Altunkaynak, Berrin Zühal
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Name Variants
Berrin Z. Altunkaynak
Berrin Zühal, Altunkaynak
Altunkaynak, Berrin
ALTUNKAYNAK Berrin Zühal
Altunkaynak, Berrin Zühal
Berrin Zühal ALTUNKAYNAK
Altunkaynak, Zuhal
Altunkaynak Berrin Zuhal
Altunkaynak, B.
Altunkaynak Berrin Zühal
B. Zühal Altunkaynak
B. Z. ALTUNKAYNAK
ALTUNKAYNAK Berrin Zuhal
Berrin Zühal Altunkaynak
Zuhal Altunkaynak B.
Berrin Zuhal Altunkaynak
B. Zuhal Altunkaynak
Altunkaynak B.
Altunkaynak, Zühal
B. Z. Altunkaynak
Berrin Zuhal ALTUNKAYNAK
Altunkaynak, Z.
Altunkaynak, B. Z.
Altunkaynak, Berrin Zuhal
Altunkaynak,B.Z.
Berrin Zühal, Altunkaynak
Altunkaynak, Berrin
ALTUNKAYNAK Berrin Zühal
Altunkaynak, Berrin Zühal
Berrin Zühal ALTUNKAYNAK
Altunkaynak, Zuhal
Altunkaynak Berrin Zuhal
Altunkaynak, B.
Altunkaynak Berrin Zühal
B. Zühal Altunkaynak
B. Z. ALTUNKAYNAK
ALTUNKAYNAK Berrin Zuhal
Berrin Zühal Altunkaynak
Zuhal Altunkaynak B.
Berrin Zuhal Altunkaynak
B. Zuhal Altunkaynak
Altunkaynak B.
Altunkaynak, Zühal
B. Z. Altunkaynak
Berrin Zuhal ALTUNKAYNAK
Altunkaynak, Z.
Altunkaynak, B. Z.
Altunkaynak, Berrin Zuhal
Altunkaynak,B.Z.
Job Title
Prof.Dr.
Email Address
zuhal.altunkaynak@okan.edu.tr
Main Affiliation
Histoloji ve Embriyoloji / Histology and Embriology
Status
Website
ORCID ID
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
Scholarly Output
31
Articles
28
Citation Count
0
Supervised Theses
0
5 results
Scholarly Output Search Results
Now showing 1 - 5 of 5
Article Citation - WoS: 5Citation - Scopus: 4Effect of Luteolin on Biochemical, Immunohistochemical, and Morphometrical Changes in Rat Spinal Cord following Exposure to a 900 MHz Electromagnetic Field(Chinese Center Disease Control & Prevention, 2020) Yahyazadeh, Ahmad; Altunkaynak, Berrin Zuhal; Histoloji ve Embriyoloji / Histology and EmbriologyObjective This study aimed to investigate the effect of exposure to a 900 MHz electromagnetic field (EMF) on the cervical spinal cord (CSC) of rats and the possible protective effect of luteolin (LUT) against CSC tissue damage. Methods Quantitative data were obtained via stereological, biochemical, immunohistochemical, and histopathological techniques. We investigated morphometric value, superoxide dismutase (SOD) level, and the expression of high-mobility group box 1 protein molecules, as well as histological changes. Results The total number of motor neurons in the EMF group significantly decreased in comparison with that in the control group (P < 0.05). In the EMF + LUT group, we found a significant increase in the total number of motor neurons compared with that in the EMF group (P < 0.05). SOD enzyme activity in the EMF group significantly increased in comparison with that in the control group (P < 0.05). By contrast, the EMF+LUT group exhibited a decrease in SOD level compared with the EMF group (P < 0.05). Conclusion Our results suggested that exposure to EMF could be deleterious to CSC tissues. Furthermore, the protective efficacy of LUT against SC damage might have resulted from the alleviation of oxidative stress caused by EMF.Article Citation - WoS: 15Citation - Scopus: 18Biochemical, immunohistochemical and morphometrical investigation of the effect of thymoquinone on the rat testis following exposure to a 900-MHz electromagnetic field(Elsevier Gmbh, 2020) Yahyazadeh, Ahmad; Altunkaynak, Berrin Zuhal; Kaplan, Suleyman; Histoloji ve Embriyoloji / Histology and EmbriologyLong-term use of cell phones emitting electromagnetic fields (EMFs) have raised concerns regarding public health in recent year. We aimed to investigate the possible effects of 900 MHz EMF exposure (60 min/day for 28 days) on the rat testis. Another objective was to determine whether the deleterious effect of EMF radiation would be reduced by the administration of thymoquinone (TQ) (10 mg/kg/day). Twenty-four male adult Wistar albino rats were randomly selected, then assigned into four groups as followControl, EMF, TQ and EMF + TQ. Testicular samples were analyzed using histological, stereological, biochemical and immunohistochemical techniques. Total numbers of primary spermatocytes and spermatids as well as Leydig cells were significantly decreased in the EMF group compared to the Control group (p < 0.05). In the EMF + TQ group, the total number of primary spermatocytes was significantly increased compared to the EMF group (p < 0.05). Superoxide dismutase (SOD) activity was significantly increased in the EMF group compared to the Control group (p< 0.05). Also, serum testosterone levels and wet weight of testes were significantly decreased in the EMF group compared to the Control group (p < 0.05). Our findings suggested that exposure to a 900 MHz EMF had adverse effects on rat testicular tissue and that the administration of TQ partially mitigated testicular oxidative damages caused by EMF radiation.Article Citation - WoS: 3Citation - Scopus: 2Protective effect of indole-3-carbinol on testis of a high fat diet induced obesity(Taylor & Francis Ltd, 2023) Tufek, Nur Hande; Yahyazadeh, Ahmad; Altunkaynak, Berrin Zuhal; Histoloji ve Embriyoloji / Histology and EmbriologyWe investigated the effects of obesity caused by a high fat diet (HFD) on rat testes and evaluated the possible protective effects of indole-3-carbinol (IND). We used 24 8-10-week-old 200 g male rats randomly assigned to 4 groups: non-obese control (NC), obese control (OC), non-obese IND group (NI), obese + IND group (OI). Testis samples were examined using stereological, immunohistochemical, biochemical and histological methods. The number of spermatogenic cells, Leydig cells, mean volume of testes and seminiferous tubules was significantly decreased in the OC group compared to the NC group, but these values were increased significantly in the OI group compared to the OC group. We found a significant increase in catalase and myeloperoxidase activities in the OC group compared to the NC group. In the OI group, catalase and myeloperoxidase levels were decreased compared to the OC group. TUNEL-positive cells also were increased in the OC group compared to the NC group (p < 0.05), but these were fewer in the OI group than the OC group. We found marked morphological changes in testicular tissues between the NC and OC groups, as well as between the OI and OC groups. We found that HFD induced obesity was detrimental to rat testes and that administration of IND ameliorated testicular changes caused by obesity.Article Citation - WoS: 13Citation - Scopus: 15Investigation of the neuroprotective effects of thymoquinone on rat spinal cord exposed to 900 MHz electromagnetic field(Elsevier, 2019) Yahyazadeh, Ahmad; Altunkaynak, Berrin Zuhal; Histoloji ve Embriyoloji / Histology and EmbriologyExposure to electromagnetic field in long-term use of cell phones has increased concerns about serious health problems. Our aim was to survey the possible effects of electromagnetic field radiation (60 min/day for 28 days) on the spinal cords of 12 weeks old rats. Further, we investigated whether the administration of thymoquinone (10 mg/kg/day) would protect the spinal cord tissue against the adverse effects of electromagnetic field or not. Twenty-four adult male Wistar albino rats were assigned randomly into four groups: control, electromagnetic field, thymoquinone and electromagnetic field + thymoquinone. The cervical spinal cords of all rats was evaluated using the stereological, biochemical and histological methods. The number of motor neurons were reduced in the electromagnetic field group compared to the control group (p < 0.05). Superoxide dismutase level was higher in the electromagnetic field group compared to the control group (p < 0.05). In the electromagnetic field + thymoquinone group, we found an increase in the number of motor neurons and decrease in superoxide dismutase activity compared to the electromagnetic field group (p < 0.05). Our histological findings also exhibit the remarkable architectural alterations. We speculated that electromagnetic field radiation induced the morphological and biochemical damage to the spinal cord tissue of rats. Administration of antioxidant, thymoquinone, also ameliorated such complications caused by electromagnetic field.Article Citation - WoS: 9Citation - Scopus: 9Neuroprotective efficacy of luteolin on a 900-MHz electromagnetic field-induced cerebellar alteration in adult male rat(Elsevier, 2020) Yahyazadeh, Ahmad; Altunkaynak, Berrin Zuhal; Histoloji ve Embriyoloji / Histology and EmbriologyThe adverse health consequences of exposure to electromagnetic field emitted from cell phone has recently raised public concerns worldwide. Also, the Global System for Mobile Communications (GSM) standard that operates in 900 MHz frequency is the most popular. Therefore, we aimed to investigate the adverse effect of exposure to 900 MHz EMF (1 h/day) on the cerebella of 12-week-old rats. We also evaluated the protective activity of luteolin (20 mu g/kg/day) against possible biological change in the cerebellar tissues exposed to EMF. Twenty-four male wistar albino rats were randomly assigned into four group of six rats: Control, EMF, EMF + luteolin, luteolin. Serological and biochemical analyses, as well as histopathological examination were performed on all cerebellar samples. We found that SOD (superoxide dismutase) level was significantly increased in the EMF group compared to the control group (p < 0.05). To the contrary, decreased SOD activity was detected in the EMF + luteolin group compared to control group (p < 0.05). The total number of Purkinje and granular cells was significantly decreased in the EMF group compared to the control group (p < 0.05). In the EMF + luteolin group, the total number of Purkinje and granular cells was significantly higher than the EMF group (p < 0.05). Histopathological evaluation also showed destructive damage to the architectures of cerebellar tissues. Our results suggest that exposure to EMF may cause cellular damage to the rat cerebellum. Further, the improvement of cerebellar damage may have resulted from antioxidant efficacy of luteolin by alleviating oxidative stress.
