Histomorphometric changes in the placenta and umbilical cord during complications of pregnancy
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Date
2018
Journal Title
Journal ISSN
Volume Title
Publisher
Taylor & Francis inc
Abstract
Pregnancy complications may cause morphological changes and circulation defects in the placenta, which may lead to morbidity and mortality in fetuses and newborns. We investigated structural changes in the placenta and umbilical cord under various abnormal maternal conditions. Placenta and umbilical cord specimens were obtained from pregnant women during labor at 37 - 42 weeks gestation. Volumetric measurements were made for each placenta and umbilical cord using the Cavalieri method. Significant differences were observed for volumetric densities of total villi, syncytial knots, intervillous vessels and perivillous fibrin deposition. We observed particular increases in the volumetric parameters of the pre-eclampsia group compared to the other groups. The tunica media of the umbilical arteries was increased significantly with intrahepatic cholestasis.
Description
Keywords
apoptosis, morphometry, placenta, pregnancy complications, stereology, umbilical cord
Turkish CoHE Thesis Center URL
Citation
10
WoS Q
Q4
Scopus Q
Q3
Source
Volume
93
Issue
3
Start Page
198
End Page
210