Browsing by Author "Senol, Kazim"

Now showing 1 - 4 of 4

Citation Count: 5
Clinical Features and Short-Term Outcomes of Bariatric Surgery in Morbidly Obese Patients: Institutional Experience at a Rural Hospital
(Mary Ann Liebert, inc, 2021) Senol, Kazim; Ferhatoglu, Murat Ferhat; Kocaeli, Aysen Akkurt; Dundar, Halit Ziya; Kaya, Ekrem
Objective: To prospectively evaluate the postoperative morbidity, mortality, and weight loss evolution of patients who underwent a bariatric procedure during 1 year of follow-up. Methods: Since July 2016, a total of 101 patients' data have been prospectively registered in a database. Comorbidities, operating time, hospital stay, early and late complications rate, and weight loss evolution after 1 year of follow-up were recorded. Results: The mean age was 38.41 +/- 11.05 years with a mean body mass index (BMI) of 49.02 +/- 5.89 kg/m(2) (range 38-67). Laparoscopic sleeve gastrectomy (LSG) was performed in 93 patients (92.07%) and Roux-en-Y gastric bypass (RNYGB) in 8 patients (7.92%). Thirty-day morbidity rate was 7.92% (8/101). Within a mean 9.32 +/- 2.25 (range 1-19) months follow-up time, mean percent of the excess of weight loss of 1st, 6th, and 12th months were 22.7 +/- 6.1, 67.2 +/- 11.2, and 81.4 +/- 10.5, respectively. Diabetes (n = 38, 37.6%), hypertension (n = 13, 12.9%), and obstructive sleep apnea (n = 5, 4.9%) were resolved in 76%, 68.4%, and 100% of the patients, respectively (p < 0.001). Conclusions: LSG and RNYGB are safe and highly effective, particularly in patients with a BMI >50 kg/m(2). Both techniques have been presented with better clinical outcomes regarding significant comorbidity resolution in the early evolution of weight loss.
Citation Count: 1
Clinicopathologic and Prognostic Features in Gallbladder Malignancies: Retrospective Analysis of 5206 Cases
(Galenos Yayincilik, 2019) Ferhatoglu, Murat Ferhat; Gürkan, Alp; Kivilcim, Taner; Kartal, Abdulcabbar; Gurkan, Alp; Genel Cerrahi / General Surgery
Aim: Gallbladder cancer is the sixth most common cancer of the gastrointestinal system. Clinical presentation may not be distinguished from cholelithiasis or cholecystitis and most patients are diagnosed intraoperatively or in the postoperative histologic examination. In this study, we aimed to investigate the association of incidentally detected gallbladder cancer with gallbladder premalignant lesions, age, gender, ultrasonography features and gallbladder stones. Methods: Demographic and clinical characteristics and pathology results of 5206 patients who underwent cholecystectomy between January 2012 and December 2015 were evaluated retrospectively. Results: Three thousand eight hundred and eighty four (74.6%) patients were female. Pathologic reports showed pre-malignant and malignant lesions in 102 (1.95%) cases. Metaplasia was significantly more common in females, while no significant difference was found in development of dysplasia and cancer between genders. Gallbladder stone was found to be a risk factor for the development of metaplasia. Gallbladder wall thickening and advanced age are the most important risk factors for gallbladder cancer. Conclusion: Female gender and gallstone are important risk factors for the development of metaplasia. Advanced age, gallstone and gallbladder wall thickening on ultrasonography are the most important factors in the development cancer. Cholecystectomy should be kept in mind as the most effective method to prevent cancer development in elderly patients with gallbladder stones.
Citation Count: 4
The Positive Effects of the Human Amniotic Membrane on the Healing of Staple Line After Sleeve Gastrectomy Applied Long-Evans Rat Model
(Springer, 2019) Ferhatoglu, Murat Ferhat; Kivilcim, Taner; Senol, Kazim; Vural, Gurcan; Kartal, Abdulcabbar; Incir, Said; Kebudi, Abut
Background The staple line leakage is a dangerous complication of sleeve gastrectomy. Various strategies have been tried to reduce the leakage risk. The amniotic membrane (AmM) is the inner layer of the placental membranes and has anti-inflammatory, anti-fibrosis, and anti-scarring effects, and it also has lower immune characteristics which are another essential characteristic of AmM concerning its utility for grafting. In this study, we aimed to investigate the impact of AmM on the staple line healing process of sleeve gastrectomy model in rats. Materials and Methods We used twenty-eight Long-Evans rats in this study. Sleeve gastrectomy was performed with tristapler. Fourteen rats served as controls, AmM was applied staple line of the other fourteen. Fourteen animals were sacrificed (seven from the AmM applied group and the other seven from the control group) on the third postoperative day. And, the other fourteen animals were sacrificed (seven from the AmM applied group and seven from the control group) on the seventh postoperative day. The tissue around the staple line was evaluated microscopically and macroscopically, bursting pressures and hydroxyproline levels were also measured. Results The bursting pressure and hydroxyproline measurements of the AmM applied group was significantly higher on the seventh postoperative day (p = 0.015, p = 0.012) Fibroblast activity and neoangiogenesis of the AmM applied group was also significantly higher on the seventh postoperative day (p = 0.004, p = 0.002). Conclusion This study showed that covering of staple line of sleeve gastrectomy model in rats significantly provided higher bursting pressures and increased hydroxyproline levels, fibroblast activity, and neoangiogenesis which may potentially lead a better staple line healing. We think further investigations are needed on this issue.
Citation Count: 8
Skin Metastasis of Renal Cell Carcinoma: A Case Report
(Springernature, 2018) Ferhatoglu, Murat F.; Senol, Kazim; Filiz, Ali I.
Metastasis of renal cell carcinoma is seen in approximately 25% of all cases. Rarely, they can appear in unusual sites. Herein, we present a 40-year-old female patient with an itching scalp mass. The mass appeared one year after the nephrectomy performed for a right renal cell carcinoma. Computed tomography scans have not identified any metastasis during the postoperative evolution of the disease. We excised the mass with a large surgical margin under local anesthesia. Pathological examination of the lesion diagnosed metastasis of clear cell carcinoma. Our case is not just the rare metastatic site but also the fact that the tumor appeared despite its low grade (T2N0MO). Unfortunately, the prognosis of metastatic renal cell carcinoma (RCC) with skin metastasis is in most cases unfavorable. We believe that our case could add more information to the following measures, complete the frame of rare oncologic cases and consolidate the data published on the topic so far. Although skin metastases are a poor sign of progression, disease-free follow-up is possible after appropriate surgical excision.