Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
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Article Citation - WoS: 4Citation - Scopus: 4Abstract Elliptic Equations with Integral Boundary Conditons(Shanghai Scientific Technology Literature Publishing House, 2016) Shakhmurov, VeliThis paper focuses on nonlocal integral boundary value problems for elliptic differential-operator equations. Here given conditions guarantee that maximal regularity and Fredholmness in L-p spaces. These results are applied to the Cauchy problem for abstract parabolic equations, its infinite systems and boundary value problems for anisotropic partial differential equations in mixed L-p norm.Article Citation - Scopus: 0Accelerated Alkali-Silica Reaction After a Seven-Year Asr-Dormancy Period(Kare Publishing, 2024) Beglarigale, A.The ongoing alkali-silica reaction (ASR) in concrete can be halted by dryness, which is important for repairing ASR-suffered concrete structures. Drying of the concrete establishes an ASR-dormancy period until the end of the dryness. The residual expansion of such concrete after the ingress of water—the end of the dormancy period—is a significant risk, especially for repair works. In this experimental study, the post-dormancy expansion of various mixtures prepared by eight different Portland cement and three different supplementary cementitious materials (SCM) were tested using an accelerated mortar bar test. After accelerated ASR expansions, an ASR-dormancy period was established by keeping the specimens dry for seven years; the residual ASR expansions of the specimens were tested by the same accelerated meth-od. The effect of pre-dormancy reactions on the residual expansions was discussed through two perspectives. The post-dormancy expansion behavior of mixtures without or with insufficient SCM indicated that expansions were primarily driven by the swelling of old gel, whereas in specimens with sufficient SCM, the dominant mechanism was new gel formation, a result of lower pre-dormancy expansions due to the ASR-mitigating effect of SCMs. © 2024, Kare Publishing. All rights reserved.Article Citation - WoS: 3Citation - Scopus: 3Accuracy of the Anatomic Placement in Ultrasonography Guided Facet Joint Blockage with Supervising of C-Arm Fluoroscopy(Briefland, 2019) Erdogan, Sinan; Okur, Sibel Caglar; Atici, Aysegul; Gokcen, Huseyin Bahadir; Polat, Baris; Atici, YunusBackground: Facet joint blockage is a type of regional anesthesia which is performed selectively on the medial branch of the ramus dorsalis of the spinal nerve and is a current approach for the treatment of pain originating from facet arthropathy. This current approach to chronic low back pain caused by facet joint pathology is usually performed with ultrasound guidance. Objectives: The accuracy of anatomical placement of the facet joint with ultrasonography guidance is determined by C-arm fluoroscopy image taken as reference. Patients and Methods: A total of 22 patients who were diagnosed with facet joint syndrome were involved in the study. After detecting the superolateral corner of the facet joint, which is the target point with ultrasound, the control was provided with C-arm fluoroscopy by giving radiopaque fluid. In order to verify the localization, a mixture of 40 mg triamcinolone and 1 cc 2% lidocaine was injected. Results: Nerve blockage was applied to 67 facet joints at L3 - L4, L4 - L5 and L5 - Si level in a total of 22 patients (15 female and seven male) diagnosed with facet joint syndrome. The patients' mean age was 63 (range, 48 - 80), the mean body mass index was 28.4 (range,18.9 -38.1) and the mean time to determine facet localization with ultrasonography (USG) was 240 seconds (range,140 -320). Patients' mean visual analog scale (VAS) decreased from 7 (range, 6 - 9) to 2.5 (range, 1- 6). In the C-arm fluoroscopy control after the injection of radio-opaque material, the needle was found to be located in the lamina in four segments and it was relocated. In addition to this, two facet joints were not localized in ultrasound. This study concluded that the location of the facet joint with USG guidance is possible with 91% sensitivity and 100% positive predictive value when C-arm fluoroscopy was regarded as a gold standard in determining facet joint localization. No complications were observed. Conclusion: The results showed that ultrasonography guided facet joint block can be considered as a minimally invasive procedure that could be easily applied without radiation exposure.Article Citation - WoS: 6Citation - Scopus: 6Adverse Effect of Emotional Eating Developed During the COVID-19 Pandemic on Healthy Nutrition, a Vicious Circle: A cross-sectional descriptive study(Asoc Espanola Dietistas Nutricionistas, 2021) Ozcan, Burcu Ates; Yeslikaya, BurcuIntroduction: Because of the new type of coronavirus disease (COVID-19) seen worldwide, many countries have a difficult time both in terms of health and economy. It is thought that infection and fear of death owing to the disease may cause a disturbance in the individuals' psychology. Moreover, precautions such as social distancing and quarantine to prevent the spread of the disease and the prolongation of these interventions may further aggravate the conditions, such as mood disorders and stress. This study was aimed to determine the emotional eating status of individuals during the COVID-19 pandemic and to determine its effect on a healthy eating attitude. Material and methods: This is a cross-sectional descriptive study with a total number of 578 adults without COVID-19 diagnosis and treatment (422 [73%] women, 156 [27%] men). The study was conducted using the Google Forms web survey platform. The link to the survey was shared via WhatsApp and Instagram. The participants were asked to share the study link to reach out to as many potential participants as possible throughout the nation using the method known as snowball sampling. A questionnaire form which includes sociodemographic characteristics, the Turkish version of the Emotional Eater Questionnaire (EEQ-TR), and the Attitude Scale for Healthy Nutrition (ASHN) were applied to the participants. EEQ-TR and ASHN forms were answered twice, retrospectively for the pre-COVID period and prospectively during the COVID period. Results: While average emotional eating scores increased compared to pre-COVID-19 scores, individuals shifted from low-level emotional eaters to emotional eaters (p < 0.000). On the other hand, the average ASHN scores decreased, and individuals shifted from the middle-level healthy eating attitude to a low level (p < 0.000). As the quarantine period increased, emotional eating, body weight, and body mass index (BMI) increased, and healthy eating attitude decreased (p < 0.05). Conclusions: Individuals' emotional eating increased due to social distancing, self-quarantine, or isolation in the COVID-19 pandemic. These changes are found to be effective in healthy eating in a negative way. Long-term unhealthy eating is not recommended for people's health. Therefore, it is necessary to inform individuals about stress management, healthy nutrition, the importance of regular exercise, and sleep patterns.Article Citation - Scopus: 0AI Integrated Theoretical/Organic Chemistry is Set to Revolutionize the Future of Education and De Novo Drug Discovery(Science and Education Publishing Co. Ltd, 2024) Agar, S.; Tokay, I.; Akkurt, B.; Gokoluk, E.; Akbulut, M.B.; Ozler, B.D.; Elmas, M.This article discusses the rapidly expanding artificial intelligence (AI) tools combined with theoretical and organic chemistry software to point out the fact that near future is being reborn with a new education system and research system in drug discovery. The integration of AI into the field of chemistry and pharmacy has expanded rapidly in recent years. There has been a significant surge in both journal articles and patents, particularly from 2015 onward. Analyzing the distribution of these publications across various pharmaceutical and chemical research domains reveal that theoretical chemistry, organic chemistry and biochemistry have embraced AI most extensively, showing the highest growth rates. Utilizing such new software tools in educational research centers and academia, students and scholars can learn and apply much more long-durational and larger techniques in shorter times to yield massive results for the sake of humankind’s future with no diseases. This new type of educational and research-oriented technique integrating the control and check mechanism of AI is being used today for the design of new drugs which are essential for the longevity. The utilization of AI with in-silico studies and education increases the ability to stop diseases with a logarithmic increase while the old-fashioned ways of chemistry will be no more in the near future. Overall, this research paper offers a comprehensive overview of AI's advancement in pharmaceutical and chemical area and sheds light on its potential future trajectories. © The Author(s) 2024.Article Citation - WoS: 0Citation - Scopus: 0ALGINATE-BASED CELL ENCAPSULATION USING DIFFERENT CROSSLINKER ELEMENTS(World Scientific Publ Co Pte Ltd, 2024) Acar, Ozge Karabiyik; Tuncer, A. Alperen; Sahin, Fikrettin; Kose, Gamze Torun; Aysan, Erhan; Genetik ve Biyomühendislik / Genetic and Bio-EngineeringAlginate microcapsules are the most frequently used materials for cell transplantation. Different crosslinkers affect crosslinking affinity, which has a significant influence on microcapsule properties. The objective was to prepare in vitro microcapsules using calcium, barium, iron, manganese, nickel, and strontium as divalent cations to observe their potential for use in cell transplantation. Sodium alginate was added dropwise to the individually prepared crosslinkers to observe diffusion-based gelling. Alginate microcapsules were investigated regarding capsule stability, physiological properties, and cell viability. After 30 days of incubation, cell viability was greater than 90% for the cell-encapsulated microcapsules when crosslinked with CaCl2 and NiCl2. Viability decreased in the following order: CaCl2 > NiCl2 > BaCl2 > SrCl2 > MnCl2 > FeCl2. A compression test was performed to investigate the required force to deform 30% of microcapsules, and only MnCl2, FeCl2 (180mM), and NiCl2 (50mM) demonstrated higher resistance to the applied force than CaCl2. Except for the FeCl2 group, all cell-encapsulated microcapsules remained intact for 45 days. Potential sensitivities to CaCl2 during cell transplantation may compel alternative crosslinker usage, and our study revealed that NiCl2 and BaCl2 can be used as alternative crosslinkers to CaCl2 due to their high cell viability and consistent stability.Article Citation - Scopus: 4Analysis of effect of in-wheel electric motors mass on passive and active suspension systems(Asian Research Publishing Network, 2015) Omar,A.A.A.; Özkan,B.This study presents evaluation of effect of in-wheel electric motors mass on the performance of passive and active suspension systems using matlab. Linear Quadratic Regulator (LQR) is one of more common control methods which is used to complete the design of the active suspension system in this paper. Unsprung mass is one of the important parameters which effects on road holding and ride comfort behaviors in the vehicles, this effect obtained in this work by comparing the performance of the two systems using standard tire and tire with In-Wheel Electric Motor. Also, modeling and simulation of quarter car model completed to construct the Simulink models of the systems using MATLAB software. The study summarized bad effect of increasing the weight of tires by add In-Wheel Motors to the passive and active suspension systems on the road traction and the vehicles drivers comfort, at the same time the active suspension system with in-wheel motor needs high actuator force to work compared to the same system without in-wheel motor. © 2006-2015 Asian Research Publishing Network (ARPN).Article Citation - Scopus: 0Analysis of morphological parameters in pelvic radiography and hip MRI: A practical reporting recommendation(ARSMB-KVBMG, 2021) Cicek,E.D.; Cevik,H.Although numerous criteria have been proposed to define abnormal hip morphology, mostly used in the diagnosis of femoroacetabular impingement, it is not a practical approach to measure all of these parameters in all cases without clinical suspicion. In this study, our aim was to develop an evaluating and reporting standardization for routine hip examinations to define both hip morphology and impingement. A total of 108 patients with routine hip magnetic resonance imaging (MRI) and antero-posterior pelvic radiograph (PR) were included in this retrospective study. Alpha angle (AA), acetabular depth (AD), acetabular protrusion, acetabular anteversion, collodiaphyseal angle (CDA), lateral center-edge angle (LCEA) and Tönnis angle (TA) were measured. The differences and associations between these parameters were evaluated according to imaging modality or plane, and sex. Although a significant difference has been found between the axial AA and the coronal AA mean values measured on MRI, there was also a strong correlation. Coronal measurements were significantly higher. AA values measured in PR and coronal MRI were comparable. Males had higher AA in both planes as compared to females. There were no significant differences between CDA values in MRI and PR. There was a significant difference and a moderate correlation between AD values in MRI and PR. We suggest that routine reports should include a measurement of AA in two planes, and measurement of CDA in PR or MRI. Due to the difference in AD between MRI and radiography, LCEA or TA may represent better alternatives. Checking for a negative Tönnis sign would represent a practical approach. © 2021, Acta Orthopædica Belgica.Article Citation - Scopus: 0Analysis of Second-Order Linear Fuzzy Differential Equation Under an Innovative Fuzzy Derivative Approach and Its Application(World Scientific, 2024) Rangarajan, K.; Singh, P.; Salahshour, S.; Mondal, S.P.Fuzzy derivatives are a concept based on fuzzy calculus, which extends classical calculus to handle uncertainty and vagueness, habitually represented using fuzzy sets or fuzzy numbers. In fuzzy calculus, the derivative incorporates fuzziness, meaning both the input and output can have imprecise or uncertain values. In this paper, the step size is also considered as a fuzzy number. The impact of fuzziness in step size is studied here for first- and second-order fuzzy derivatives. Under this proposed derivative, differentiation of fuzzy exponential function is estimated. The concept is applied for solving second-order linear fuzzy differential equation. The proposed approaches are applied to spring mass system dynamics in fuzzy environment. Lastly, numerical illustrations on second-order fuzzy differential equations are shown using analytical technique and graphically the results are displayed. © World Scientific Publishing Company.Conference Object Citation - WoS: 0Citation - Scopus: 0Analysis of Under-Constrained and Unstable Structures by The Method TPO/MA(Amer inst Physics, 2018) Toklu, Yusuf Cengiz; Bekdas, Gebrail; Nigdeli, Sinan MelihUnder-constrained and unstable structures are those which are kinematically unstable. They may show large displacements even under very small forces contrarily to well-constrained stable structures. Under-constrained structures manifest themselves with insufficient boundary conditions. On the other hand, structures with missing members may become kinematically unstable under certain loadings. A common property of these structures is that the rank of their stiffness matrix, used in their analysis by classical methods, comes out to be zero, thus making impossible their analysis by these methods. Fortunately, application of the method Total Potential Optimization using Metaheuristic Algorithms (TPO/MA) makes the analysis of these structures very simple, with no extra difficulty as compared to the analysis of well-constrained stable structures. Examples shown in this study are demonstrating this fact.Book Part Citation - Scopus: 6Analytic network process with neutrosophic sets(Springer Verlag, 2019) Otay,İ.; Kahraman,C.Analytic network Process (ANP) can model the inner and outer dependencies and feedbacks between the decision-making elements in a network. It calculates the correct weights of criteria, and local and global priorities of alternatives in the presence of dependencies and feedbacks. Classical ANP is a multicriteria decision making method under certainty. However, it can be used under neutrosophic uncertainty. This chapter develops a neutrosophic fuzzy ANP method and illustrates its usage and validity through the solution of a supplier selection problem in a firm manufacturing automobile spare parts. © Springer Nature Switzerland AG 2019.Article Citation - WoS: 0Citation - Scopus: 0Analytical Modeling of Counter-Current Drying Process(int Center Applied thermodynamics, 2024) Pamuk, M. T.In this analytical study, spray drying of detergent particles of diameters 0.4-1 mm by using counter -current air heated at around 300 C-degrees is investigated using Matlab (c) . Particle drying using hot gases is a mature process with a vast variety of applications ranging from dried food to powdered detergent production. The study shows a strong relationship between the drying process (final water content) and particle size, drying gas temperature, as well as the tower dimensions since cross-sectional area of the tower has a direct control on vertical gas velocity, thus heat and mass transfer coefficients while the height of tower is closely related to residence time of particles in tower which guarantees the targeted drying level. The conclusions of this study can be a guide to have a better set of drying parameters such as inlet temperatures and humidity/water content as well as exit temperatures and humidity/water content and valuable information on how these relate to heat energy consumption necessary to heat the air from atmospheric conditions to the desired drying gas temperature. It is also worth indicating that the measurement of the absolute humidity in tower exhaust is a good parameter to control the drying process in an effective way.Article Citation - Scopus: 0Anatomical and Morphometric Features of the Profunda Brachii Artery(Korean Association of Anatomists, 2024) Şanlıtürk, Y.N.; Zeybek, N.; Gayretli, Ö.; Öztürk, A.When the literature is examined, studies evaluating the profunda brachii artery (PBA) are limited as most studies only investigate the artery’s origin. In 44 upper extremities belonging to 24 human anatomical specimens, single and double PBAs were observed in 39 and five cases, respectively. In cases with a single PBA, the origin was the brachial artery (BA) in 35 cases and the posterior circumflex humeral artery in four cases. In cases with double PBAs, the artery’s origin was the BA. Morphometric measurements of single and double arteries originating from the first branch BA were evaluated separately and compared according to sex and side. Our study, in which the PBA was examined morphologically and morphometrically, contributes to the literature anatomically and radiologically in treating humerus fractures and lateral arm-flap applications by surgeons. Copyright © 2024. Anatomy & Cell Biology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.Article Citation - Scopus: 0The antidepressant-like effects of kisspeptin-10 are reversed by kisspeptin antagonist peptide 234 in male rats(Cellular and Molecular Biology Association, 2024) Serhatlioglu, I.; Kacar, E.; Yardimci, A.; Ertugrul, N.U.; Bulmus, O.; Ercan, Z.; Kelestimur, H.; Fizyoloji / PhysiologyKisspeptins are reported to be the most potent activators of the hypothalamus-pituitary-gonadal (HPG) axis known to date. Kisspeptin potently elicits gonadotropin-releasing hormone (GnRH) release and luteinizing hormone (LH) secretion, even in the pre-pubertal period. Beyond the hypothalamus, kisspeptin is also expressed in limbic and paralimbic brain regions, which are areas of the neurobiological network primarily implicated in emotional behaviors alongside sexual functions. Therefore, an increasing body of studies has implicated kisspeptin as having many influences on emotional behaviors. The study was set out to explore if the kisspeptin/GPR54 signaling system is required for the anti-depressant-like effect of kisspeptin-10 (KP-10), besides the regulation of the HPG axis. To test this concept, peptide 234 (P234), a kisspeptin antagonist, was given to the male rats, and its modulatory effect on the anti-depressant-like effects of kisspeptin was investigated by using a forced swimming test (FST). The study has also sought to know whether kisspeptin can exert its effects through adrenergic and serotonergic receptors. To investigate this, the agents yohimbine (Yoh), an alpha-2 adrenergic receptor antagonist, and cyproheptadine (Cry), a non-selective 5-HT2 serotonergic receptor antagonist, were administered in the experiments. Our results indicate that, in rats, the anti-depressant-like effects of KP-10 in a modified rat FST are mediated by GPR54 receptors since the kisspeptin antagonist peptide 234 reversed kisspeptin-induced anti-depressant-like effects. Our data also demonstrate that the antidepressant-like effects of kisspeptin, at least in part, are mediated by an interaction of the alpha-2 adrenergic and 5-HT2 serotonergic receptors. © 2024 Cellular and Molecular Biology Association. All rights reserved.Article Antioxidant Activity, Chemical Composition, and Therapeutic Activity of Essential Oils From Certain Lamiaceae Species in Turkiye(Marmara Univ, Fac Pharmacy, 2024) Goksu Surucu, Canan; Dumlupinar, Berrak; Gurbuz, Burcak; Seker Karatoprak, Gokce; Bahtiyarca, Reyhan; Ilgun, SelenThe study examined the antioxidant, antimicrobial, and potential anticancer properties of lavandin (Lavandula x intermedia 'Grosso'), oregano (Origanum vulgare 'Ulu & gbreve; Bey'), and sage (Salvia officinalis 'Beyhekim') essential oils (EOs). Chemical analysis revealed that oregano is rich in carvacrol (81.23%), cymene (5.51%), and 18cineole (2.13%). Sage contains notable quantities of alpha- thujone (17.47%), camphor (13.59%), and borneol (12.14%). Lavandin is predominantly composed of linalool (41.10%), linalyl acetate (16.66%), and camphor (10.01%). The antimicrobial tests demonstrated that lavandin EOs exhibited a high inhibition rate of 90.77% at 1000 pg/mL, which subsequently decreased with lower concentrations. The oregano essential oils demonstrated robust antimicrobial activity across all concentrations, with a 10.97% inhibition rate observed even at the lowest concentration. The sage EOs exhibited a rapid decline in antimicrobial activity, reaching 4.97% at the lowest concentration. Both the DPPH and ABTS assays demonstrated that the antioxidant capacity of the essential oils was concentration-dependent. The cytotoxicity values of oregano essential oil were 35.58 at 50 pg/mL, 32.39 at 25 pg/mL, and 30.92 at 12.5 pg/mL. Similar cytotoxicity results were observed for sage and lavandin essential oils. These findings indicate that plant essential oils exert a dose-dependent cytotoxic effect on cell growth, significantly inhibiting cells at high concentrations. The research indicates that essential oils derived from Lamiaceae plants exhibit robust antimicrobial effects against a range of pathogens, suggesting potential applications as alternative therapies for specific microbial infections, comparable to ciprofloxacin at certain concentrations.Conference Object Citation - Scopus: 0Assessment of 5-6 Years Old Children's Perception of Environmental Awareness & Environmental Protection(2013) Ozyaral, O.; Karakaya, M.; Kaya, E.; Tıbbi Laboratuvar Teknikleri / Medical Laboratory TechniquesThe aim of this study was to identify and assess the perception of environmental awareness and protection among preschool children (4-5-6 years old), and develop education programs accordingly. To that end, we carried out a survey that consisted of 46 questions by means of face to face question-answer method. To create environmental consciousness and raise awareness of environmental protection at an early age, it is very important to make a proper assessment of answers given to the questions about the role of education in the creation of environmental awareness and environmental protection, when and how such education should take place, and from where such education should be received to achieve higher efficiency. In this context, the answers to the aforementioned questions will help us develop healthy methods to create environmental consciousness, raise realistic, permanent awareness of environmental protection, and instill good habits. The subjects of the study were 37 children, who were attending research-based preschool institutions resident in the districts of Ki{dotless}zi{dotless}ltoprak-Erenköy on the Anatolian Side of Istanbul. The children were at the same time attending regular preschool institutions. Within the scope of the study, we identified the parents' level of education as well as the children's perception levels about environment and environmental pollution (air pollution, water pollution, noise pollution, soil, and recycling), information sources, lifestyles, and habits. The study revealed that, along with the parents' educational background, the education received from preschool institutions and mass media play a significant, efficient role in the creation of environmental consciousness and awareness of environmental protection among children, and that we need to develop more efficient means of education. © SGEM2013 All Rights Reserved by the International Multidisciplinary Scientific GeoConference SGEM.Review Citation - Scopus: 0Assessment of association of serum lactate level with retinopathy of prematurity(Gazi Eye Foundation, 2021) OZATES,S.; KABATAS,E.U.; DILLI,D.; ZENCIROGLU,A.Purpose: To assess the relation between serum lactate level and development and progression of retinopathy of prematurity (ROP). Material and Methods: This retrospective study included premature newborns that received intensive medical care. Serum lactate levels that were obtained with three-day intervals during the fi rst month after birth was noted. Patients with ROP were included in ROP group and patients without ROP were included in control group. Results: 71 patients were included in ROP group and 35 patients included in control group. Mean gestational age 27.8 ± 1.8 weeks in ROP group and 28.7 ± 3.2 weeks in control group (p=0.061). Mean birth weight was 1150.4 ± 251.7 and 1262.3 ± 323.9 grams in ROP and control groups respectively (p<0.078). Mean serum lactate level at the fi rst day after birth was 36.6 ± 22.3 mg/dl in ROP group and 24.9 ± 12.8 mg/dl in control group (p<0.001). Mean serum lactate level at the fi rst month after birth was 26.6 ± 7.9 mg/dl in ROP group and 18.1 ± 6.5 mg/dl in control group (p<0.001). No signifi cant relation was observed between lactate level at the fi rst day and month and ROP stage and plus disease (p>0.05). Mean serum lactate level equal or over 21.2 mg/dl at the fi rst month predicted the development of ROP with a 76% sensitivity and 74% specifi city (Area under the curve: 0.837, p<0.001). Conclusion: Higher serum lactate levels were found associated with ROP and serum lactate level could be used to predict the development of ROP. © 2021 Gazi Eye Foundation. All rights reserved.Article Citation - WoS: 1Citation - Scopus: 2Assessment of IL-7RA T244I Polymorphism as a Risk Factor of Multiple Sclerosis in Turkish Population(Turkish Neuropsychiatry Assoc-turk Noropsikiyatri dernegi, 2020) Unsal, Mirac Aysen; Manukyan, Nuket Yildiz; Isik, Nihal; Direskeneli, Guher SaruhanIntroduction: The T244I variant of the IL-7RA gene, rs6897932, is one of the first polymorphisms found to be associated with the development of multiple sclerosis (MS). Although several studies provided evidence for the association of MS and this variant, other studies could not confirm this result. These inconsistent results suggest that the role of this polymorphism in the development of disease is associated with ethnicity. Methods: We investigated rs6897932 polymorphisms in a large cohort of patients with MS and healthy controls in a turkish population. Results: In our study, there were no significant differences in genotype frequencies in the IL-7RA rs6897932 polymorphism and no significant difference between C and T alleles in patients with MS and controls. Conclusion: This study is the first to evaluate the risk of the rs6897932 polymorphism in turkish patients with MS.Article Citation - Scopus: 0Assessment of Nursing Students' Attitudes and Awareness Towards Professional Research and Development;(AVES, 2020) Dincer,S.; Eker,O.; Deniz,Y.; Karacay,P.; Yazici,O.; Hemşirelik / NursingObjective: To assess nursing students' attitudes and awareness towards research and development and determine the affecting factors. Material and Methods: This study had a descriptive and correlational design. In total, 182 nursing students studying in two foundation universities in Istanbul participated in the study. Data were collected using the sociodemographic characteristics form and the nursing students' attitudes and awareness towards research and development scale. Results: The mean age of the nursing students was 20.91±1.93 years, 80.2% were women, 30.2% were first-year students, and 64.3% were Anatolian high school graduates. A total of 60.4% of the students stated that they did not take any course on research, 79.7% stated that they did not have any research experience, 72.5% stated that they did not follow scientific publications, 46.2% stated that they did not read scientific journals, and 63.7% stated that they did not receive training on how to access evidence-based information. The mean score of the students on the scale was 128±16.0. A significant statistical difference found between the students' total score on the scale and their sex, research experience, frequency of following scientific publications and reading scientific journals, and thinking of the educated to access evidence-based information (p<0.05). Conclusion: It was determined that nursing students were aware of research and development and had positive attitudes. Nursing students should be given training on how to access scientific knowledge in their undergraduate education, be asked to use evidence-based information in their assignments and be encouraged to participate in the nursing faculty research projects. © 2020 Archives of Health Science and Research. All rights reserved.Article Citation - Scopus: 0Assessment of Processed Meat Consumption in Children (6 -10 Years Old): Sample of an Elementary School in Istanbul, Turkey;(Asociacion Espanola de Dietistas-Nutricionistas, 2022) Karata,B.; Kusumler,A.S.Introduction: Processed meat has undesirable effects on overall diet quality especially in children and adolescents because the high consumption could increase the prevalence of obesity, cardiovascular disease, diabetes, and cancer. This study was carried out to evaluate the processed meat consumption of children (between 6-10 ages) and to observe their parents' attitudes on processed meat consumption and purchasing. Material and methods: This cross-sectional study was conducted with 297 parents whose children were in the 1st to 4th classes of an elementary school in istanbul. Children processed meat consumption and parents' opinion about processed meat, attitudes during shopping were analyzed. Chi-square, Spearman correlation, Kruskal Wallis (Tamhane) analyses were applied with Statistical Package for the Social Sciences (SPSS). Results were assessed in 95% confidence interval (CI) and p < 0.05 significance level. Results: The parents' first attitude during shopping was expiration date. The price tag on the package was the last attitude. Body Mass Index (BMI) of children and processed meat consumption wasn't related statistically (p>0.05), but increasing age was statistically related to higher processed meat consumption (p<0.05). Parents of children who believe in the adverse effect of processed meat consumed less (p<0.05). Conclusions: Most of the parents decreased processed meat consumption because of its adverse health effect. Parents prepared lunch boxes and preferred homemade food for their children. While the educational level of parents decreased, the amount of processed meat consumption of children increased. © 2022 Asociacion Espanola de Dietistas-Nutricionistas. All rights reserved.