WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14517/18

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Alternative Treatment for Refractory Jacquet Dermatitis After Hirschsprung Disease Surgery: a Case Report
(Elsevier, 2025) Kilic, Sinan; Guven, Ahmet; Isik, Sakine
Introduction: Jacquet's erosive diaper dermatitis (JDD) is a severe form of diaper dermatitis, characterized by papuloerythematous erosions with crater-like borders in the genital and perianal regions. Case presentation: A 2-year-old male patient was diagnosed with Hirschsprung disease (HD) during the neonatal period. A transition zone was detected in the rectosigmoid region on a contrast enema. Full-thickness rectal biopsy confirmed aganglionosis, and a colostomy was created from the transverse colon. At 18 months of age, the patient underwent the Swenson procedure, and the colostomy was closed during the same session. Following the operation, spontaneous stool passage was achieved. Approximately six months after surgery, ulcerative lesions characteristic of Jacquet dermatitis developed in the perianal region. Despite six months of treatment with moisturizers, regenerative, epithelializing, and barrier therapies (e.g., zinc oxide, madecassoside, shea butter, glycerin, oatmeal, hyaluronic acid), the lesions did not improve. However, after initiating treatment with pure Aloe Vera gel, including a 10 % diluted natural extract applied four times daily, plus a dairy-free diet for three weeks, a rapid clinical response was observed, with visible improvement within the same period. Conclusion: The combination of Aloe Vera-based ointment plus dairy-free diet seems to be an effective management strategy for children with post pull-through Jacquet's dermatitis.
Analysis and Implementation of Sensorless Pmsm Drive With Reduced Dc-Link Capacitance Under Parameter Variations
(Ieee, 2024) Sumsek, Reha Ozgur; Calik, Ramazan; Yavuz, Fikri Serkan; Kivanc, Omer Cihan
In AC drives used in heating, ventilation and air-conditioning applications, film capacitors are becoming widespread instead of electrolytic capacitors in DC-link. These drives with reduced capacitor value provide cost and volume advantages. However, dc-link oscillation increases due to the reduced capacity value. These oscillations cause instability, overvoltage and an increase in total harmonic distortion (THD). On the other hand, the winding temperatures of these motors, which operate continuously under rated operating conditions, reach 80 degrees C. The stator resistance and rotor flux value, which change with the increase in temperature, cause these drives, controlled without sensors, to operate even more unstable. In this study, a hybrid approach is proposed to improve the performance of the inverter using a 16 mu F film capacitor at the dc-link and to reduce the THD. The active damping method regulates the inverter output voltage for DC-link voltage stabilization. A permanent magnet synchronous machine (PMSM) sensorless speed control based on stator feedforward voltage estimation and a model reference adaptive system (MRAS) based on a multiparameter estimation algorithm is performed to minimize the effects of parameter variations. As a result of the experimental studies, it is observed that the grid input current complies with the IEC61000-3-2 standard, even under severe parameter variations.
Antioxidant Activity, Chemical Composition, and Therapeutic Activity of Essential Oils From Certain Lamiaceae Species in Türkiye
(Marmara Univ, Fac Pharmacy, 2025) Goksu Surucu, Canan; Dumlupinar, Berrak; Gurbuz, Burcak; Seker Karatoprak, Gokce; Bahtiyarca, Reyhan; Ilgun, Selen
The study examined the antioxidant, antimicrobial, and potential anticancer properties of lavandin (Lavandula x intermedia 'Grosso'), oregano (Origanum vulgare 'Ulu & gbreve; Bey'), and sage (Salvia officinalis 'Beyhekim') essential oils (EOs). Chemical analysis revealed that oregano is rich in carvacrol (81.23%), cymene (5.51%), and 18-cineole (2.13%). Sage contains notable quantities of alpha-thujone (17.47%), camphor (13.59%), and borneol (12.14%). Lavandin is predominantly composed of linalool (41.10%), linalyl acetate (16.66%), and camphor (10.01%). The antimicrobial tests demonstrated that lavandin EOs exhibited a high inhibition rate of 90.77% at 1000 pg/mL, which subsequently decreased with lower concentrations. The oregano essential oils demonstrated robust antimicrobial activity across all concentrations, with a 10.97% inhibition rate observed even at the lowest concentration. The sage EOs exhibited a rapid decline in antimicrobial activity, reaching 4.97% at the lowest concentration. Both the DPPH and ABTS assays demonstrated that the antioxidant capacity of the essential oils was concentration-dependent. The cytotoxicity values of oregano essential oil were 35.58 at 50 pg/mL, 32.39 at 25 pg/mL, and 30.92 at 12.5 pg/mL. Similar cytotoxicity results were observed for sage and lavandin essential oils. These findings indicate that plant essential oils exert a dose-dependent cytotoxic effect on cell growth, significantly inhibiting cells at high concentrations. The research indicates that essential oils derived from Lamiaceae plants exhibit robust antimicrobial effects against a range of pathogens, suggesting potential applications as alternative therapies for specific microbial infections, comparable to ciprofloxacin at certain concentrations.
Assessing Parents Perception of Environmental Awareness
(Stef92 Technology Ltd, 2013) Ozyaral, O.; Ayra, F.; Kaya, E.
It is inevitable to avoid from the influences of some adversities to arise in the ecosystem as "environmental risks" on our lives. The present study aims to determine the level of perception of parents on environmental awareness and environmental protection and to raise awareness on the environmental value and protection. In the present study, the questionnaires were administered to the parents of two private kindergarten students in Ki{dotless}zi{dotless}ltoprak-Erenköy districts on the Asian side of Istanbul as well as the parents of first and second grade students of a private primary school in Umraniye district on the Asian side of Istanbul. The parents of these first and second grade students and the kindergarten students were asked to fill in these questionnaires. A questionnaire prepared by the researchers and consisting of 76 questions was administered to the parents of the kindergarten students in order to measure their parents' environmental perception, 12 of which were prepared to measure the demographic characteristics and 64 of which were prepared for the perception measurement. In the study, the relations between the socio-economic and demographic characteristics of the parents and their environmental perceptions were tried to be found out. Moreover, to what extent the parents put into practice what they know was analyzed so that it can be shown how the information acquired affects the behavior acquisition. In line with the findings obtained, the fact that the awareness of the parents themselves on environment and ecosystem should be improved so that they can transfer the proper actions and approaches they have internalized to their children was found out. Emphasizing the environmental education in every part of the life and providing this education through non-governmental organizations and the experts and the efficiency of the media in this regard were among the results. In addition, the environmental awareness studies should begin during childhood for the sustainability of the environmental awareness education and the media studies should be heavily focused on so that the socio-cultural behavior changes could be ensured in the society and the social media studies should be made. © SGEM2013 All Rights Reserved by the International Multidisciplinary Scientific GeoConference SGEM.
Autoimmune Encephalitis and Musicogenic Epilepsy: a Case of Gad65 Antibody-Associated Seizure
(Wiley, 2025) Mohammadi-Asl, Ali; Bahadori, Amir Reza; Sabzgolin, Iman; Davari, Afshan; Razmafrooz, Mohammad; Tafakhori, Abbas; Ranji, Sara
Musicogenic epilepsy (ME) is a rare form of reflex epilepsy with a prevalence of 1 in 10,000,000. Recent research suggests a potential link between ME and autoimmune encephalitis, particularly involving glutamic acid decarboxylase 65-isoform (GAD65) antibodies. A 48-year-old female presented with a one-year history of music-triggered seizures. Her episodes were characterized by an initial aura followed by unresponsiveness and oral automatisms. Electroencephalography revealed abnormalities in the left anterior temporal lobe and temporal leads. Laboratory studies showed positive anti-GAD65 antibodies. The patient was treated with a combination of antiepileptic medication (Lamotrigine) and corticosteroids and intravenous immunoglobulin. This case contributes to the growing evidence supporting an association between ME and autoimmune mechanisms, particularly GAD65 antibody-mediated autoimmunity. It highlights the importance of screening autoimmune factors in ME patients and highlights the need for further research into targeted treatment strategies.
Capital: an Introduction To the Three Volumes
(Palgrave Macmillan, 2024) Savran, Sungur
Capital: the Book of Communism
(Palgrave Macmillan, 2024) Savran, Sungur
Comparative Analysis of Transaction Performance in Different Virtualization Environments
(Istanbul Univ, 2024) Candemir, Ali Ihsan; Incereis, Nilgun
Virtualization technologies are increasing in importance day by day. The selection of virtualization software is an important factor to realize efficient use of physical hardware. In this study, the Ubuntu 22.04 LTS operating system was run on VirtualBox, VMware, and Docker, which are widely used virtualization software. Then, the Tiobench, Compress-7zip, C-ray, Smallpt, Tachyon, and OSBench tests were performed on the Ubuntu operating system with the Phoronix Test Suite software, and the test results were analyzed and compared. The results demonstrate that Docker outperformed the other virtualization technologies, although not in every test. Owing to its rapid deployment and efficient use of resources, Docker is suitable for applications that require agility and scalability. However, traditional virtualization technologies, such as VMware, may be more suitable for applications that require high security and extensive resource management. In addition, this study provides information that can guide users in selecting virtualization software.
Comparison of Perioperative Outcomes and Urethral Complications Between Using 24-French and 26-French Resectoscope Sheaths in Holmium Laser Enucleation of the Prostate
(Galenos Yayıncılık, 2022) Yildiz, Ali; Akdemir, Serkan; Anil, Hakan; Guzel, Ahmet; Arslan, Murat
Aim: Although the 26F resectoscope is frequently used in transurethral prostatectomy, there are some concerns with high-caliber shafts. We compared 24F and 26F resectoscope used for Holmium Laser Enucleation of the Prostate (HoLEP) in terms of effects on postoperative urethral complications and perioperative outcomes. Methods: Data from patients undergoing HoLEP from 2017 to 2021 was retrospectively analyzed. All surgeries were completed by a single surgeon. The patients were divided into one of two groups according to the resectoscope diameter (24F or 26F). All patients were followed up for urethral complications for 12 months. Perioperative outcomes and urethral complications were compared between the groups. Results: The study included 301 patients. The mean age of patients was 68.5 +/- 8.3 and 69.1 +/- 8.6 for the 26F group (n=180) and the 24F group (n=121), respectively (p=0.608). A total of seven in the 26F group (3.8%) and 3 patients in the 24F group (2.4%) had postoperative urethral stricture (US) (p=0.503). Besides, 2 patients (26F) and 1 patient (24F) had postoperative bladder neck contracture (BNC) (p=0.807). The operation efficiency was 1.25 g/min in the 26F group and 1.17 g/min in the 24F group (p=0.005). Conclusion: The use of 24F or 26F RS was not shown to cause statistically significant differences in the incidence of US and BNC during the 12-month follow-up. The use of the 24F RS significantly reduces surgical and morcellation efficiency.
Comparison of Posterior and Antero-Lateral Renal Tumors in Retroperitoneal Laparoscopic Partial Nephrectomy: a Propensity Score Matching Analysis
(Codon Publications, 2023) Anil, Hakan; Yildiz, Ali; Guzel, Ahmet; Akdemir, Serkan; Karamik, Kaan; Arslan, Murat
This study aimed to compare the antero-lateral and posterior localized renal masses in laparoscopic partial nephrectomy with the retroperitoneal approach in terms of operative, functional, and oncological outcomes. Patients who underwent retroperitoneal laparoscopic partial nephrec-tomy by a single surgeon between January 2013 and January 2021 were included in the study. A one-to-one propensity score matching (PSM) analysis was conducted to obtain two balanced groups. The patients were divided into two groups as posterior and antero-lateral according to the localization of the mass. A total of 239 patients were included in the PSM analysis, with 65 patients allocated to each group. The mean operative time was 79.2 & PLUSMN; 11.2 min in the posterior group, while it was 90.0 & PLUSMN; 11.6 min in the antero-lateral group (P < 0.001). Warm ischemia time was 15.9 & PLUSMN; 2.4 min in the posterior group and 18.6 & PLUSMN; 2.7 min in the antero-lateral group (P < 0.001). The median decrease in eGFR at 1 year was 4.8 (IQR, 2.9-6.9) mL/min in the posterior group and 5.0 (IQR, 2.8-11) mL/min in the antero-lateral group (P = 0.219). The warm isch-emia time and clamping technique were found to be significant factors for predicting eGFR change after surgery (13:0.693, 95% CI: 0.39-0.99, P < 0.001; 13:6.43, 95% CI: 1.1-11.7, P = 0.017, respectively). We report that retroperitoneal laparoscopic partial nephrectomy provided longer warm ischemia and operative time for antero-lateral renal masses than posterior masses. However, long-term oncological and functional results were similar for both localizations.
Comparison of Three Different Modalities for the Treatment of Bladder Calculi by Size
(Sage Publications Ltd, 2022) Yildiz, Ali; Anil, Hakan; Erol, Ibrahim; Karamik, Kaan; Ercil, Hakan
Purpose: Treatment recommendations for kidney or ureteral stones are based on stone size; however, this is uncertain for bladder stones. This study aims to determine the best approach to bladder stones based on their size. Materials and methods: We retrospectively analyzed 401 patients with bladder stones. Patients were divided into three different groups according to stone size (11-20 mm, 21-30 mm, 31-40 mm as groups 1, 2, and 3 respectively). Patients had transurethral cystolithotripsy (TUCL), percutaneous cystolithotripsy (PCCL), and open cystolithotomy (OCL) performed. Results: Stone fragments were removed completely in all patients. When catheter time, postoperative stay, and hematocrit decrease values were compared, the results were significantly higher for OCL in all three groups (p: 0.001). When the relationship between stone sizes and operation time is evaluated, TUCL had shorter operation times (34.1 +/- 10.6 min) in group 1. However, TUCL had longer operation times in group 2 and group 3 compared to OCL and PCCL. Conclusion: TUCL may be preferable due to better postoperative outcomes and shorter operative time for <= 2 cm stones. As the stone size increases, PCCL is more favorable in terms of operation time.
Confusions Concerning Sraffa (and Marx): Reply To Critics
(Palgrave Macmillan, 2024) Savran, Sungur
The Controversy Between the Neo-Ricardians and the Marxists
(Palgrave Macmillan, 2024) Savran, Sungur
Critique of Political Economy
(Palgrave Macmillan, 2024) Savran, Sungur
(De)securitization of the Kurdish Issue in Turkey: the Nexus of Foreign Policy and Domestic Politics in the Twenty-First Century
(Palgrave Macmillan, 2023) Balaban, Gokce
Design of a Position Controlled Electric Actuator Used in Fluid Control Valves
(IEEE, 2016) Tosun, Gurkan; Kivanc, O. Cihan; Oguz, Ender; Mutlu, Yasar; Ustun, Ozgur
Valves are the main elements for controlling fluids in industry and other application areas. To control flow precisely, valves need a controlled action which leads to implement actuators, gear systems and electronic controllers. Increasing dominance of electrical actuators due to the advantages of easy control and intervention and space-efficient designs brings seldom implementation of hydraulic and pneumatic actuation. In fluid control applications, the main target is to obtain the right position, i.e. angle for rotary actuators, for adjusting flow rate. In this study, the design and implementation of a position controlled electrically actuated valve used for fluid control are presented. The design phases of system universal power supply and electronic control system are given and the experimental results of position control which are representing the validation the design study is also discussed. Also a special current control scheme is used to overcome transient disruptions.
Developed and Characterization of a Novel Cd Doped CeO2 Nanofilm and Application of Methyl Orange Removed by Photodegradation
(Springer, 2025) Söyleyici Çergel, M.; Demir, E.; Kurtaran, S.
Cerium oxide (CeO2) films doped with cadmium (Cd) were synthesized employing the ultrasonic spray pyrolysis technique (USP). The structural, surface, and optical properties of the prepared Cd-doped CeO2 films were also investigated. All films were polycrystalline, exhibiting as cubic fluorite structure. In addition, the optical bandgap obtained using the UV data ranged from 3.23 to 3.52 eV. Cd-doped CeO2 films exhibited Raman scattering, in which the multi-peak setting of the first optical longitudinal mode was observed, indicated the Raman shift of the characteristic peak in the ~ 461 cm−1 range. In addition, the photodegradation capacities of Cd-doped CeO2 films were investigated for the removal of pesticides that pollute human and environmental health. As a result, proposed Cd-doped CeO2 thin films show very high (approximate 80%) photocatalytic activity for removing important pollutants, such as methyl orange dyestuff. Consequently, the CeO2 film doped with Cd can be readily reused for five cycles without a notable alteration in photocatalytic activity. © Indian Association for the Cultivation of Science 2024.
Diagnosis and Treatment Approach of Children With Acute Gastroenteritis in a Tertiary Center: Medical Cost Analysis
(Galenos Publ House, 2023) Atici, Serkan; Dalgic, Buket
Introduction: Although there are well defined guidelines in the literature for diagnosis and treatment of acute gastroenteritis which is common diseases in children, most of time patients are not managed according to these guidelines and unnecessary tests and treatments are performed. The unnecessary tests and treatments costs account for a significant percentage of healthcare spending. We aimed to analyze the diagnostic and therapeutic cost of patients with acute gastroenteritis who admitted to the tertiary center in Turkey. Materials and Methods: A total of 342 patients, aged under 18 years were admitted to Gazi University Hospital and diagnosed with acute gastroenteritis were included to the study. The clinical features, diagnosis and treatment approach and medical costs of the patients were recorded and analyzed. The medical costs were calculated according to the bills which were sent to Social Security Foundation known as SGK. Results: According to the bills which were sent to SGK the mean total cost was calculated $22.99 +/- 13.40, the mean laboratory test cost was $11.14 +/- 9.72 and the mean cost of the treatment in the hospital was $2.64 +/- 6.21. 70% of testing cost and 90% of treatment cost were inappropriate according to the current guideline recommendation about diagnose and treatment of acute gastroenteritis. Conclusion: Health professionals, especially pediatricians, should aim to apply appropriate diagnostic and therapeutic approaches, taking into account current guidelines. In this way, it will be possible to reduce medical costs and avoid waste in acute gastroenteritis cases.
Diagnostic Value of Shear Wave Velocity in Polycystic Ovarian Syndrome
(Medical Communications, 2021) Gursu, Turkan; Cevik, Halime; Desteli, Guldeniz Aksan; Yilmaz, Birnur; Bildaci, Tevfik Berk; Eraslan, Alper
Aim: In polycystic ovarian syndrome, the ovaries become stiffer due to chronic anovulation. We aimed to compare tissue elasticity in terms of shear wave velocities measured using acoustic radiation force impulse imaging technique between the ovaries of polycystic ovarian syndrome women and non-polycystic ovarian syndrome women. Material and methods: The study was designed as a retrospective data analysis of women who underwent transvaginal ultrasound and acoustic radiation force impulse imaging in a university hospital between July 2014 and March 2015, for various reasons. There were 32 polycystic ovarian syndrome patients and 32 patients without a diagnosis of polycystic ovarian syndrome. Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, prolactin, antimullerian hormone levels, and menstrual patterns with clinical hyperandrogenism were evaluated. On the menstrual cycle days 2-4, by performing a transvaginal ultrasound scan, the ovarian volumes and antral follicle counts in both ovaries were recorded for each woman. The ultrasound system was converted into the elastography mode, and acoustic radiation force impulse imaging was performed. Shear wave velocity (m/sec) was measured at least 5 times for each ovary, and the mean value was calculated for each polycystic ovarian syndrome and non-polycystic ovarian syndrome woman. Results: Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, and prolactin levels were similar between the groups (p 0,05). Antimullerian hormone levels, antral follicle counts, and mean ovarian volumes were statistically different between the groups (p <0,05). Mean shear wave velocity values for both ovaries were 2.12 +/- 0.82 (0.78-4.9) m/sec in the polycystic ovarian syndrome group, and 1.18 +/- 0.41 (0.77-2.0) m/sec in the non-polycystic ovarian syndrome group, which was statistically significantly different (p = 0.016). Conclusion: In our study, we found significantly higher shear wave velocity levels in polycystic ovarian syndrome women than non-polycystic ovarian syndrome women, which indicates an impact of the condition on shear wave velocity. The increased acoustic frequencies cause a decreased response in time to transition, and motion becomes out of phase; in other words, scattered waves are faster in stiffer ovaries. Our results are thus compatible with the pathophysiology of the disease. Shear wave velocity is a beneficial tool for evaluating ovarian elasticity in polycystic ovarian syndrome patients in whom the levels are found to be significantly higher than non-polycystic ovarian syndrome women. In light of these findings, shear wave velocity is expected to be slower than polycystic ovarian syndrome levels in ovulatory women.
Diagnostic Value of Voiding Scores of the "International Prostate Symptom Score" and the "Bristol Female Lower Urinary System Symptoms-Short Form" Questionnaires in Women With Voiding Dysfunction
(Wolters Kluwer Medknow Publications, 2024) Erbay, Mehmet Erkan; Sevinc, Burcu Hanci; Tarhan, Fatih
Introduction:We aimed to investigate the diagnostic value of International Prostate Symptom Score voiding symptom score (IPSS-VS) and Bristol Female Lower Urinary Tract Symptoms-short form voiding score (BFLUTS-VS) in female patients with urodynamically diagnosed voiding dysfunction. Methods:The medical records of female patients who underwent urodynamic examination between May 2007 and November 2021 for lower urinary tract complaints were retrospectively evaluated. A total of 1858 female patients were included in the study. Patients investigated between 2007 and 2014 were asked to fill the IPSS, and patients investigated after 2015 were asked to fill the BFLUTS-SF. Results:The mean age of the patients was 49.06 0.33 in the IPSS group and 50.02 +/- 0.47 in the BFLUTS group. On the pressure flow study, voiding dysfunction was found in 14.8% (n = 95) in the IPSS group and 15.1% (n = 183) in the BFLUTS group. The area under curve value was found to be 0.58 for IPSS and 0.64 for BFLUTS. Threshold values were found as >9 for IPSS-VS and >4 for BFLUTS-VS. The sensitivity, specificity, false negative, and false positive rates for IPSS-VS were 33.3%, 78.8%, 66.7%, and 21.2%, respectively. The same parameters were 45.5%, 78.9%, 54.5%, and 21.1% for BFLUTS-VS, respectively. Conclusion:The diagnostic performance of both the questionnaires was found to be low for diagnosing voiding dysfunction in female patients according to our data. Therefore, the assessment of the voiding phase in women should not solely rely on the current questionnaires. However, further studies using questionnaires including all voiding symptoms are required.

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