Browsing by Author "Kaya, Ayşe Demet"

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Citation Count: 0
Association between Pityriasis Rosea (PR) and HHV-6/HHV-7 Infection: Importance of Sample Selection and Diagnostic Techniques
(Mdpi, 2024) Kurc, Mine Aydin; Erfan, Gamze; Kaya, Ayse Demet; Gulen, Dumrul; Oznur, Meltem; Yanik, Mehmet Emin; Tıbbi Mikrobiyoloji / Medical Microbiology; Tıbbi Mikrobiyoloji / Medical Microbiology
Recent studies have focused on the role of human herpesvirus 6 (HHV-6) and human herpesvirus 7 (HHV-7) in PR etiology with varying results. In our study, with the approach that the discrepancy between the results may be related to the different samples and techniques used, we aimed to clarify the etiology by examining tissue and plasma samples using molecular methods and evaluating the results together with serological parameters. Skin biopsies and plasma samples of twenty-five PR patients were tested to detect HHV-6 and HHV-7 DNA using calibrated quantitative real-time polymerase chain reaction (CQ RT-PCR). IgG and IgM antibodies against HHV-6 and HHV-7 were tested by enzyme-linked immunosorbent assay and indirect immunofluorescence. Of the patient group, 64% were positive for HHV-6 IgG without IgM positivity. HHV-6 DNA was present in seven tissue and ten plasma samples. HHV-7 positivity was 100% and 12% for IgG and IgM antibodies, respectively. HHV-7 DNA was detected in four tissue samples and one plasma sample. Patients with HHV-7 DNA-positive plasma and tissue samples had also HHV-7 IgM antibodies. In conclusion, our results seem to support the role of HHV-6/HHV-7 in the etiology of PR. To clarify the etiology of PR and avoid confusion, the collection of different biological materials simultaneously and the usage of CQ RT-PCR as a diagnostic technique are recommended.
Citation Count: 1
Clinical Performance of Samfilcon A Contact Lenses in Intensive Digital Device Users: A Multicenter, Prospective Clinical Study
(Springer int Publ Ag, 2021) Ucakhan, Omur O.; Tasindi, Emrullah; Toker, Ebru; Ciftci, Ferda; Kurna, Sevda Aydin; Acar, Mutlu; Barakat, Maxime; Tıbbi Mikrobiyoloji / Medical Microbiology
Introduction To evaluate patient satisfaction with samfilcon A contact lenses (CLs) in intensive digital device users with myopia and to compare patient satisfaction with samfilcon A lenses to prior experience with senofilcon A or lotrafilcon B CLs. Methods This was a comparative, prospective, national study conducted at 14 centers in Turkey. Subjects were adults aged 18 and 45 years with myopia (range -0.25 D to -6.00 D) who spend a minimum of 3 hours viewing digital devices (e.g., computer, smartphone). A subgroup of patients were habitual lens wearers (senofilcon A or lotrafilcon B lens wear for at least 6 months prior to enrollment). The primary assessment was patient satisfaction with samfilcon A lenses (0-100 Likert scale). Secondary assessments included patient satisfaction with samfilcon A lenses compared to patients' habitual lenses, investigator satisfaction with samfilcon A lenses and investigator-evaluated slit lamp examination findings. Results Samfilcon A lenses were given high overall ratings from both patients and investigators, with a low incidence of ocular symptoms. Overall, patients were highly satisfied with samfilcon A lenses for comfort, vision and overall performance, and stated that they would consider wearing these lenses in the future. Among habitual senofilcon A or lotrafilcon B lens wearers, samfilcon A lenses were rated significantly better than the habitual lenses in regard to comfort, vision and overall performance. Investigator assessments were also highly favorable, both at initial fit and after 4 weeks of follow-up, with no significant findings noted on slit lamp examination. Conclusion Samfilcon A lenses were rated highly by investigators in regard to fit, handling and slit lamp findings, and by novice and habitual lens wearers in regard to comfort, vision and overall performance. These results support the use of samfilcon A lenses among digital device users who seek day-long comfort and good visual acuity.
Citation Count: 0
Clinical Performance of Samfilcon A Contact Lenses in Intensive Digital Device Users: A Multicenter, Prospective Clinical Study (Aug, 10.1007/s40123-021-00389-4, 2021)
(Springer int Publ Ag, 2021) Ucakhan, Omur O.; Tasindi, Emrullah; Toker, Ebru; ciftci, Ferda; Kurna, Sevda Aydin; Acar, Mutlu; Barakat, Maxime; Tıbbi Mikrobiyoloji / Medical Microbiology
[No Abstract Available]
Citation Count: 0
Clustering of Phentermine HCL Drug from Online Patient Medication Reviews
(Elsevier, 2019) Yildirim, Pinar; Kaya, Alkan; Bilgisayar Mühendisliği / Computer Engineering; Tıbbi Mikrobiyoloji / Medical Microbiology
In this paper, a study to reveal hidden knowledge in the online patient medication reviews for phentermine HCL is presented. Phentermine HCL is used most frequently in the treatment of obesity. Obesity is a complex health disorder that affects huge amount of people. In recent years, the number of overweight people in industrialized countries has increased significantly and people who are obese are at a much higher risk for serious medical conditions such as high blood pressure, heart attack, stroke and diabetes. Considering the importance of the medication of obesity, knowledge discovery from online patient reviews is performed. Some information technologies and data mining techniques are used to discover some hidden knowledge between patient information and side effects in these reviews. Our results can give new ideas to medical researchers and pharmaceutical industry for drug safety. (C) 2019 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) Peer-review under responsibility of the Conference Program Chairs.
Citation Count: 0
Distribution and antifungal susceptibility profiles of candida species isolated from dermatomycosis patients
(2024) Kurç, Mine Aydın; Kaya, Ayşe Demet; Erfan, Gamze; Albayrak, Şule; Tıbbi Mikrobiyoloji / Medical Microbiology
Aims: Superficial mycoses are the most common dermatological diseases worldwide, and the causes are becoming increasingly resistant to antifungal agents used in treatment. The aim of our study was to identify the yeast species causing superficial mycoses and determine their susceptibilities to some antifungal agents. Methods: Skin and nail scraping samples obtained from 726 patients with suspected superficial fungal infection were collected and examined by direct microscopy and culture. Isolates were identified by conventional methods and API ID32 C (Biomeriux, France) commercial kits. The minimum inhibitory concentrations (MIC) of isolates against itraconazole, miconazole, nystatin, and terbinafine antifungals were determined by microdilution method. Results: A total of 59 yeasts were isolated from the samples. The most frequently isolated species were Candida glabrata (n=31, 52.54%), Candida guillermondii (n=9, 15.25%), and Candida albicans (n=7, 11.86%). In terms of infection sites, the most common involvement was observed in the foot (n=39, 66.1%) and nails (n=16, 27.1%). In terms of their antifungal susceptibilities, the highest resistance was detected against terbinafine (35.6%) and itraconazole (33.9%). Multidrug resistance was observed among strains of the Candida species (n=17, 28.8%). Conclusion: The most striking results of this study can be summarized as high rates of Candida glabrata isolation, increase in resistance rates, and a prevalence of 28.8% multidrug resistance. This data once again emphasize the importance of isolation, identification, and antifungal susceptibility testing in the diagnosis and effective treatment of superficial mycoses.
Citation Count: 2
Do we really need to coat the novel silicone intranasal splints with antibiotics?
(W B Saunders Co-elsevier inc, 2016) Ciftci, Zafer; Kurc, Mine Aydin; Kaya, Ayse Demet; Saracoglu, Gamze Varol; Deniz, Mahmut; Gultekin, Erdogan; Tıbbi Mikrobiyoloji / Medical Microbiology; Tıbbi Mikrobiyoloji / Medical Microbiology
Purpose: The novel silicone intranasal splints are suggested to resist biofilm formation due to their surface characteristics. We aimed to ascertain the necessity of coating these splints with antibiotics to prevent splint associated infections, in vitro. Materials and methods: Pieces of Doyle II airway nasal splints made of medical grade silicone were divided into two test groups, treated with either (i) 0.2% nitrofurazone solution or (ii) 0.2% nitrofurazone containing ointment, and a control group, treated with (iii) 0.9% saline. Splint pieces were then incubated with Staphylococcus aureus solutions at 37 degrees C for 48 and 96 h. Following this, the splint pieces were incubated in 20 ml Mueller Hinton agar and appearing colonies were counted. Results: Following 48 and 96 h of incubation, the colonization rates in the saline group were significantly higher than the nitrofurazone ointment group (p < 0.001). The colonization rates in the liquid nitrofurazone group were significantly lower in comparison to the nitrofurazone ointment group (p < 0.001 and p = 0.019 respectively). Conclusions: The method of coating the splints with antibiotic was superior to using uncoated splints in terms of preventing S. aureus colonization. The rather smooth surfaces of the splints were insufficient to block bacterial colonization and coating them with antibiotics seems to be beneficial for the prevention of infections. (C) 2016 Elsevier Inc. All rights reserved.
Citation Count: 4
Does the right or left hemisphere involvement affect swallowing in patients with hemiplegia?
(IOS Press BV, 2020) Sayaca,C.; Sapcióglu,T.Y.; Kaya,D.; Tıbbi Mikrobiyoloji / Medical Microbiology
BACKGROUND: Stroke is one of the most important causes of swallowing difficulty. It is seen in one of every two patients with stroke. Although the swallowing function is controlled by both hemispheres, it is unknown which hemisphere is more dominant than another for controlling the swallowing function. However, the aspiration and pharyngeal phase dysfunction can be seen in right hemisphere involvement while oral phase dysfunction can be seen in left hemisphere involvement. OBJECTIVE: The aim of this study was to investigate whether water swallowing performance, deep cervical flexor muscle endurance, and maximum phonation time were affected in right handed patients with hemiplegia. STUDY DESIGN: The study was designed as a cross-sectional study. METHODS: Patients with unilateral strokes that damaged the right (Group I: n = 37) and left (Group II: n = 20) hemispheres were included. Swallowing difficulties were evaluated with the Turkish version of the Eating Assessment Tool. The water swallowing performance was measured with the 100 ml water swallow test. The muscle endurance (ME) of deep neck flexors was measured in the chin-tuck position. The laryngeal function was measured indirectly with maximum phonation time (MPT). RESULTS: The mean age of patients was 73.54±7.28 years in Group I and the mean age of patients was 73.15±6.94 years in Group II. There were no differences in maximum phonation time, water swallowing performance (swallow volume, capacity, and speed), and swallowing difficulty (p > 0.05). The neck flexor muscular endurance of patients with unilateral strokes that damaged the left hemisphere was better than the patients with unilateral strokes that damaged the right hemisphere (p < 0.05). There was a relationship between MPT and ME, MPT and swallowing difficulty, ME and swallowing difficulty (r:0.637, p:0.000; r:-0.465, p:0.004; r:-0.473, p:0.003 respectively) in the right hemisphere involvement patients. There was a relationship between swallowing difficulty to swallowing volume and swallowing capacity (respectively, r:-0.402 and p:0.014; r:-0.473 and p:0.003) in the patients with unilateral strokes that damaged the right hemisphere. There was no relationship between other parameters in Group I (p > 0.05). There was no relationship between all parameters in Group II (p > 0.05). CONCLUSIONS: This study is the first study to investigate whether water swallowing performance, deep cervical flexor muscle endurance, and maximum phonation time were affected in right handed patients with unilateral strokes that damaged the right or left hemispheres. In light of the findings of the study, it was thought that swallowing should be evaluated in detail especially in hemiplegic patients with right hemisphere involvement. There is a need for studies examining the results of swallowing rehabilitation on right or left hemisphere in hemiplegic individuals. © 2020 - IOS Press and the authors. All rights reserved.
Citation Count: 29
Effects on Lower Extremity Neuromuscular Control Exercises on Knee Proprioception, Muscle Strength, and Functional Level in Patients with ACL Reconstruction
(Hindawi Ltd, 2019) Kaya, Defne; Guney-Deniz, Hande; Sayaca, Cetin; Calik, Mahmut; Doral, Mahmut Nedim; Tıbbi Mikrobiyoloji / Medical Microbiology
Objective. The purpose of this study was to determine the effects of lower extremity motor control exercises on knee proprioception, muscle strength, and functional level in patients with anterior cruciate ligament reconstruction (ACL-R). Materials and Methods. Thirty-two of the 57 patients with ACL-R using tibialis anterior allografts were divided into two groups. Group I: lower extremity motor control exercises were added to the standard rehabilitation program. Group II: standard rehabilitation program was applied. Effects of lower extremity motor control exercises on quadriceps and hamstring muscles strength, knee joint position sense, and hop test were evaluated. Results. There were no differences in muscle strength and endurance of the quadriceps and hamstring between the operative and nonoperative sides in Group I (p>0.05) while there were significant differences in strength of the quadriceps and hamstring between the operative and nonoperative sides in Group II (p<0.05). There were significant differences in the endurance of the quadriceps and hamstring and knee joint position sense at 15 degrees, 45 degrees, and 75 degrees between the operative sides of the patients in both groups (p<0.05). Conclusions. The neuromuscular control exercises program was found to be more effective in reducing the difference in strength while the standard program was found to be more effective in reducing the difference in endurance between the operated knee and the other knee. This study revealed that neuromuscular control exercises should also be used to improve knee proprioception sense following ACL-R.
Citation Count: 0
Emergence of Drug-Resistant Pathogens in a Neonatal Intensive Care Unit
(Georg Thieme verlag Kg, 2023) Aydinli, Aydin; Sertel Selale, Deniz; Kaya, Ayse Demet; Tıbbi Mikrobiyoloji / Medical Microbiology
Objective Neonatal bloodstream infections (BSIs) due to drug-resistant pathogens are a major cause of neonatal morbidity and mortality. Unfortunately, data regarding the pathogens and their resistance profile are limited in developing countries. The aim of this study was to determine the bacteriological profile and antimicrobial susceptibility patterns in neonatal BSI at a university hospital in Turkiye.Methods Medical records of neonates with suspected sepsis were retrospectively reviewed during the study period (between January 1, 2018, and December 31, 2020) for demographic data, blood culture, and antimicrobial susceptibility test results.Results During the study period, 117 BSI episodes were encountered in 106 neonates. The most common pathogen isolated was Staphylococcus epidermidis ( n = 86, 73.5%), followed by Klebsiella pneumoniae ( n = 11, 9.4%). Methicillin resistance among staphylococci (77/93, 82.8%) and extended-spectrum beta-lactamase (ESBL) production among Enterobacterales (14/17, 82.4%) were common. Gentamicin resistance was detected in 70.1% (54/77) of methicillin-resistant staphylococci and 78.6% (11/14) of ESBL (+) Enterobacterales. Vancomycin and colistin resistance were not detected.Conclusion The high rate of resistant pathogens encountered in neonatal BSIs underline the importance of constant surveillance of the local pathogens and their antimicrobial susceptibility patterns, which is crucial for implementing appropriate therapy that could save lives and lower the burden of antimicrobial resistance.
Citation Count: 0
Evaluation of The Effect of Different Polyetheretherketone Materials on Biofilm Formation: An in vitro Study
(Galenos Publ House, 2024) Kayaalti-Yuksek, Sibel; Atalik, Kevser; Karademir, Beguem; Saridag, Serkan; Kaya, Ayse Demet; Degirmenci, Kuebra; Tıbbi Mikrobiyoloji / Medical Microbiology; Protetik Diş Tedavisi / Prosthetic Dental Treatment; Periodontoloji / Periodontology
Objective: The aim of this in vitro study was to investigate microorganism adhesion and biofilm formation between pure and ceramic-reinforced polyetheretherketone (PEEK) materials. Methods: A total of 72 rectangular (8 x 8 x 4 mm) samples were prepared from pure-PEEK without filler and PEEK (Ceramicreinforced PEEK - bio high-performance polymer) containing 20% nano-ceramic filler. A profilometer contact surface measurement device was used to assess the surface roughness of the samples. PEEK groups (36 pure PEEK, 36 Ceramic-reinforced PEEK) were divided into 4 sub-groups of 9 according to the microorganism strains. Staphylococcus aureus [American Type Culture Collection (ATCC 29213)], Acinetobacter baumannii (ATCC 19606), Enterococcus faecalis (ATCC 29212), and Candida albicans (ATCC 10231) standard strains were used for microbiological analysis. Blocks were added to 24-well microplates containing suspensions of microorganisms and were incubated at 37 degrees C for 72 hours. Microplates were read at a wavelength of 490 nm using crystal violet. Results: No significant difference was determined between the PEEK groups in terms of surface roughness. No significant differences in biofilm formation of S. aureus , A. baummanii , E. faecalis , and C. albicans strains were found between the PEEK groups (p>0.05). In the pure -PEEK, the highest adhesion was recorded in S. aureus (p<0.001), and the lowest adhesion in C. albicans (p<0.001). In the ceramic -reinforced PEEK group, S. aureus and A. baummanii adhesions were observed more than E. faecalis and C. Albicans (p<0.001). Conclusion: The results of this investigation demonstrated no significant differences in the biofilm formation of different strains between PEEK materials. This was a preliminary study to define the biological characteristics of ceramic -reinforced PEEK. There is a need for further comparative and clinical studies on this subject.
Citation Count: 0
GÜVENLİ KAN İÇİN KİME GÜVENELİM? TEKİRDAĞ İLİNDE KIZILAY KAN BAĞIŞ MERKEZİ ÇALIŞMALARININ MİKROBİYOLOJİK AÇIDAN DEĞERLENDİRİLMESİ
(2017) Saraçoğlu, Gamze Varol; Kurç, Mine Aydın; Kaya, A. Demet; Saraçoğlu, Atilla; Tıbbi Mikrobiyoloji / Medical Microbiology
Amaç: Bu araştırmanın amacı, Tekirdağ İlinde Kızılay Kan Bağışı Merkezi'ne (KKBM) yapılan gönüllü kan bağışı başvurularını ve mikrobiyolojik test sonuçlarını değerlendirmektir.Gereç ve Yöntem: Kesitsel tipte olan araştırma KKBM' nin 2010 yılı kayıtlarının incelenmesini kapsamaktadır. Veriler rutin kayıt sistemindeki bilgilerden düzenlenerek elde edildi. Çalışmanın evrenini 2010 yılında KKBM'ne gönüllü kan bağışçısı olmak için başvuran 8451 kişi oluşturdu. Çalışmada tanımlayıcı istatistik yöntemleri kullanıldı. Karşılaştırmalı analizlerde Tek yönlü varyans analizi, Student t ve Chi-square testi uygulandı. Sonuçlar, %95 güven aralığında ve iki yönlü olarak değerlendirildi. Bulgular: 2010'da KKBM'ne 8451 gönüllü kan bağışı başvurusu yapıldı. Gönüllü kan bağışçısı olarak başvuran 8451 kişinin %82.3'ünün başvurusu kabul edildi (n=6952). Kabul edilmeyen kanların %17.6'sı (n=1489) geçici, %0.1'i (n=10) kesin ret tanısı aldı; alınan kanların % 0.3'ü (n=23) reaktif sonuç nedeniyle imha edildi. Kanların %1.11'inde (n=77) mikrobiyolojik tarama testleri pozitif bulundu. HBsAg pozitifliği %0.98, Anti-HCV pozitifliği %0.10 ve VDRL serolojik pozitifliği %0.03 bulundu. Anti-HIV pozitif kan saptanmadı. Sonuç: Çalışmamızda VDRL/RPR pozitifliği ülkemiz verileriyle benzer bulunurken, HBsAg ve Anti-HCV pozitifliğinin Türkiye geneline göre daha düşük olduğu belirlendi.
Citation Count: 1
Hemşirelik Öğrencilerinde Nazal Staphylococcus aureus Taşıyıcılığının Araştırılması
(2022) Kevser ATALIK; Aydın AYDINLI; Birsen YÜRÜGEN; Ülken Tunga BABAOĞLU; Deniz SERTEL ŞELALE; Harika DİNÇ; Ayşe Demet KAYA; Tıbbi Mikrobiyoloji / Medical Microbiology; Hemşirelik / Nursing
Amaç: Staphylococcus aureus ve Metisiline dirençli Staphylococcus aureus (MRSA) ile kolonize sağlık personeli ve sağlık alanında eğitim alan öğrenciler, hastane enfeksiyonları gelişimi açısından risk oluşturmaktadır.Nazal taşıyıcılığın belirlenmesi ve önlenmesi, enfeksiyon kontrolünde önem taşımaktadır. Bu çalışmada, hemşirelik öğrencilerinin klinik stajlara başlamadan ve staj döneminde aktif olarak sağlık kurumlarında çalışırken nazal S. aureus taşıyıcılık durumları araştırılmıştır. Gereç ve Yöntemler: Çalışmaya, 69’u birinci sınıfta, 60’ı ise üçüncü sınıfta eğitim görmekte olan toplam 129 hemşirelik öğrencisi dahil edilmiştir. Öğrencilerden alınan nazal sürüntü örnekleri koyun kanlı agar ve mannitol tuz agara ekilmiş ve bir gece inkübasyonu takiben, konvansiyonel yöntemler ile identifiye edilmiştir. Metisilin duyarlılığı disk difüzyon yöntemi ile belirlenmiştir. İstatistiki analizde Pearson Ki-Kare testi kullanılmış ve istatistiksel anlamlılık p
Citation Count: 3
Crossroads (1970) and the origin of Islamic Cinema in Turkey
(Routledge Journals, Taylor & Francis Ltd, 2015) Kaya, Dilek; Azak, Umut; Uluslararası İlişkiler / International Relations; Uluslararası İlişkiler / International Relations; Tıbbi Mikrobiyoloji / Medical Microbiology
This article focuses on Birlesen Yollar/Crossroads (Yucel cakmakli, 1970), which pioneered the Islamic National Cinema Movement in Turkey. The film discursively constructed Turkish secularist modernization as cosmetic Westernization and promoted the Islamic way of life as the only means to true happiness-a popular theme of Islamic cinema in the late 1980s and 1990s. Although the film-makers discursively posited it as an 'alternative' film, they followed the narrative conventions of melodrama, the most popular genre of the time. Moreover, they worked with famous mainstream stars. In other words, the film-makers chose to communicate the then marginal message of Islamism by reconfiguring and Islamicizing the mainstream rather than rejecting it all together. In this respect, Crossroads was an early example of the Islamist project to Islamicize modernity in Turkey that would gain momentum in the 1990s. The article attempts to reconstruct the film's historical and continuing significance by locating it within a broader discursive context and by exploring its historical development from its production through to its passage through censorship and public reception. The article also discusses the continuities between the film's discourse and current debates on secularism and Islamism in Turkey.
Citation Count: 2
Inflammation Markers in Infants of Mothers with Gestational Diabetes
(Taylor & Francis inc, 2022) Dincer, Emre; Topcuoglu, Sevilay; Arman, Didem; Kaya, Aysem; Yavuz, Taner; Karatekin, Guner; Tıbbi Mikrobiyoloji / Medical Microbiology
Aim Pentraxin-3, high sensitive CRP (HsCRP) and adropin were investigated in cord blood of infants of mothers with gestational diabetes mellitus (IDM) to evaluate the exposure of fetus to inflammation and whether there is any correlation with clinical findings. Methods Forty IDM and forty three infants whose mother did not have diabetes were included in this prospective study. Adropin, pentraxin-3 and HsCRP levels were measured in the cord blood samples. Echocardiographic measurements were performed in the first three days of life. Results Adropin and pentraxine-3 levels were significantly lower and HsCRP levels were significantly higher in IDM group. Echocardiographic measurements of myocardial hypertrophy were negatively correlated with adropin. Conclusion Alterations in these markers in IDM supports the hypothesis of in utero fetal exposure to inflammation caused by gestational diabetes mellitus. Potentially, cord blood adropin might be used as a predictor for complications of diabetes.
Citation Count: 4
Investigating the usage possibility of metal mono carboxylates(metal naphthenates) as antibacterial agent in textile applications
(inst Natl Cercetare-dezvoltare Textile Pielarie-bucuresti, 2014) Yildiz, Aylin; Oztas, Merve; Dumrul, Gulen; Yesilyurt, Murat; Atav, Riza; Agirgan, A. Ozgur; Kaya, A. Demet; Tıbbi Mikrobiyoloji / Medical Microbiology
In this study, it was aimed to produce a substance, which could be used as an antibacterial agent in textiles, from petroleum sub-products in order to extend the use of petroleum and petroleum sub-products in textiles. For this aim, complex compounds with copper, cobalt, nickel, zinc, and sodium, were produced. Then, those compounds were applied onto cotton fabric by padding process, and their antibacterial activities were evaluated according to the AATCC 147 agar diffusion test method. As a result of the trials, it was determined that best results were obtained against both gram-positive and gram-negative bacteria with copper mono carboxylate. Its activity was still present against Staphylococcus aureus and Escherichia coli after 3 washings and against Bacillus subtilis and Klebsiella pneumoniae after 10 washings.
Citation Count: 0
Investigation of therapeutic effect of Saccharomyces boulardii and translocation in immunosuppressed rats infected with Shigella sonnei
(2020) Ayşe Demet KAYA; Mustafa BEHÇET; Tıbbi Mikrobiyoloji / Medical Microbiology
Aim: To investigate the therapeutic effects of Saccharomyces boulardii (S. boulardii) and detectblood and tissue penetrations of S. boulardii and Shigella sonnei (S. sonnei) in immunosuppressedrats infected with S. sonnei.Methods: Forty rats were divided into four groups: Group A (immunosuppressed, not-treated); GroupB (immunosuppressed, treated with S. boulardii); Group C (immunosuppressed, infected with S.sonnei, treated with S. boulardii); Group D (immunosuppressed, infected with S. sonnei). After takingsamples for blood cultures, the rats were sacrificed. The large bowel, liver, spleen and mesentericlymph nodes (MLN) were removed for microbiological examination.Results: S. boulardii in group B and S. sonnei in group D were isolated from blood in some rats.Statistical analysis of our data, showed that the numbers of translocated colonies in the liver andspleen were relatively higher for S. boulardii in Group B and for S. sonnei in Group D, withoutreaching levels of statistical significance. For MLN, colony counts in Group B was higher than GroupC and A showing statistical significance.Conclusion: The administration of S. boulardii showed promising results for the therapy of S. sonneiinfection in immunosuppressed rats, but therapeutic usage of S. boulardii should be carefully assessedby taking into consideration the risk it poses versus potential benefits in risk groups.
Citation Count: 11
Is the proprioceptive neuromuscular facilitation technique superior to Shaker exercises in swallowing rehabilitation?
(Springer, 2020) Sayaca, Cetin; Serel-Arslan, Selen; Sayaca, Nurhan; Demir, Numan; Somay, Goksel; Kaya, Defne; Karaduman, Ayse; Tıbbi Mikrobiyoloji / Medical Microbiology
Purpose This prospective study was planned to investigate whether the combined isotonic technique of proprioceptive neuromuscular facilitation (PNF) is superior to Shaker exercises in improving the function of swallowing muscles. Methods Fifty individuals (30 females and 20 males; mean age 68 +/- 3.89 years) with swallowing difficulties were separated into two groups randomly. The treatment groups were Shaker and PNF groups, which performed these exercises three times in a week for6 weeks. Swallowing difficulties were determined with the Turkish version of the eating assessment tool (T-EAT-10). The 100 ml-water swallow test was used to measure capacity, volume, and speed of swallowing. Contraction amplitude changes used as a universal measurement of motor unit activity during the muscle action were measured with superficial electromyography. Result After 6 weeks of exercise training, T-EAT-10 scores decreased in both groups (p < 0.001). Water swallowing capacity and volume improved in both groups (p < 0.001). There was no change in swallowing speed in both groups (p > 0.05). Maximal voluntary contraction values of suprahyoid muscles were higher in PNF than the Shaker group (p < 0.05). Conclusion Both the types of exercise can be used in the rehabilitation of swallowing difficulties. However, the PNF technique increased the contraction amplitude values that occur during maximum contraction more than the Shaker exercises. Different functional evaluations are needed to determine the effectiveness of PNF on swallowing difficulty.
Citation Count: 2
Kinesiology of the hip
(Elsevier, 2020) Eyüboğlu,F.; Sayaca,Ç.; Çalik,M.; Korkem,D.; Tascilar,L.N.; Kaya,D.; Tıbbi Mikrobiyoloji / Medical Microbiology
This chapter introduces kinesiology of hip. It starts by anatomy (bones, static and dynamic stabilizers, veins and nerves) of hip. The chapter continues with biomechanics and osteokinematics of the hip. The relation between femur and pelvis is explained as kinesiology. Movements of the hip during walking and running are explained. At the end of the chapter, changes in the hips in neurological and orthopedic illness situations will be explained. © 2020 Elsevier Inc. All rights reserved.
Citation Count: 0
Kinesiology of the pelvis
(Elsevier, 2020) Sayaca,Ç.; Eyüboğlu,F.; Tascilar,L.N.; Çalık,M.; Kaya,D.; Tıbbi Mikrobiyoloji / Medical Microbiology
This chapter introduces the pelvis and its relationship with the lumbosacral joints. It starts by explaining the importance of pelvis, explains the anatomy and biomechanics followed by pelvic pathomechanics in selected orthopedic conditions. Sacroiliac and lumbosacral joints are also discussed as they are structurally and functionally related to pelvis. © 2020 Elsevier Inc. All rights reserved.
Citation Count: 0
Relationship between kinesiophobia and functional level in patients with gonarthrosis
(Taylor & Francis Ltd, 2018) Tascilar, L. N.; Kaya, D.; Kuyucu, E.; Erdil, M. E.; Tıbbi Mikrobiyoloji / Medical Microbiology
[No Abstract Available]