Browsing by Author "Selcuk, Emre"

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Citation Count: 0
Intraoperative Tissue-Immunosuppressive Therapy Reduces Rejection Episodes in Heart Transplant Recipients
(Baskent Univ, 2022) Rabus, Murat Bulent; Cekmecelioglu, Davut; Ata, Pinar; Salihi, Saleh; Selcuk, Emre; Balkanay, Mehmet
Objectives: Our study was conducted to determine the effects of intraoperative antithymocyte globulin administration on donor hearts procured after cardiocirculatory death. We evaluated the impact of antithymocyte globulin on graft function and related parameters during isothermic blood cardioplegia.Materials and Methods: In this prospective and randomized single center study, 30 patients with orthotropic heart transplant were divided into 2 groups: group 1 included 15 patients who received retrograde antithymocyte globulin infusion via coronary sinus intraoperatively and immediately after organ procurement and group 2 included 15 patients who received traditional antithymocyte globulin infusion after implantationResults: Study patients had a mean age of 33.8 years (range, 15-56 y). All patients had panel reactive antibody less than 10% except for 3 patients. The cluster of differentiation 3-positive cell count decrease was more than 20%. The inotropic therapy dose required and the myocardial pressure (stiffness) were less for group 1 patients. These patients had less acute rejection episodes than group 2 (0% vs 13.3%; P < .05).Conclusions: Favorable clinical outcomes were observed in terms of less acute rejection episodes and better graft function at least during the early posttransplant period. Intraoperative antithymocyte globulin treatment may have a preventive effect for acute cellular rejection in heart transplant patients.
Citation Count: 7
You Mean the World to Me: The Role of Residential Mobility in Centrality of Romantic Relationships
(Sage Publications inc, 2022) Kent Bırık, Oya; Selcuk, Emre; Gunaydin, Gul; Cingoz-Ulu, Banu; Filiztekin, Alpay; Kent, Oya
Integrating the suffocation model of marriage with research on residential mobility, the current studies examined for the first time whether long-term romantic relationships are more central for residentially mobile (vs. stable) individuals (total N across three studies = 5,366; age range = 18-95). In Study 1, individuals who moved away from their place of birth (vs. not) were more likely to first confide in their spouse over other network members on important matters. In Study 2, history of frequent residential moves was associated with greater importance ascribed to romantic partners in the attachment hierarchy. In Study 3, the slope of perceived partner responsiveness predicting eudaimonic well-being got steeper as residential mobility increased. By showing the role of residential mobility in romantic relationships, our findings highlight the importance of studying socioecological factors to gain a deeper understanding of how relationship processes unfold.