Browsing by Author "Babaoglu, Kadir"

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Citation Count: 2
Evaluation of Early Repolarization Pattern in Male Teenage Competitive Athletes and Association With Left Ventricular Remodeling
(Aves, 2021) Cetin, Suha; Akgun, Evic Zeynep; Babaoglu, Kadir
Objective: Early repolarization pattern (ERP) on electrocardiogram is more common among young athletes than in the general population, and has been considered a benign finding. However, ERP has been associated with increased risk of sudden cardiac death. The objectives of this study were to evaluate ERP in teenage athletes; investigate associations between ERP and echocardiographic findings of the left ventricle (LV); and to describe the impact of different sports disciplines on ERP. Methods: ERP was assessed in male teenage athletes from sports institutions for 5 different types of sport--basketball, swimming, football, wrestling, and tennis. All had been training for at least 3 hours per week for over at least 2 years. ERP was defined as J-point elevation >= 1 mV in 2 contiguous and/or lateral leads. A conventional echocardiography was performed in all athletes. Results: ERP was evaluated in 159 athletes with a mean age of 14 (range 10-18 years). It was more common in those training with combined exercise. There was no association between ERP and echocardiographic findings of left ventricular remodeling and geometric pattern. Conclusion: ERP is a frequent finding among teenage athletes. However, frequency varies by sports type, being more common in those training with combined exercise. It is not associated with structural echocardiographic alterations and is primarily seen as an electrophysiological change.
Citation Count: 33
Subclinical anthracycline-induced cardiotoxicity in long-term follow-up of asymptomatic childhood cancer survivors: Assessment by speckle tracking echocardiography
(Wiley, 2018) Cetin, Sueha; Babaoglu, Kadir; Basar, Evic Z.; Deveci, Murat; Corapcioglu, Funda
ObjectiveSurvivors of childhood cancer treated with anthracyclines carry the risk for developing late-onset cardiotoxicity. The purpose of this study was to evaluate left ventricular (LV) function in this patient group and compare it with healthy controls by means of conventional and speckle tracking echocardiography (STE) after exposure to chemotherapy. Material and methodsConventional and STE were performed in 45 childhood cancer survivors (mean age 114.6; 26 male) treated with anthracyclines (median cumulative dosage 240mg/m(2); range, 100-460) and compared with age, gender and body surface area matched healthy controls. Follow-up period after chemotherapy was 21.917.8months. Blood samples were taken from survivors and controls to determine brain natriuretic peptide (BNP). ResultsFollowing anthracycline exposure, pediatric cancer survivors had lower longitudinal, radial anteroseptal, and radial anterior strain values compared to controls (P<.05). The calculated global longitudinal and global radial strain values were lower compared to the control group (P<.05). Both groups had normal ejection fraction (EF) and fractional shortening (FS). Brain natriuretic peptide (BNP) levels of both groups were in the normal range. ConclusionDespite normal EF and FS, children exposed to anthracycline therapy may have late-onset subtle changes of LV strain values measured by STE. Whether these changes of strain can predict future risk of developing heart failure needs to be explored in further studies.