Browsing by Author "Bal,I."

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Citation Count: 0
Conducting Polymers for Ophthalmic Applications
(CRC Press, 2022) Bal,I.; Kucuk,I.
Drug delivery into the eye is always difficult when considering the other organs and tissues. An eye is a well-protected organ by defense mechanisms including various complex structures. These barriers, which protect the eye against foreign molecules or pathogens, also prevent drug-active substances through the eye. The vast majority of conventional treatment methods are suffering from low bioavailability (i.e., rapid clearance or low penetration into tissues). Recent developments in biomedical fields ensure promising alternatives to overcome these problems. Biodegradable polymers in ocular(ophthalmic) formulations exhibit improved residence time and mucoadhesion properties. Nanotechnology advancements have the potential to revolutionize the biomedical industry. Nano-scaled drug delivery systems help to increase bioavailability by allowing the effective dose to reach deeper tissues. Additionally, the development of metal-organic framework (MOF)-based materials is exciting and has all the properties it needs to be used in biomedical applications. It has been modified to be used in drug delivery systems, including ocular systems, thanks to its adjustable pore size and high drug loading capacity. This chapter describes using of polymers and MOF-based structures in ocular applications. © 2022 selection and editorial matter, Ram K. Gupta.
Citation Count: 6
The effect of solution temperature on chemically manufactured cds samples
(S.C. Virtual Company of Phisics S.R.L, 2021) Bal,I.; Baykul,M.C.; Saraç,U.
In this paper, CdS samples were chemically coated onto glasses from an aqueous cadmium acetate solution. The resultant samples were analyzed depending on the solution temperature (ST) varied between 65 and 85 °C. Structural analysis confirmed that the ST plays a significant role on the crystallinity. A better crystallization was achieved at the ST of 80 °C. The direct optical band gaps were found to be in the range of 2.18 to 2.42 eV. The ST exhibited a remarkable influence on the surface morphology. Increasing ST from 65 to 80 °C significantly reduced the surface roughness and particle size. The sample chemically produced at the ST of 85 °C exhibited the highest surface roughness and the largest particle size. There was a good relationship between the energy band gap and the surface morphology. Further morphological analysis showed that the ST does not play a role on the surface texture. The highest crystallinity, the lowest surface roughness, the smallest particle size, the lowest band tail energy and the highest optical band gap (2.42 eV) were obtained for the sample manufactured at the ST of 80 °C, indicating that the optimum ST was 80 °C under the applied experimental conditions. © 2021, S.C. Virtual Company of Phisics S.R.L. All rights reserved.