Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14517/19

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  • Article
    The Impact of Channel Edge Type on the Particle Diffusion and Permeability of Carbon Nanotubes as a Membrane in Reverse Electrodialysis Process Using Molecular Dynamics Simulation
    (Elsevier Ltd, 2025) Li, X.; Ali, A.B.M.; Abbood, H.A.; Singh, N.S.S.; Al-Bahrani, M.; Abduvalieva, D.; Baghaei, S.
    Thermal energy storage with phase change materials offers effective solutions for energy management by absorbing and releasing thermal energy during phase transitions. Integrating nanoparticles, like gold, enhances thermal conductivity, modifies phase change characteristics, and boosts energy storage capacity. These advancements are valuable in renewable energy, precise thermal management, and high-efficiency energy storage, fostering innovation and sustainability in thermal science. This study investigates the effects of adding gold nanoparticles to paraffin-based phase change material, analyzing thermal property changes through molecular dynamics simulations to assess improvements in heat storage and energy efficiency. The results show that the carbon nanotube structure with the armchair edge was used to achieve the maximum electric current in the sample. Due to the strong interactions among carbon atoms in the armchair-edged carbon nanotube structure, the interaction between the fluid and the AC decreased. Also, the interaction between the base fluid and the channel wall varied with the edge type of carbon nanotubes. Based on the results, maximum electric current was achieved with a carbon nanotube featuring an armchair edge. © 2025 Elsevier Ltd
  • Article
    Lost Axillary Markers After Neoadjuvant Chemotherapy in Breast Cancer Patients - Data From the Prospective International AXSANA (EUBREAST 3) Cohort Study (NCT04373655)
    (W.B. Saunders Ltd, 2025) Hartmann, S.; Banys-Paluchowski, M.; Berger, T.; Ditsch, N.; Stickeler, E.; de Boniface, J.; Nowecki, Z.I.
    Introduction: Marking metastatic lymph nodes before neoadjuvant chemotherapy (NACT) has become increasingly popular in the surgical treatment of breast cancer. A variety of devices are currently in use. However, the significance of lost markers is poorly understood, and their impact on clinical decisions is unclear. Materials and methods: Among participants enrolled in the prospective AXSANA cohort study, those planned for target lymph node biopsy (TLNB) or targeted axillary dissection (TAD) with completed post-NACT locoregional therapy (surgery and radiotherapy) by January 21, 2025, were included. Results: In 88 of 1528 patients (5.8 %), axillary markers could not successfully be removed during surgery after NACT. The lost marker rate differed depending on the marker type (metallic clip/coil 7.0 %, carbon 3.1 %, radar reflector 1.4 %, magnetic seed 0.6 %, radioactive seed 0.0 %, p < 0.001). Additional postoperative imaging was performed in 25 (28.4 %) and further surgery to remove axillary markers was performed in 6 (6.8 %) patients with lost markers. The proportion of patients undergoing axillary lymph node dissection (46.6 % versus 36.5 %, p 0.069) and axillary radiotherapy (51.1 % versus 50.2 %, p 0.748) did not differ between patients with and without lost markers. After an average follow-up of 21.8 months, axillary recurrences occurred in 3 patients (3.3 %) with and 16 patients (1.0 %) without lost markers (rate ratio 2.89, p 0.088). Conclusion: The loss of markers in TLNB/TAD is uncommon and significantly depends on the marking technique. Lost markers may lead to diagnostic uncertainties and additional imaging or surgical procedures. © 2025 The Authors
  • Article
    Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry
    (2025) Aydın, M.N.; Şükür, E.Y.; Karaman, G.E.; Kaya, E.
    The aim of this study was to evaluate the impact of various polishing methods on the color stability of compomer and composite resin restorations used in anterior restorations within pediatric dentistry. One hundred and twenty disc-shaped specimens (8 mm diameter x 4 mm thickness) were prepared from A2 shade compomer and nanohybrid composite resin to assess color stability in four different polishing systems. Sixty specimens from each material were randomly distributed into five groups (n = 12) according to the polishing method used. Group 1: four-step aluminum oxide discs, Group 2: aluminum oxide discs and rubber kit, Group 3: aluminum oxide discs and felt discs, Group 4: aluminum oxide discs and spiral wheels, and Group 5: no polishing. The specimens were immersed in cherry juice solution for 7 days. The color changes (ΔE) for all materials were assessed using a spectrophotometer at baseline and after 7 days of staining. The collected data were analyzed with the Shapiro-Wilk test, along with the Mann-Whitney U test for comparing two independent groups and the Kruskal-Wallis test for comparing three or more independent groups. Post hoc Bonferroni Corrections were applied to identify the groups causing the differences. As a result of the analyses, statistically significant differences were determined between the staining measurements of the compomer and composite materials across the groups (p < 0.05). The highest level of discoloration for the compomer was in the control group. In conclusion, the selected polishing method influences the degree of discoloration in the compomer groups. In the composite group, polishing methods showed variable effects. Differences were found between the compomer and composite groups. Understanding these effects is crucial for maintaining the esthetic longevity of restorations in young patients.
  • Book Part
    Smart Guider on Historical Game Journey: Smart Scepter Design With Design Thinking Approach
    (IGI Global, 2025) Halaç, H.H.; Önaçan, M.B.K.; Önel, T.
    Transferring cultural heritage to younger generations plays an important role in shaping and guiding the future of societies. In this context, the “Historical Game Journey (HGJ)” project, which is based on Information Technology (IT) infrastructure, was developed to transfer historical knowledge and cultural heritage awareness to young generations through gamification. The aim of this study is to design and develop a smart scepter as a prototype that will help children find targets during the tour within the scope of HGJ's IT infrastructure. Three different designs were prepared using the Design Thinking Approach, and the most suitable one was selected by conducting a survey with the students who will use the scepter. The scepter and the developed IT infrastructure can be utilized, with minor adjustments, in museums, orienteering competitions, tourist areas, and military campuses. Additionally, it is anticipated that the database created by tracking the smart scepter will contribute to smart city applications. © 2025 by IGI Global Scientific Publishing. All rights reserved.
  • Article
    The Nexus Among CO2, Renewable Energy, Agricultural Production and Financial Development: Empirical Evidence From China and India
    (Econjournals, 2025) Çelik, R.A.
    This study examines the relationship between CO2, Renewable Energy, Agricultural Production and Financial Development for the 30-year period of 1993-2022 in China and India. The data for our variables, CO2 and Renewable Energy, were obtained from the official website of the World Bank, the Agriculture data from the official website of the Food and Agriculture Organization of the United Nations, and the Financial Development data from the official website of the International Monetary Fund. Our article was evaluated by empirical analyzes examining long-term and short-term relationships, as well as Multiple Regression Analysis, ADF and PP unit root tests, Johansen Cointegration test, VAR Analysis, Impulse Response analysis, Variance Decomposition analysis, FMOLS, DOLS and CCR analyzes. According to the analysis results, the model has a strong explanatory power of 99.48% in China and 99.54% in India. In addition, it was determined that agricultural activities increase CO2 emissions, while the use of renewable energy reduces emissions. It was observed that the effect of financial development on CO2 emissions was not statistically significant, but it could have indirect effects. Analyses conducted specifically for China and India revealed the strong effect of the agricultural sector on carbon emissions and emphasized that sustainable agricultural practices and green financing projects should be encouraged. In line with these results, supporting financial development with environmentally friendly policies, prioritizing green financing projects, and implementing incentives that will increase renewable energy use will contribute to controlling CO2 emissions in the long term. © 2025, Econjournals. All rights reserved.
  • Article
    Molecularly Imprinted Polymers (MIPS) in Wearable and Flexible Sensors: Advancing Healthcare Monitoring
    (Elsevier Inc., 2025) Zarepour, A.; Mohammadi Tabar, M.; Khosravi, A.; Jamalipour Soufi, G.; Hekmatnia, A.; Iravani, S.; Zarrabi, A.
    Molecularly imprinted polymer (MIP)-based wearable and flexible sensors have emerged as a groundbreaking technology in biomedical applications, offering highly selective and sensitive detection of biomarkers for real-time health monitoring as well as continuous tracking of critical health parameters such as glucose, lactate, stress hormones, etc. However, several challenges remain, including ensuring biocompatibility, complex biological environments, sensitivity, reproducibility and complexity of design, cost of production, detection limits, and clinical translation studies. The integration of these sensors into existing healthcare systems poses logistical hurdles such as data management and user acceptance. The materials used in the electronic components must be biocompatible to prevent adverse reactions when in contact with biological tissues or fluids. The prospects for MIP-based sensors are promising, with potential applications expanding into remote patient monitoring, telemedicine, and early disease detection. Herein, we aim to provide a comprehensive overview of the current developments surrounding MIP-based wearable and flexible sensors and their biomedical applications. This review aims to highlight recent advancements in sensor technology, including innovations in material science, sensor design, and integration with smart technologies, which have enhanced the sensitivity and specificity of these devices for real-time health monitoring. © 2025 Elsevier B.V.
  • Article
    Evaluation of Eating Attitude, Obsessive-Compulsive Symptoms, and Relationship Between Orthorexia Nervosa in Faculty of Pharmacy Students
    (Hacettepe University, Faculty of Pharmacy, 2025) Gizer, C.; Arslan, S.
    The objective of this study is to evaluate the relationships between eating attitudes, obsessive-compulsive symptoms, and orthorexia nervosa (ON) among pharmacy students. A cross-sectional study was conducted at Istanbul University with 332 pharmacy students, using ORTO-11, Maudsley Obsessive-Compulsive Inventory (MOCI), and Eating Attitude Test (EAT-40) scales. After excluding outliers, data from 323 participants were analyzed using SPSS 24.0. A significant negative correlation was found between EAT-40 and ORTO-11 scores (r =-0.405; p < 0.001), and MOCI sub-dimensions showed significant correlations with both EAT-40 and ORTO-11. Hierarchical regression analysis revealed that orthorexia nervosa significantly predicted eating attitudes, explaining 16.4% of the variance (F(1, 321) = 62.873, p < 0.05), while MOCI sub-dimensions did not significantly improve the model’s predictive power. Female students exhibited higher levels of orthorexia nervosa compared to males, consistent with literature suggesting that women are more prone to eating disorders and health-related anxiety. Students exhibited traits overlapping with obsessive-compulsive disorder (OCD), which may contribute to the development of eating disorders. The findings underscore the importance of addressing orthorexia nervosa and related obsessive-compulsive traits to promote healthier eating behaviors among pharmacy students. Educational programs that encourage balanced eating habits without excessive restriction can be developed, and students’ mental health can be supported through psychological counseling and awareness-raising initiatives. These measures may help mitigate the negative impacts of obsessive-compulsive traits and orthorexic tendencies in this population. © 2025, Hacettepe University, Faculty of Pharmacy. All rights reserved.
  • Article
    Investigation of the Atomic and Thermal Performance of Al2O3 Nanoparticles/Octadecane as Phase Change Materials (PCM) in Circular Tube With Molecular Dynamics Simulation
    (Elsevier Ltd, 2025) Yan, G.; Li, J.; Omar, I.; Salahshour, S.; Sabetvand, R.; Marzouki, R.
    Phase change materials' heat transfer mechanism may be enhanced by high thermal conductivity nanoparticles, allowing for quicker and more efficient thermal energy storage and release. This study examined the atomic and thermal characteristics of octadecane as a phase transition material inside a circular tube using molecular dynamics modeling with Al2O3 nanoparticles. At 0.031 (±0.002) atoms/Å3, the tube walls had the highest density after 20 ns. The tube's maximum recorded temperature was 751.51 (±1.01) K, and its peak velocity was 0.0078 (±0.0001) Å/fs. After 20 ns, the thermal conductivity was 1.35 (±0.01) W/m·K and the heat flux was 3.84 (±0.01) W/m2. The charging and discharging times of the structure were 6.45 (±0.05) and 7.15 (±0.03) ns, respectively. This study shows how AlO₃ nanoparticles can enhance the thermal performance of octadecane in energy storage applications. It also provided important information about the atomic-level behavior of these materials during phase transitions. © 2025 Elsevier Ltd
  • Article
    Search for Heavy Neutral Resonances Decaying To Tau Lepton Pairs in Proton-Proton Collisions at (Formula Presented)
    (American Physical Society, 2025) Hayrapetyan, A.; Tumasyan, A.; Adam, W.; Andrejkovic, J.W.; Benato, L.; Bergauer, T.; De La Cruz, B.
    A search for heavy neutral gauge bosons ((Formula presented)) decaying into a pair of tau leptons is performed in proton-proton collisions at (Formula presented) at the CERN LHC. The data were collected with the CMS detector and correspond to an integrated luminosity of (Formula presented). The observations are found to be in agreement with the expectation from standard model processes. Limits at 95% confidence level are set on the product of the (Formula presented) production cross section and its branching fraction to tau lepton pairs for a range of (Formula presented) boson masses. For a narrow resonance in the sequential standard model scenario, a (Formula presented) boson with a mass below 3.5 TeV is excluded. This is the most stringent limit to date from this type of search. © 2025 CERN, for the CMS Collaboration.
  • Article
    A Molecular Dynamics Approach To Investigate the Thermal Performance of Silica-Aerogel/PCM at Different Magnetic Field Frequencies
    (Elsevier B.V., 2025) Singh, N.S.S.; Rasheed, R.H.; Al-zahy, Y.M.A.; Al-Zahiwat, M.M.; Salahshour, S.; Hekmatifar, M.
    The significance of advanced energy storage methods is underscored by the increasing demand for renewable energy, which is a result of the need to reduce greenhouse gas emissions and the high cost of gas. Silica aerogels and phase change materials provide effective solutions for temperature regulation and thermal energy storage. This study examines the impact of magnetic field frequency on the thermal performance of a cubic silica aerogel/phase change material nanostructure that contained CuO nanoparticles. It capitalized on the superior thermal insulation properties of silica aerogels to enhance energy conservation and minimize environmental impact. The utilization of a molecular dynamic simulation enabled us to investigate the movement of heat between particles and their unique characteristics. The impact of various magnetic field frequencies on critical parameters, such as density, temperature, thermal conductivity, heat flux, and charging/discharging periods, was investigated through molecular dynamics simulations. The results indicate that the maximum density increased from 0.999 to 1.035 atoms/ų as the magnetic field frequency increased to 0.05 fs⁻¹. In contrast, the maximum velocity diminishes from 0.0092 to 0.0081 Å/fs, and the maximum temperature decreases from 762 K to 743 K. The heat flux and thermal conductivity diminish to 69.88 W/m² and 1.82 W/m·K, respectively, as the magnetic field frequency increases. It is important to note that the discharging time decreased slightly to 8.06 ns at a frequency of 0.05 fs⁻¹, while the charging time increased, reaching 7.12 ns. These findings underscore the potential of the combination of PCMs with silica aerogels to improve thermal management and energy storage applications through the application of magnetic fields. © 2025 Elsevier B.V.
  • Article
    Hydrovoltaic Energy Harvesting: a Systematic Review and Bibliometric Analysis of Technological Innovations, Research Trends, and Future Prospects
    (Elsevier Ltd, 2025) Odoi-Yorke, F.; Agyekum, E.B.; Tarawneh, B.; Rashid, F.L.; Nyarkoh, R.; Mensah, E.; Raza, M.A.
    The growing demand for sustainable energy solutions has positioned hydrovoltaic energy harvesting (HEH) as a promising renewable technology that converts water-based phenomena into electricity. Despite its potential, the field lacks a comprehensive synthesis of its research progress and technological evolution. This study addresses this gap through an integrated bibliometric and systematic review approach. Bibliometric analysis of 52 peer-reviewed articles, sourced via Scopus, reveals an exponential growth in HEH research from 2020 to 2024, driven predominantly by East Asian countries, with China leading the field. Key thematic clusters were identified using tools such as Bibliometrix and VOSviewer, highlighting innovations in materials like MXenes and nanostructured carbon and their role in enhancing energy conversion efficiency. A systematic review of the selected studies categorizes advancements in fundamental mechanisms, device architecture, and scalable applications. Notable findings include the development of flexible hydrovoltaic devices for wearable electronics and hybrid systems for integrated energy generation and storage. These advancements underline HEH's potential for addressing climate challenges and energy inequities, particularly in underrepresented regions like Africa and South America. The review highlights strategic investment priorities for HEH systems, including scaling, integrating hybrid technologies, and fostering global collaborations to accelerate HEH's transition to practical, scalable renewable energy systems. © 2025 The Author(s)
  • Article
    Measurement of the Higgs Boson Mass and Width Using the Four-Lepton Final State in Proton-Proton Collisions at (Formula Presented)
    (American Physical Society, 2025) Hayrapetyan, A.; Tumasyan, A.; Adam, W.; Andrejkovic, J.W.; Bergauer, T.; Chatterjee, S.; Josa, M.I.
    A measurement of the Higgs boson mass and width via its decay to two (Formula presented) bosons is presented. Proton-proton collision data collected by the CMS experiment, corresponding to an integrated luminosity of (Formula presented) at a center-of-mass energy of 13 TeV, is used. The invariant mass distribution of four leptons in the on-shell Higgs boson decay is used to measure its mass and constrain its width. This yields the most precise single measurement of the Higgs boson mass to date, (Formula presented), and an upper limit on the width (Formula presented) at 95% confidence level. A combination of the on- and off-shell Higgs boson production decaying to four leptons is used to determine the Higgs boson width, assuming that no new virtual particles affect the production, a premise that is tested by adding new heavy particles in the gluon fusion loop model. This result is combined with a previous CMS analysis of the off-shell Higgs boson production with decay to two leptons and two neutrinos, giving a measured Higgs boson width of (Formula presented), in agreement with the standard model prediction of 4.1 MeV. The strength of the off-shell Higgs boson production is also reported. The scenario of no off-shell Higgs boson production is excluded at a confidence level corresponding to 3.8 standard deviations. © 2025 CERN, for the CMS Collaboration.
  • Article
    Comparison of Apical Transportation and Canal Straightening Between Protaper Next, Hyflex, Reciproc and Reciproc Blue Instruments
    (Selcuk University, 2022) Türkyilmaz, A.; Erdoğan, D.; Akbal Dinçer, G.; Erdemir, A.
    Background: This study aimed to compare apical transportation and canal straightening of ProTaper Next, HyFlex Electric Discharge Machining, Reciproc and Reciproc Blue nickel-titanium (NiTi) files with different apical enlargements. Methods: Forty-eight mandibular molar human teeth were included in the study. The teeth were divided into four groups according to the NiTi file types (n=12). A digital radiographic method was used to compare apical transportation and canal straightening in the buccolingual and mesiodistal directions using before-and-after images superimposed with Image J software. The Kruskal-Wallis test with Bonferroni correction and the Wilcoxon test were used; the P value was set at 5%. Results: The maximum transportation of the buccolingual and mesiodistal directions were 0.216 mm and 0.196 mm with Reciproc file. The maximum straightening of the buccolingual and mesiodistal directions were degrees of 8.661 and 8.048 respectively with ProTaper Next and Reciproc files. Conclusion: ProTaper Next, HyFlex Electric Discharge Machining and Reciproc Blue filespresented similar results. Using a larger instrument increased the apical transportation and canal straightening. © 2022, Selcuk University. All rights reserved.
  • Article
    Toplum Yapay Zeka ile Dental Tanı Konmasına Hazır Mı?
    (Selcuk University, 2022) Güneç, H.G.; Gökyay, S.S.; Kaya, E.; Aydın, K.C.
    Background: This study aims to determine the perspective of Turkish society on preventive medicine and personalized healthcare practices with artificial intelligence-assisted dental diagnostic applications that are/will be put into use in dentistry practice. Methods: Our questionnaire, which was prepared with 29 closedended and 2 open-ended questions using a web-based questionnaire platform, was applied online to 307 people whose native language is Turkish. The questions of our questionnaire were prepared by two endodontists, one pedodontist, and one oral, dental, and maxillofacial radiology specialist dentist. The questions are under the headings of “oral-dental healthcare policies and literacy, preventive dentistry practices, access to dentists, oraldental healthcare and technology cooperation, artificial intelligence practices in dentistry. Results: % 78.2 of the respondents think that “healthcare activities do not reach all segments of the society”, % 44.6 think that “their knowledge of oral and dental healthcare is sufficient”, % 54.1 think that “they cannot benefit from preventive dentistry practices”, % 55.7 think that “prolongation of the dentist's time spent in dental diagnosis and diagnosis affects dental anxiety levels”, % 60.9 think that “they cannot access effective and accurate information from the Internet in oral and dental health problems they feel”, % 83.7 think that “artificial intelligence applications can be effective in dental diagnosis and diagnosis”, and % 93.8 think that “dentist and artificial intelligence can work together”. Conclusion: This study shows that new technologies should be used in dentistry while revealing the evaluations of the Turkish society on oral and dental healthcare. However, it reveals that artificial intelligence-based oral-dental healthcare practices should be used in dentistry practice and that such practices will play a role in the benefit of society in matters such as preventive medicine and dental healthcare tourism. © 2022, Selcuk University. All rights reserved.
  • Article
    Diş Hekimliğinde Fotopolimerizasyon ile 3 Boyutlu Üretim Yöntemleri ve Kullanım Alanları
    (Selcuk University, 2023) Özay, M.; Saridağ, S.
    In recent years with the rapid development of production technologies there has been a remarkable increase in the use of 3D printers. This technology, which is also used in the fields of aviation, defense, art and design, has an important place in dentistry. With many materials used with different methods, patient and dentist comfort is increased and working time is shortened. New production methods; contrary to traditional methods such as plaster model casting and orthodontic treatment with brackets, it has advanced the efficiency and success of treatments and has also enabled many new developments. Photopolymerized resins; in addition to the production of prosthetic base material, obturator, temporary crown-bridge, it is also used in the production of models in the field of dental education. The aim of this review is to provide an overview of the use of light-cured resins in the 3D production process. Also; it is aimed to give information about additive manufacturing technologies, materials used in these technologies, advantages and disadvantages. © 2023, Selcuk University. All rights reserved.
  • Article
    Molecular Dynamics Simulation of Thermal Behavior of Ammonia Refrigerant in the Presence of Copper Nanoparticles
    (Elsevier B.V., 2025) Ameen, H.F.M.; Ali, A.B.M.; Sadeq, A.S.; Singh, N.S.S.; Salahshour, S.; Baghaei, S.
    Nanofluids are mixtures of a base fluid and nanoparticles (also known as nano-scaled particles), and they were used within advanced heat transfer applications with known aggregation issues as well as unreliability in performance. Molecular dynamics simulations can effectively look at nanofluid behavior with no disruptions, especially when considering the complications and limitations involved with performing experiments at the nano-scale. We conducted molecular dynamics simulations that investigate the thermal and atomic behaviors of a nanofluid, which involved ammonia nanofluids with copper nanoparticles in aluminum nanochannels. Our results focused on evaluating the outflow of the nanofluid and on determining the primary factors including maximum velocity, temperature heat flux and nanoparticle aggregation time while modifying the initial conditions of temperature (300-350 K), and pressure (1-5 bar). Furthermore, we found the thermophysical properties of the nanofluids were heavily dependent on the initial temperature and pressure. By improving the initial temperature and pressure, thermal systems can support the promotion of efficiency and sustainability. We also measured the kinetic and potential energies, with the potential energies measuring -8399.15 eV and 80.69 eV after 5 ns with no indications of structural instabilities. The results indicated that as the initial temperature was increased, maximum velocity increased from 0.00086 to 0.00099 Å/ps and maximum temperature increased from 240 to 258 K. Furthermore, heat flux decreased from 1411 to 1397 W/m² and aggregation time decreased from 3.96 to 3.93 ns. On the other hand, maximum velocity decreased to 0.00078 Å/ps and maximum temperature decreased to 234 K, as well as heat flux increased to 1436 W/m² and aggregation time increasing time was increased to 4.07 ns, with the increasing initial pressure. These results provided some insight into the optimization of nanofluids for energy conserving thermal control, by varying operating conditions, and offered implications for sustainable engineering applications. © 2025 The Author(s)
  • Book Part
    Liposomes: Application in Drug Delivery and Cancer Therapy
    (Springer Science+Business Media, 2025) Nejati, O.; Saberi, G.; Madani, G.; Bal-Öztürk, A.; Zarepour, A.; Khosravi, A.; Zarrabi, A.
    Liposomes are lipid-based bilayer vesicles that have become promising tools for cancer therapy and drug delivery. They have structural similarity with cells and have the capability of encapsulating both hydrophobic and hydrophilic drugs that could improve the stability and bioavailability of therapeutic compounds. They can be engineered with various polymers, linkers, or targeting moieties to enhance their stability, minimize the off-target effects, improve their accumulation at targeted sites, enhance their therapeutic performance, and reduce the systemic toxicity. In this chapter, we have discussed these types of nanoformulations, their classification, different methods used for their preparation, and their applications in drug delivery and cancer therapy, with a particular emphasis on cancer immunotherapy. © Springer Nature Singapore Pte Ltd. 2025.
  • Erratum
    Retracted: Adaptation Challenges of Edge Computing Model in Educational Institute(Journal of Intelligent & Fuzzy Systems, (2025), 48, (491-508))
    (SAGE Publications Ltd, 2025) Momena, A.F.; Gazi, K.H.; Mukherjee, A.K.; Salahshour, S.; Ghosh, A.; Mondal, S.P.
    This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219434. © 2025 – IOS Press. All rights reserved.
  • Article
    The Effect of XP-Endo Finisher R and PIPS Technique Using Er: YAG Laser on Removal of Gutta-Percha in Root Canals Obturated With Two Different Obturation Techniques
    (Selcuk University, 2024) Akbal Dinçer, G.; Türkyilmaz, A.; Hançerlioğullari, D.; Ermiş, G.; Erdemir, A.
    Background: The purpose of this study is to compare the efficacy of XP-endo finisher R file and PIPS technique using Er: YAG laser on gutta-percha removal in root canals obturated with two obturation techniques. Methods: The root canals of sixty single-rooted teeth were prepared with ProTaper Next Rotary instruments up to X3 (Dentsply, Ballaigues, Switzerland). Half of the root canals were obturated with cold lateral condensation technique and the other half with System B technique (Kerr Corporation, CA, USA) and BioRoot RCS sealer (Setodent, Louisville, USA) was used in all groups as a root canal sealer. After one week, all samples were retreated with Protaper Universal retreatment instruments (Dentsply Maillefer, Ballaigues, Switzerland) and enlarged to ProTaper Next X5 File at the working length. Both groups were divided into 3 subgroups according to the additional cleaning methods: control group without an additional cleaning method, XP-endo Finisher R or PIPS technique using Er: YAG laser. Finally, all teeth were split longitudinally and images were taken using an operation microscope (Carl Zeiss, Heidelberg, Germany). The images were analyzed by Image J program. Two-way ANOVA and Tukey tests were used for statistical analysis. Results: There was a statistically significant difference between the canal filling techniques applied in the evaluation of remnants (p=0.010). There was no significant difference between additional cleaning methods (p=0.196). Conclusion: Within the limitations of this study, cleanliness is more difficult in root canals obturated with System B technique. Use of additional cleaning method was not effective in removal of root canal filling materials. © 2024, Selcuk University. All rights reserved.
  • Article
    Dental Students’ Anxiety Level, Awareness of Dental Anxiety, and Attitudes in Treating Patients With Dental Anxiety
    (Selcuk University, 2022) Aykol Şahin, G.; Özden, Z.T.; Altan Köran, S.M.
    Background: Successful treatment of patients with dental anxiety requires particular attitudes and knowledge. Dentists who have severe stress, inadequate knowledge, or less sensitivity to anxious patients may affect the success of the treatment. The aim of this study was to evaluate the general anxiety level and occupational perceptions of the final-year dental students and their attitudes to and knowledge level about anxious patients. Methods: The anxiety levels of the dental students were assessed by the Beck Anxiety Inventory. A questionnaire that evaluated professional perceptions, dental anxiety awareness, attitude, and knowledge level was conducted. The answers between the groups were compared, and differences were assessed statistically. Results: One hundred fifty-nine final-year dental students answered the questionnaire. No statistical difference was found between the anxiety levels of the students. 69,2% of students agreed that patients evaluate dentists with their style or behavior rather than their perceived technical competence. Female students and the students with adverse patient experiences perceived dentistry as a more stressful profession (respectively p=0,001, p=0,003). 39,6% of students had never taken a course related to dental anxiety. 25,8% of students thought that there is a relationship between dental anxiety and wound healing, and 37,1% of students thought that dental anxiety aggravates the inflammatory disease. Conclusion: The final-year dental students need more training in managing their stress and increasing their knowledge about anxious patients. There is a need for further studies involving dental anxiety management strategies with a higher number of dental students or dentists. © 2022, Selcuk University. All rights reserved.