Browsing by Author "Ozdemir, Deniz Ladin"

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Citation Count: 4
Comparison of fetal and adult tympanic membrane sizes: a cadaveric study
(Springer France, 2021) Beger, Orhan; Vayisoglu, Yusuf; Ors, Alev Bobus; Ozdemir, Deniz Ladin; Muduroglu, Fatma; Taghipour, Pourya; Talas, Derya Umit
Objective The work aimed to compare fetal and adult tympanic membrane (TM) sizes for understanding dimensional development from intrauterine life to adulthood. Methods Fifty-six temporal bones (18 fetuses, 10 elderly adults, half male and half female in each group) were included in this study. Using a digital image software, the TM height, width and area were measured. Results The mean area, height and width of the TM in adults were found as 58.84 +/- 22.01 mm(2), 9.06 +/- 1.33 mm, and 8.10 +/- 1.43 mm, respectively. Moreover, the mean area, height and width of the TM in fetuses were measured as 47.62 +/- 12.57 mm(2), 8.22 +/- 1.12 mm, and 7.25 +/- 1.15 mm, respectively. The TM dimensions were increasing in fetuses between 20-32 weeks of gestation. However, the TM dimension was statistically similar at the 7th month, the 8th month and adult periods. The TM height was greater than its width in fetuses and adults. Conclusion The calculated regression equations of the TM parameters in fetuses may be used to estimate its size. The TM size did not change from the 7th gestational month, and thus the membrane reached adult diameter in fetal life. The TM height and width showed a very wide range; therefore, we thought that the 12 mm (the height) x 10 mm (the width) graft might be ideal dimension during the repair of the TM perforations.
Citation Count: 6
Evaluation of the stapedial tendon growth dynamic in human fetuses
(Springer France, 2019) Beger, Orhan; Koc, Turan; Karagul, Meryem Ilkay; Ozdemir, Deniz Ladin; Muduroglu, Fatma; Cintacioiu, Diana Georgiana; Talas, Derya Umit
PurposeThe main objective of the study was to investigate the morphometric properties of the stapedial tendon (ST) for pediatric otosurgeons and anatomists.MethodsThe present study was placed on 15 fetuses (8 females, 7 males) aged from 20 to 30weeks of gestation (at mean, 24.273.24weeks) using the collection of the Anatomy Department of Medicine Faculty, Mersin University. All measurements were obtained with a digital image analysis software.ResultsIn terms of male/female or right/left comparisons, no statistically significant difference was found in relation with the numerical data of ST. The surface area, length, and width of ST were detected as follows: 0.61 +/- 0.15mm(2), 1.27 +/- 0.30mm, and 0.45 +/- 0.08mm, respectively. The absence of ST was observed in two fetuses with and without severe malformations. In another fetus with cleft lip and polydactyly, multiple abnormalities were bilaterally identified in the middle ear: (1) the absence of the incudostapedial joint and (2) the presence of an abnormal tissue attaching to the stapes. The abnormal tissue was determined to be irregular dense connective tissue using light microscope and electron microscope.ConclusionOur findings showed that ST did not proportionally grow according to increasing gestational weeks. In the light of the numerical data, we thought that similar to stapes, ST attains the adult size in the fetal period. As ST anomalies may accompany severe malformations (e.g., cleft lip, polydactyly or syndactyly) that can be easily detected on observation by clinicians, we suggest that the detailed examination of middle ear in newborns should be taken into account for early diagnosis of conductive hearing loss to prevent any management delays.
Citation Count: 1
Growth Pattern of the Tympanic Ring in Human Fetuses
(Aves, 2021) Beger, Orhan; Vayisoglu, Yusuf; Ors, Alev Bobus; Ozdemir, Deniz Ladin; Muduroglu, Fatma; Taghipour, Pourya; Talas, Derya Umit
OBJECTIVES: The study aimed to display the growth pattern of the tympanic ring in fetal cadavers of 20-30 weeks of gestation. METHODS: In the study, 32 temporal bones of 16 fetuses (8 males, 8 females) of 24.62 +/- 3.44 weeks of gestation were dissected to measure the height (TRH), width (TRW), and perimeter (TRP) of the annulus, and the width (TNW) of the opening part of the annulus at the level of the tympanic notch. RESULTS: The TRH, TRW, TRP, and TNW were measured as 8.25 +/- 1.04 mm, 7.64 +/- 1.08 mm, 24.93 +/- 3.40 mm, and 4.01 +/- 0.91 mm, respectively. The parameters were similar at the seventh and eighth months of gestation; therefore, there was no variation from the seventh month. Linear function was calculated as y = 1.328 + 0.281 x weeks (P <.001) for the TRH, y = 1.284 + 0.258 x weeks (P <.001) for the TRW, y = 3.367 + 0.876 x weeks (P <.001) for the TRP, and y = -0.603 + 0.188 x weeks (P <.001) for the TNW. CONCLUSION: The parameters (TRH, TRW, TRP, and TNW) did not alter from the seventh month in utero. The linear functions (which represent the growth pattern of the parameters) of the tympanic ring may be useful for ear professionals to guess the annulus diameters, and to diagnose growth retardation and probable congenital anomalies in utero during sonographic imaging.