Browsing by Author "Ceken,K."

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    Discovering similarities for the treatments of liver specific parasites
    (2011) Yildirim,P.; Ceken,K.; Saka,O.
    Medline articles are rich resources for discovering hidden knowledge for the treatments of liver specific parasites. Knowledge acquisition from these articles requires complex processes depending on biomedical text mining techniques. In this study, name entity recognition and hierarchical clustering techniques were used for advanced drug analyses. Drugs were extracted from the articles belonging to specific time periods and hierarchical clustering was applied on parasite and drug datasets. Hierarchical clustering results revealed that some parasites have similar in terms of treatment and the others are different. Our results also showed that, there have not been major changes in the treatment of liver specific parasites for the past four decades and there are problems associated with the development of new drugs. Both pharmaceutical initiatives and healthcare providers should investigate major drawbacks and develop some strategies to overcome these problems. © 2011 Polish Info Processing Soc.
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    Discovery of the Similarities for Parasites
    (Institute of Electrical and Electronics Engineers Inc., 2020) Yildirim,P.; Ceken,K.
    In this paper we report on a study for discovering hidden patterns in commonly seen parasites by using abstracts from MEDLINE database. Parasites affect millions of people in the world and cause tremendous morbidity and mortality. Diagnosing parasites can be difficult because some symptoms and related to gene-proteins can be common to some of them. We utilize a web based biomedical text mining tool to find symptoms and gene-proteins. After selecting the most common symptoms and gene-proteins, we create two datasets with the frequencies of symptoms and gene-proteins for each parasite. For this work we selected the k-means algorithm for clustering analysis and apply it on the datasets. In addition, we compared different algorithms to observe the performance of k-means. Clustering analysis generated different types of groups of parasites. Although the results are not 100% certain, they can make positive contributions to medical researchers and experts for the diagnosis of parasites. © 2020 IEEE.