak; Karakoc, Alp; Taciroglu, Ertugrul
Purpose Microscale droplets act as coronaviruses (CoV) carriers in the air when released from an infected person and may infect others during close contact such as ophthalmic examination. The main objective of the present work is to demonstrate how CoV deposited droplets are projected during biomicroscopy and to discuss what kind of precautions should be taken in ophthalmic practice. Methods A coupled fluid-structure system comprising smoothed particle hydrodynamics and the finite element method has been built to assess the projection of droplets spreading from an infected person. Different conditions based on the maximum exit flow velocity from the infector's mouth during the ophthalmic examination were modeled. Results During exhalation, for which the exit flow is similar to 1000 mm/s, the average horizontal distance of the flow front was similar to 200 mm while individual particles can reach up to similar to 500 mm. In case of coughing or sneezing (corresponding to an exit flow of similar to 12,000 mm/s), the average horizontal distance of the flow front was similar to 1300 mm. Conclusion During the ophthalmic examination, the proximity to the patient's nose and mouth was observed to be less than the horizontal distance of flow front particles. Even though mounted breath shields are used, particles flew beyond the shield and contaminate the ophthalmologist. Compared with the current protective breath shields, the use of a larger shield with a minimum radius of 18 cm is needed to decrease viral transmission.
Citation Count: 1
Amine-functionalized mesoporous silica nanoparticles decorated by silver nanoparticles for delivery of doxorubicin in breast and cervical cancer cells
(Elsevier, 2024) Ghobadi, Melika; Khosravı, Arezoo; Ardestani, Mohammad Taha Salmanifard; Mousavi-Khattat, Mohammad; Shakeran, Zahra; Khosravi, Arezoo; Zarrabi, Ali; Genetik ve Biyomühendislik / Genetic and Bio-Engineering
Nanocarriers have demonstrated promising potential in the delivery of various anticancer drugs and in improving the efficiency of the treatment. In this study, silver nanoparticles (AgNPs) were green-synthesized using the extracts of different parts of the pomegranate plant, including the peel, flower petals, and calyx. To obtain the most efficient extract used for the green synthesis of AgNPs, all three types of synthesized nanoparticles were characterized. Then, (3-Aminopropyl) triethoxysilane-functionalized mesoporous silica nanoparticles (MSNs-APTES) decorated with AgNPs were fabricated via a one-pot green-synthesis method. AgNPs were directly coated on the surface of MSNs-APTES by adding pomegranate extract enriched with a source of reducing agent leading to converting the silver ion to AgNPs. The MSN-APTES-AgNPs (MSNs-AgNPs) have been thoroughly characterized using nanoparticle characterization techniques. In addition, DNA cleavage and hemolysis activities of the synthesized nanoparticles were analyzed, confirming the biocompatibility of synthesized nanoparticles. The Doxorubicin (DOX, as a breast/cervical anti-cancer drug) loading (42.8%) and release profiles were investigated via UV-visible spectroscopy. The fibroblast, breast cancer, and cervical cancer cells' viability against DOX-loaded nanoparticles were also studied. The results of this high drug loading, uniform shape, and small functionalized nanoparticles demonstrated its great potential for breast and cervical cancer management.
Citation Count: 14
Analysis of complications following posterior vertebral column resection for the treatment of severe angular kyphosis greater than 100°
(Turkish Assoc Orthopaedics Traumatology, 2017) Atici, Yunus; Balioglu, Mehmet Bulent; Kargin, Deniz; Mert, Muhammed; Albayrak, Akif; Kaygusuz, Mehmet Akif
Objective: The aim of this study was to evaluate the complications, efficacy and safety of posterior vertebral column resection (PVCR) in severe angular kyphosis (SAK) greater than 100 degrees. Methods: The medical records of 17 patients (mean age 17.9 (range, 9-27) years) with SAK who underwent PVCR, were reviewed. Mean follow-up period was 32.2 (range, 24-64) months. Diagnosis of the patients included congenital kyphosis in 11 patients, post-tuberculosis kyphosis in 3 patients and neurofibromatosis in 3 patients. The sagittal plane parameters (local kyphosis angle, lumbar lordosis, sagittal vertical axis, pelvic tilt, sacral slope and pelvic incidence) were measured in the preoperative and the early postoperative periods and during the last follow-up on the lateral radiographs. Results: The mean preoperative localized kyphosis angle was 121.8 degrees (range, 101 degrees-149 degrees). The mean local kyphosis angle (LKA) was 71.5 degrees at postoperatively evaluation (p < 0.05). Complications were detected in 12 patients (70.6%) with spinal shock in 4 patients, hemothorax in 3 patients, postoperative infection in 2 patients, dural laceration in 2 patients, neurological deficit in 2 patients (1 paraplegia and 1 root injury), the shifted cage in 2 patients and rod fracture in 2 patients. Neurological events occurred in six patients (35%) with temporary neurological deficit in 5 patients and permanent neurological deficit in 1 patient. Conclusion: PVCR is an efficient and a successful technique for the correction of SAK. However, it can lead to a large number of major complications in SAK greater than 100 degrees. Level of evidence: Level IV, therapeutic study. (C) 2017 Turkish Association of Orthopaedics and Traumatology. Publishing services by Elsevier B.V.
Citation Count: 33
Analysis of Entanglement Measures and LOCC Maximized Quantum Fisher Information of General Two Qubit Systems
(Nature Portfolio, 2014) Erol, Volkan; Ozaydin, Fatih; Altintas, Azmi Ali
Entanglement has been studied extensively for unveiling the mysteries of non-classical correlations between quantum systems. In the bipartite case, there are well known measures for quantifying entanglement such as concurrence, relative entropy of entanglement (REE) and negativity, which cannot be increased via local operations. It was found that for sets of non-maximally entangled states of two qubits, comparing these entanglement measures may lead to different entanglement orderings of the states. On the other hand, although it is not an entanglement measure and not monotonic under local operations, due to its ability of detecting multipartite entanglement, quantum Fisher information (QFI) has recently received an intense attraction generally with entanglement in the focus. In this work, we revisit the state ordering problem of general two qubit states. Generating a thousand random quantum states and performing an optimization based on local general rotations of each qubit, we calculate the maximal QFI for each state. We analyze the maximized QFI in comparison with concurrence, REE and negativity and obtain new state orderings. We show that there are pairs of states having equal maximized QFI but different values for concurrence, REE and negativity and vice versa.
Citation Count: 9
An analysis of general surgery theses set up between years 1998-2018 in Turkey: Evidence levels and publication rates of 1996 theses
(Turkish Surgical Assoc, 2020) Ferhatoglu, Murat Ferhat; Kivilcim, Taner; Kartal, Abdulcabbar; Filiz, Ali Llker; Kebudi, Abut
Objective: Setting up and advocating a thesis is mandatory at the end of the residency training program to become a specialist in general surgery according to the regulations on medical specialization in Turkey. Writing a thesis helps the resident to learn to ask structured questions, assembling the most accurate study design, managing the study process, collecting the results and building a conclusion with medical implications. In this descriptive study, we aimed to investigate the publication rates of the theses written in the field of general surgery and to assess the properties of the published theses. Material and Methods: We performed an online search on September 1, 2018, about the theses of general surgery residents on the website of National Thesis data center of Academic Educational Board in Turkey including theses of medical residents in university-affiliated hospitals and analyzed theses accomplished between 1998-2018. The publication status of the theses was assessed by the entry of author name, the title of the theses and keywords of the theses by using the search engines of PubMed, Google Scholar and Turkish Academic Network and Information Center Turkish Database (ULAKBIM). Data were presented in a descriptive form as absolute numbers and percentages. Results: Between 1998-2018, 1996 theses were completed. 393 (20.5%) of these were published in a journal, and 288 (14.4%) were published in a journal indexed in SCI/SCIE. According to research methodologies, 79.2% of the experimental studies were published in SCI/SCIE indexed journals. Conclusion: Publication rates of the theses in the field of general surgery are low as they are in other specialties of medicine. This descriptive study might give an idea about the low scientific publication rates of general surgery theses. Further studies are needed to understand the underlying factors, which are responsible for this scant scientific performance.
Citation Count: 0
Analysis of morphological parameters in pelvic radiography and hip MRI: A practical reporting recommendation
(ARSMB-KVBMG, 2021) Cicek,E.D.; Cevik,H.
Although numerous criteria have been proposed to define abnormal hip morphology, mostly used in the diagnosis of femoroacetabular impingement, it is not a practical approach to measure all of these parameters in all cases without clinical suspicion. In this study, our aim was to develop an evaluating and reporting standardization for routine hip examinations to define both hip morphology and impingement. A total of 108 patients with routine hip magnetic resonance imaging (MRI) and antero-posterior pelvic radiograph (PR) were included in this retrospective study. Alpha angle (AA), acetabular depth (AD), acetabular protrusion, acetabular anteversion, collodiaphyseal angle (CDA), lateral center-edge angle (LCEA) and Tönnis angle (TA) were measured. The differences and associations between these parameters were evaluated according to imaging modality or plane, and sex. Although a significant difference has been found between the axial AA and the coronal AA mean values measured on MRI, there was also a strong correlation. Coronal measurements were significantly higher. AA values measured in PR and coronal MRI were comparable. Males had higher AA in both planes as compared to females. There were no significant differences between CDA values in MRI and PR. There was a significant difference and a moderate correlation between AD values in MRI and PR. We suggest that routine reports should include a measurement of AA in two planes, and measurement of CDA in PR or MRI. Due to the difference in AD between MRI and radiography, LCEA or TA may represent better alternatives. Checking for a negative Tönnis sign would represent a practical approach. © 2021, Acta Orthopædica Belgica.
Citation Count: 4
Antibiotic prescribing habits of the clinicians dealing with dental implant surgery in Turkey: a questionnaire study
(Springer Japan Kk, 2020) Çakır, Merve; Yalçın Ülker, Gül Merve; Meral, Deniz Gökçe; Ağız,Diş ve Çene Cerrahisi / Oral, Dental and Maxillofacial Surgery
Purpose Although various prophylactic and/or postoperative systemic antibiotic regimens have been suggested to minimize failure after dental implant placement and postoperative infection, the role of antibiotics in implant dentistry is still controversial. The purposes of this questionnaire study were to determine the current antibiotic prescribing habits of clinicians in conjunction with dental implant placement and to understand whether any consensus has been reached among implant surgery performing clinicians. Methods An electronic questionnaire was sent by electronic mail to all members of the Turkish Dental Society. The questions were related to whether antibiotics were routinely prescribed either pre- or/and postoperatively during routine dental implant placement. The respondents were also asked to specify their workplace and education. The results were analyzed using SPSS software. Descriptive and chi-square analyses were used to compare categorical data; Kruskal-Wallis test was used to compare the quantitative data by category. Results A total of 429 members responded to the questionnaire. The clinicians having more experience had a greater tendency to prescribe preoperative antibiotics (p< 0.001), but there was no statistically significant difference between the postoperative antibiotic prescription choice of the clinician according to the clinicians' experience (p> 0.05). A total of 175 of the clinicians preferred to prescribe preoperative antibiotics when there was systemic comorbidity; 99 of the clinicians preferred to prescribe antibiotics before every implant surgery. The aminopenicillins were the most commonly prescribed antibiotics by the clinicians. A total of 38.58% of the respondents (n= 130) who were prescribing preoperative antibiotics, 2000 mg aminopenicillin was given 1 h before the surgical procedure. Dentists and solo private practitioners were prescribing more preoperative antibiotics (p< 0,05). Conclusions There was no consensus among clinicians regarding the use of antibiotics in association with routine dental implant placement. Aminopenicillins were the most commonly prescribed antibiotics for both pre- and postoperatively. Furthermore, most of the antibiotic regimens being used are not in accordance with the current published data.
Citation Count: 0
The antidepressant-like effects of kisspeptin-10 are reversed by kisspeptin antagonist peptide 234 in male rats
(Cellular and Molecular Biology Association, 2024) Keleştimur, Haluk; Kacar, E.; Yardimci, A.; Ertugrul, N.U.; Bulmus, O.; Ercan, Z.; Kelestimur, H.; Fizyoloji / Physiology
Kisspeptins are reported to be the most potent activators of the hypothalamus-pituitary-gonadal (HPG) axis known to date. Kisspeptin potently elicits gonadotropin-releasing hormone (GnRH) release and luteinizing hormone (LH) secretion, even in the pre-pubertal period. Beyond the hypothalamus, kisspeptin is also expressed in limbic and paralimbic brain regions, which are areas of the neurobiological network primarily implicated in emotional behaviors alongside sexual functions. Therefore, an increasing body of studies has implicated kisspeptin as having many influences on emotional behaviors. The study was set out to explore if the kisspeptin/GPR54 signaling system is required for the anti-depressant-like effect of kisspeptin-10 (KP-10), besides the regulation of the HPG axis. To test this concept, peptide 234 (P234), a kisspeptin antagonist, was given to the male rats, and its modulatory effect on the anti-depressant-like effects of kisspeptin was investigated by using a forced swimming test (FST). The study has also sought to know whether kisspeptin can exert its effects through adrenergic and serotonergic receptors. To investigate this, the agents yohimbine (Yoh), an alpha-2 adrenergic receptor antagonist, and cyproheptadine (Cry), a non-selective 5-HT2 serotonergic receptor antagonist, were administered in the experiments. Our results indicate that, in rats, the anti-depressant-like effects of KP-10 in a modified rat FST are mediated by GPR54 receptors since the kisspeptin antagonist peptide 234 reversed kisspeptin-induced anti-depressant-like effects. Our data also demonstrate that the antidepressant-like effects of kisspeptin, at least in part, are mediated by an interaction of the alpha-2 adrenergic and 5-HT2 serotonergic receptors. © 2024 Cellular and Molecular Biology Association. All rights reserved.
Citation Count: 1
Applications of various stereological tools for estimation of biological tissues
(Wiley, 2023) Altunkaynak, Berrin Zühal; Kocaman, Adem; Elamin, Abdalla A.; Mohamed, Hamza; El Elhaj, Abubaker; Altunkaynak, Berrin Zuhal; Histoloji ve Embriyoloji / Histology and Embriology
To provide concise and brief important stereological application methods and techniques for estimating biological tissues. Stereology studies the quantity of biological tissue using little practice and the low price of counting and preparing tissue slices to obtain direct and accurate results. Since their establishment, the stereological techniques underwent much improvement, thus allowing more precise analysis of target structures using various approaches. Using stereological tools, advances in stereological techniques made the target tissues or organs represented by 2D instead of 3D dimensions. Process tools estimate volume, area and length. According to the exciting tissue and aims, the stereological tools perform differently. This review summarizes various stereological tools and techniques, providing brief information about the orientation method, slicer probe method, Delesse's principle, Cavalieri principle, disector, fractionator, nucleator, virtual cycloids and saucer, which are described in detail.
Citation Count: 0
An appropriate artificial intelligence technique for plastic materials recycling using bipolar dual hesitant fuzzy set
(Nature Portfolio, 2024) Ramya, Lakshmanaraj; Thilagasree, Chakkarapani Sumathi; Jayakumar, Thippan; Peter, Antony Kishore; Akhir, Emelia Akashah P.; Ferrara, Massimiliano; Ahmadian, Ali
Plastic recycling has become more important than ever as the globe struggles with growing environmental issues. This research explores the significant environmental impact of recycling plastic and its growing relevance. The pervasive material known as plastic presents a complex risk to both human health and ecosystems in contemporary life. It exacerbates problems including marine pollution, habitat damage, and wildlife entanglement because of its persistence in landfills and seas, which leads to serious ecological deterioration. In addition, producing plastic uses a lot of energy and produces a lot of greenhouse gas emissions, which exacerbate climate change. Through the use of multi-criteria decision making (MCDM), this study emphasizes how vital it is to support recycling activities in order to protect the environment and promote a sustainable future. The elimination and choice ex-pressing reality (ELECTRE) approach is used to rank the alternatives in this proposed research study that employs bipolar dual hesitant fuzzy sets (BDHFs). The most efficient and versatile outranking method for making decisions is the BDHF-ELECTRE approach. The weights of environment, economic, social, technical, and finally safety is computed using the entropy distance metric. The economic factor received the highest score of 0.2945 among the other factors since economic considerations are crucial in choosing the most efficient plastic recycling method, as they ensure sustainability, cost-effectiveness, resource allocation, and overall feasibility in managing plastic waste. The decision-makers determined that the mechanical recycling approach ought to be prioritized over all others for the efficient recycling of plastic waste. The robustness of the system is examined in the sensitive and comparative analyses. The proposed MCDM technique thus presents a viable solution, mitigating the adverse effects of plastic waste by conserving resources, reducing energy consumption, and curbing pollution.
Citation Count: 1
Assessment of IL-7RA T244I Polymorphism as a Risk Factor of Multiple Sclerosis in Turkish Population
(Turkish Neuropsychiatry Assoc-turk Noropsikiyatri dernegi, 2020) Unsal, Mirac Aysen; Manukyan, Nuket Yildiz; Isik, Nihal; Direskeneli, Guher Saruhan
Introduction: The T244I variant of the IL-7RA gene, rs6897932, is one of the first polymorphisms found to be associated with the development of multiple sclerosis (MS). Although several studies provided evidence for the association of MS and this variant, other studies could not confirm this result. These inconsistent results suggest that the role of this polymorphism in the development of disease is associated with ethnicity. Methods: We investigated rs6897932 polymorphisms in a large cohort of patients with MS and healthy controls in a turkish population. Results: In our study, there were no significant differences in genotype frequencies in the IL-7RA rs6897932 polymorphism and no significant difference between C and T alleles in patients with MS and controls. Conclusion: This study is the first to evaluate the risk of the rs6897932 polymorphism in turkish patients with MS.
Citation Count: 4
Assessment of Implant Stability of Patients With and Without Radiotherapy Using Resonance Frequency Analysis
(Allen Press inc, 2015) Karayazgan-Saracoglu, Banu; Atay, Arzu; Zulfikar, Haluk; Erpardo, Yuksel
The purpose of this study was to clinically monitor the stability of dental implants in patients with and without a history of radiotherapy, using resonance frequency analysis over 1 year. The stability of patients with 80 implants was monitored with resonance frequency analysis (Osstell Mentor) over 1 year. Data were assessed with Mann-Whitney U test and correlation analysis. Irradiated maxillary implants showed statistically lower values than the mandibular implants at a significant level (P < .05).
Citation Count: 3
Assessment of lipid profile and some risk factors of atherosclerosis in children whose parents had early onset coronary artery disease
(Sociedad Argentina de Pediatria, 2017) Bornaun,H.; Öner,N.; Nisli,K.; Öztarhan,K.; Yavuz,T.; Türkoglu,Ü.; Ömeroglu,R.E.
Background/Aim: The objective of our study was to analyze the lipid profile and some risk factors of atherosclerosis such as oxidized-low density lipoprotein (ox-LDL), small dense LDL (sd LDL) in the offspring of patients with premature coronary heart disease (CHD). Population and Methods: Children whose parents had early onset CHD were matched with age and sex pairs. Study and controls were analyzed for lipid levels, apolipoproteins (Apo- A,B,E), ox-LDL, sd LDL and lipoprotein (a) [Lp(a)]. The data were evaluated with SPSS using "Student t and Mann-Whitney U" tests. Results: The study group children (n: 43) had higher LDL, Lp(a) and ox-LDL levels, ratios of TC/HDL, Apo-B/A, LDL/HDL and ox-LDL/HDL (p<0.05) than control group. Conclusion: These findings suggest that dyslipidemia and increased LDL, Lp(a) and ox-LDL levels are common in the offspring of patients with early onset CHD and account largely for their familial predisposition for CHD.
Citation Count: 8
Association between blood pressure, inflammation and spirometry parameters in chronic obstructive pulmonary disease
(Korean Assoc internal Medicine, 2019) Arslan, Sulhattin; Yildiz, Gursel; Ozdemir, Levent; Kaysoydu, Erdal; Ozdemir, Bulent
Background/Aims: Many systems including the cardiovascular system (ischemic heart diseases, heart failure, and hypertension) may act as comorbidities that can be seen during the course of chronic obstructive pulmonary disease (COPD). Comorbidities affect the severity and prognosis of COPD negatively. Nearly 25% of patients with COPD die due to cardiovascular diseases. In this study, we aimed to evaluate the relationship between the blood pressure, inflammation, hypoxia, hypercapnia, and the severity of airway obstruction. Methods: We included 75 COPD patients in the study with 45 control cases. We evaluated age, sex, body mass index, smoking history, C-reactive protein levels, 24-hour ambulatory blood pressure Holter monitoring, arterial blood gas, and respiratory function tests of the patient and the control groups. Results: In COPD patients, the night time systolic, diastolic blood pressures and pulse per minute and the mean blood pressures readings were significantly elevated compared to the control group (p < 0.05). In the correlation analysis, night time systolic pressure was associated with all the parameters except forced expiratory volume in 1 second (FEV1%). Diastolic blood pressure was associated with pH and HCO3 levels. The mean night time, day time pulse pressures and 24-hour pulse per minute values were also associated with all the parameters except FEV1%. Conclusions: In this study we found that parameters of systolic and diastolic blood pressures and pulse pressures were significantly elevated in COPD patients compared to the control groups. Blood pressure was associated blood gas parameters and inflammation parameters in COPD patients. This, in turn, may cause understanding of the pathophysiology of COPD and its complications.

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