WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14517/18

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Now showing 1 - 20 of 2339

Decidual Cell-Derived Interleukin-6 Inhibits Il11-Mediated Gene Expression in Macrophages: Implications for Preeclampsia
(Sage Publications inc, 2014) Kayisli, U. A.; Ocak, N.; Uyar, A.; Guzeloglu-Kayisli, O.; Basar, M.; Huang, J.; Lockwood, C. J.
Can the Right Brain Hemisphere's Rapid Sensory Processing Capability Speed Up the Reaction Time of the Left Hand
(Wiley, 2025) Karaoglu, Isinsu; Pinar, Lamia
Examining the Burnout of Audiologists in Türkiye Relationships With Quality of Work Life and Psychological Well-Being
(Amer Speech-Language-Hearing Assoc, 2025) Akbulut, Ahmet Alperen; Demirel, Aysenur Karaman; Sacli, Yeter; Satici, Sema; Ozcan, Ahsen Kartal; Ciprut, Ayca
Purpose: Although burnout among audiologists has been studied in various countries, there is no research yet that examines this issue in T & uuml;rkiye, where working conditions and sociodemographic factors may differ from those in other countries. Considering the unique working conditions and sociodemographic factors, this study aimed to investigate the burnout levels of Turkish audiologists. Additionally, this study will explore the impact of various sociodemographic variables on burnout, work-related quality of life, and depression to gain a deeper understanding of the specific challenges faced by audiologists in T & uuml;rkiye. Method: A total of 193 audiologists, with a median age of 27 (interquartile range: 25-29) years, working in different working areas, such as clinical practice, academic institutions, rehabilitation centers, and amplification services in T & uuml;rkiye, were included. Audiologists were invited to participate in this study via several online forums and hospital notice boards. All participants completed the sociodemographic data form and then the Maslach Burnout Inventory (MBI), Work- Related Quality of Life Scale (WRQoL), and Beck Depression Inventory (BDI). Results: Differences between MBI, WRQoL, and BDI scores were analyzed according to gender, level of education, area of work, and title of audiologist. There are significant differences in the subscale scores of the MBI and WRQoL scales and in the BDI scores between groups according to gender, education, and area of work. There are also significant differences in BDI scores according to title. There is a significant correlation between the MBI, WRQoL, and BDI scores of audiologists. Conclusions: This study represents the initial exploration of burnout, quality of work life, and depression levels among audiologists employed in T & uuml;rkiye. A low quality of work life can increase the risk of burnout and depression. Enhancements in the work environment can lessen burnout and depression while also improving employees' general quality of life.
Investigation of Trace Element and Toxic Metal Blood Levels in Obese Children
(Aves, 2025) Kilic, Sinan
Anatomical Relationship Between the Profunda Brachii Artery and the Radial Nerve at the Entrance and Within the Radial Groove
(Springer France, 2025) Sanliturk, Yusra Nur; Gayretli, Ozcan; Zeybek, Nursen; Ozturk, Adnan
PurposeIn this study, it was aimed to examine the relationship between the profunda brachii artery and the radial nerve at the entrance to and within the radial groove considering no comparable study was found in the literature.MethodDissection was performed in 44 upper extremities (21 right and 23 left) of 24 fixed cadavers used for medical education at Istanbul University, Istanbul Medical Faculty, Department of Anatomy.ResultsProfunda brachii artery was found to be a single artery in 39 extremities and a double artery in 5 extremities. In 27 cases with single PBA, the nerve was located superolateral to the PBA (Type A), and in 8 cases the nerve was located inferomedial to the PBA (Type B). In all 5 extremities with double profunda brachii artery, the proximal branch was superolateral (Type A) and the distal branch was inferomedial (Type B).ConclusionsThis research will support surgeons understanding how to better anatomically and radiologically treat humeral fractures and lateral arm flap applications.
Choroidal Vascularity Index Findings in Patients Recovered From Mild Course Covid-19 Pneumonia
(Springer, 2025) Toprak, Muge; Kesim, Enes; Karasu, Bugra; Celebi, Ali Riza Cenk
PurposeTo assess the choroidal vascularity index (CVI) in individuals who have recovered from moderate pneumonia caused by COVID-19, using enhanced depth imaging optical coherence tomography (EDI-OCT).MethodsThis study included 43 patients who had recovered from SARS-CoV-2 infection with mild pneumonia (Group 1-COVID group), as well as 45 healthy individuals (Group 2- healthy control group). The study comprised COVID-19 patients who fully recovered from COVID-19 pneumonia. These patients were assessed 6 months after their pneumonia had totally resolved. The measurements were acquired via EDI-OCT investigations of the choroidal structures. The primary measure of interest was the CVI, which is defined as the ratio of the luminal area (LA) to the total choroidal area (TCA).ResultsPatients from Group 1 (COVID group) who had totally recovered exhibited significantly higher mean TCA, stromal area (SA), and LA compared to patients from Group 2 (control or healthy group). The two groups did not show a significant difference in CVI (p = 0.080).ConclusionChoroidal vascularity index can reveal the choroidal vascular physiology in patients who have fully recovered from COVID-19 pneumonia. EDI-OCT can be utilized to evaluate choroidal vascular alterations, serving as a non-invasive indicator for early vascular impairment following SARS-CoV-2 infection.
The Stability of the Sars-Cov Structure in the Presence of Variable External Heat Flux in the Vicinity of the Water/Silver Nanofluid: a Molecular Dynamics Simulation
(Elsevier, 2025) Wu, Dongfang; Ali, Ali B. M.; Mohammed, Abrar A.; Alizadeh, As'ad; Salahshour, Soheil; Hashemian, M.; Wang, Mengxia
Changes in the dynamics and conformation of the SARS-COV-2 structure, which are usually brought on by external heat flux (HF), may have an impact on the structure's stability. For example, increased HF levels may cause the protein to unravel or denaturate, which may lead to a loss of functioning. By examining the impact of exogenous HF on the stability of SARS-COV-2 structure using molecular dynamics simulations, these complex mechanisms may be better understood, and the virus's capacity to adapt to different environments can be enhanced. This work investigated the effect of the varied HF frequency on the stability of the SARS-COV-2 virus in the proximity of a water fluid containing silver nanoparticles using molecular dynamics modelling. The SARS-COV-2 virus and silver-water nanofluid were shown to have the following properties: mean square displacement, diffusion coefficient, and interaction energy (IE) at HFs ranging from 0.01 to 0.1 ps-1. The results showed that the modeled samples' equilibrium phase occurred at 300 K. Furthermore, it was found that the generated nanofluid contained an inactivated copy of the SARS-CoV-2 virus. Numerically, the SARS-COV-2 sample's diffusion coefficient and IE converged to 0.3856 nm2/ps and 3037.83 kcal/mol, respectively. Furthermore, the results of the simulation suggested that setting the HF parameter to 0.01 fs-1 would result in a higher degree of degradation of the SARS-CoV-2 virus. These results are expected to improve the effectiveness of SARS-CoV-2 viral degradation procedures in clinical applications.
Mxenes in Combination Therapy: Chemo-Photothermal, Chemodynamic, and Photothermal/Photodynamic Therapies for Cancer Treatment and Antibacterial Applications
(Elsevier, 2025) Amoozadeh, Masoomeh; Zarepour, Atefeh; Khosravi, Arezoo; Iravani, Siavash; Zarrabi, Ali
Two-dimensional MXenes and their derivatives have attracted significant attention in recent years for their potential applications in combination therapies, specifically in chemo-photothermal, chemodynamic, and photothermal/photodynamic treatments. MXenes offer distinct advantages in combination therapies due to their exceptional electrical conductivity, hydrophilicity, large surface area, tunable surface chemistry, and ability to enhance drug delivery and therapeutic efficacy through multifunctional applications. By incorporating MXenes into combination therapies, researchers have demonstrated enhanced therapeutic efficacy through synergistic mechanisms that improve drug delivery, increase localized heating, and amplify the generation of reactive oxygen species, thereby effectively targeting and eliminating cancer cells or contaminations. However, stability in biological environments remains a primary concern, as degradation can compromise their therapeutic effectiveness and safety. Ensuring biocompatibility is crucial, since the introduction of MXenes and their composites may trigger immune responses or cytotoxicity. Moreover, optimizing the synthesis of high-quality MXenes with uniform properties remains a logistical challenge, affecting reproducibility and scalability for clinical applications. By consolidating existing knowledge and identifying future directions, this review aims to advance MXenebased combination chemo-photothermal, chemodynamic, and photothermal/photodynamic therapies for cancer treatment and antibacterial applications, ultimately paving the way for innovative strategies in biomedicine and personalized medicine.
Smart Mxene-Based Microrobots for Targeted Drug Delivery and Synergistic Therapies
(Royal Soc Chemistry, 2025) Iravani, Siavash; Zarepour, Atefeh; Khosravi, Arezoo; Varma, Rajender S.; Zarrabi, Ali
MXenes and their composites exhibit remarkable electrical conductivity, mechanical flexibility, and biocompatibility, making them ideal candidates for microrobot fabrication. Their tunable surface chemistry allows for easy functionalization, which enhances their interaction with biological environments, thereby facilitating targeted therapies. Such smart microrobots can be engineered to navigate through complex biological systems with precision via the integration of responsive elements, such as stimuli-sensitive polymers or magnetic components. MXene-based microrobots are able to actively seek out specific tissues or cells. This capability is crucial for applications in cancer treatment, where localized drug delivery minimizes side effects and enhances therapeutic efficacy. The primary advantage of MXene-based microrobots lies in their ability to deliver therapeutic agents directly to diseased cells. Utilizing ligand-receptor interactions, these microrobots can bind to target cells and release their payload in a controlled manner. This targeted delivery system not only improves the effectiveness of the drug but also reduces the required dosage, thus mitigating potential side effects. Moreover, smart MXene-based microrobots can facilitate synergistic therapies by co-delivering multiple therapeutic agents. For instance, combining chemotherapy drugs with immunotherapeutic agents could enhance treatment outcomes in cancer therapy. The ability to simultaneously deliver different types of drugs allows for more comprehensive treatment strategies that can tackle tumor heterogeneity. Significant advancements are anticipated in synergistic therapies, particularly in chemo-photothermal, chemodynamic, and photothermal/photodynamic therapies. These strategies leverage multiple therapeutic modalities to enhance cancer treatment outcomes. Despite their outstanding potential, several challenges remain in the development of MXene-based microrobots namely matters pertaining to scalability, stability in biological environments, and associated regulatory hurdles which ought to be addressed. Future research should focus on optimizing the design and functionality of these microrobots, including enhancing their navigation capabilities and ensuring their safety and effectiveness in vivo. By presenting the innovative capabilities of MXene-based microrobots, this perspective aims to inspire additional explorations in the field of advanced targeted drug delivery systems and synergistic therapies, ultimately contributing to the future of personalized medicine and oncology.
Scrutnet: a Deep Ensemble Network for Detecting Fake News in Online Text
(Springer Wien, 2025) Verma, Aryan; Priyanka, P.; Khan, Tayyab; Singh, Karan; Yesufu, Lawal . O.; Ariffin, Mazeyanti Mohd; Ahmadian, Ali
The expeditious propagation of fake news through online social media platforms has cropped up as a captious challenge, undermining the credibility of information sources and affecting public trust. Accurate detection of fake news is imperative to maintain the integrity of online content but is constrained by availability of data. This research aims to detect fake news from online articles by proposing a novel deep learning ensemble network capable of effectively discerning between genuine and fabricated news articles using limited data. We introduce ScrutNet, which leverages the synergistic capabilities of a bidirectional long short-term memory network and a convolutional neural network, which have been meticulously designed and fine-tuned for the task by us. This comprehensive ensemble classifier captures both sequential dependencies and local patterns within the textual data without requiring very large datasets like transformer based models. Through rigorous experimentation, we optimise the individual model parameters and ensemble strategy. The experimental results showcase the remarkable efficacy of ScrutNet in the detection of fake news, with an outstanding precision of 99.56%, 99.43% specificity, and an F1 score of 99.49% achieved on the partition test of the data set. Comparative analysis against state-of-the-art baselines demonstrates the superior performance of ScrutNet, establishing its prominence as a generalised and dependable fake news detection mechanism.
Examining Men's Attitudes Toward Family Planning in Istanbul, Turkey
(Bmc, 2025) Baglan, Derya; Esencan, Tugba Yilmaz
Background Family planning (FP) is a vital component of reproductive health and gender equality, particularly in developing countries. Despite the critical role of men in FP decision-making, their involvement remains limited due to sociocultural factors. This study aims to examine men's attitudes toward FP in Turkey and highlight the need for more inclusive FP strategies. Methods A descriptive study was conducted with 400 male participants residing in Istanbul, using the Family Planning Attitude Scale (FPAS), a validated and standardized questionnaire. Stratified sampling was employed to ensure diverse representation of educational backgrounds and sociodemographic factors. The statistical analyses employed descriptive statistics, an independent sample t-test, a one-way ANOVA, and a Pearson correlation analysis. Results The mean total score of the Family Planning Attitude Scale was found to be 74.5 +/- 30.4, with the mean of the sub-dimensions "attitude towards society" being 31.8 +/- 14.3, "attitude towards methods" being 24.8 +/- 11.2, and "attitude towards pregnancy" being 17.9 +/- 8.0. The total scale score and sub-dimension scores of the participants were found to be at a relatively low level. Significant differences were observed in participants' attitudes towards family planning according to educational level, spouses' educational status, age at early marriage, and having children (p < 0.05). The results indicated that individuals who did not utilize contraceptive methods exhibited more negative attitudes than those who did (M = 84.0 vs. M = 71.1). The criteria that men considered when selecting a family planning method were found to significantly influence their attitudes toward pregnancy (F = 7.02; p = 0.001). Conclusions The findings underscore the necessity of increasing men's FP knowledge and access to contraceptive methods. Targeted interventions should focus on improving men's understanding of FP methods to foster shared decision-making between spouses. Trial registration Clinical trial number: not applicable. The data that support the findings of this study are openly available in the National Thesis Center at tez.yok.gov.tr/UlusalTezMerkezi/tezSorguSonucYeni.jsp.
Which Screening Tool Performs Best in Identifying Malnutrition Risk Among Hospitalized Older Adults With Cardiovascular Disease? a Diagnostic Accuracy Study Comparing Six Different Screening Tools With Glim Criteria
(Springer, 2025) Selcuk, Kevser Tari; Arslan, Sedat; Aydin, Ayca; Durmaz, Duygu
Purpose This study aimed to compare the performance of six different screening tools with the GLIM criteria in identifying malnutrition risk among older adults with cardiovascular diseases. Methods In this diagnostic accuracy study, data from 669 patients aged 65 and older, hospitalized at Band & imath;rma Training and Research Hospital diagnosed with cardiovascular disease, were evaluated. The data were obtained using a questionnaire that included a Demographic Information Form, Global Leadership Initiative on Malnutrition (GLIM) Criteria, Malnutrition Screening Tool (MST), Malnutrition Universal Screening Tool (MUST), Short Nutritional Assessment Questionnaire (SNAQ), Mini Nutritional Assessment-Short Form (MNA-SF), Nutritional Risk Screening-2002 (NRS-2002), and Graz Malnutrition Screening (GMS) tool. GLIM criteria were used as gold standard and six screening tools were used as index tests. Receiver Operating Characteristic (ROC) curve analysis was conducted to calculate the Area Under the Curve (AUC), and the sensitivity, specificity, accuracy, and Cohen's Kappa (kappa) coefficient of the index tests were assessed. Results The mean age of the patients was 75.5 +/- 7.7 years, 55.2% were female. According to the GLIM criteria, the prevalence of malnutrition was calculated as 22.0%. The AUC calculated by ROC indicated that MST (AUC: 0.905) had excellent predictive value, while MUST (AUC: 0.874), SNAQ (AUC: 0.851), MNA-SF (AUC: 0.842), and GMS (AUC: 0.820) demonstrated good predictive value. Among the screening tools, GMS had the highest sensitivity (92.5%), whereas MNA-SF exhibited the highest specificity (91.6%). MNA-SF also demonstrated the highest agreement with the GLIM criteria (Cohen's kappa: 66.8) and the highest accuracy (88.3%). Conclusion This study found that the MNA-SF tool outperformed other comprehensive screening tools when evaluating malnutrition risk in light of the GLIM criteria.
Monomer Release, Cytotoxicity, and Surface Roughness of Temporary Fixed Prosthetic Materials Produced by Digital and Conventional Methods
(Springer, 2025) Sahin, Zeynep; Ozkan Vardar, Deniz; Erdogmus, Ekin; Calamak, Semih; Gumusel, Belma Kocer
This study compared surface roughness, monomer release, and, cytotoxicity of temporary fixed prosthetic materials manufactured using the conventional, CAD/CAM milling and 3D printing methods. Disc-shaped samples (2 mm height, 5 mm diameter) were prepared from four materials [polyethyl methacrylate/polymethyl methacrylate (Dentalon Plus-DP), bis-acrylic composite resin (Protemp 4-PT), polymethyl methacrylate CAD/CAM disc (On Dent), and methacrylate-based resin (QuraCROWN Temp)]. Surface roughness was measured with a profilometer; scanning electron microscopy (SEM) was used for surface characterization. Following 24, 72, and 120 h of artificial saliva incubation for the samples, the obtained extracts were evaluated for cytotoxicity by performing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test in the mouse fibroblast cell. Monomer release from the test samples was analyzed by High-Performance Liquid Chromatography. Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy (ATR-FTIR) was performed to evaluate the chemical composition of artificial saliva extracts. Cell viability was assessed by one-way ANOVA, and surface roughness by Kruskal-Wallis and Mann-Whitney U tests. No monomer was detected in artificial saliva for any materials. The FTIR spectroscopy of the extracts did not show any peaks corresponding to these monomer or polymer structures, indicating that no residual monomer or polymer was released into the artificial saliva after exposure to artificial saliva. 3D-printed materials were significantly more cytotoxic than the other three test materials at all time points and dilutions (p < 0.05). The highest cell viability rates were detected in CAD/CAM milling (99.43 +/- 3.79) at 24 h and PT materials (100.47 +/- 5.31) at 72 h for 1:8 dilution. At 1:4 dilution, except for the DP-3D printing test groups, the other groups show similar cell viability rates with the control group (p > 0.05). Digitally manufactured materials had lower roughness than conventionally produced ones (p < 0.05). CAD/CAM milling and PT materials were the most biocompatible, while 3D-printed material was found to be cytotoxic. CAD/CAM milling and PT materials may offer safe and effective options for temporary prosthetic restorations. Although DP showed acceptable results, it was less effective than CAD/CAM milling and PT materials. Due to their cytotoxicity, 3D-printed materials require further investigation before clinical use.
Serotypes Distribution and Antibiotic Susceptibility of Streptococcus Pneumoniae Strains: Five-Year Surveillance Results of Post-Pcv
(Bmc, 2025) Atici, Serkan; Guneser, Deniz; Kepenekli, Eda; Soyletir, Guner; Soysal, Ahmet
BackgroundApproximately 100 capsular serotypes of S. pneumonia have been identified according to the composition of their capsular polysaccharides, currently available vaccines do not cover many of these. Pneumococcal vaccination serotype coverage is essential for preventing noninvasive and invasive illnesses as well as asymptomatic carriage. We aimed to determine the serotype distribution and antimicrobial susceptibility pattern of pneumococcal clinical isolates in this study. We also analyzed the serotype coverage rates of PCV13, which is applied in the NIP, and PCV-15 and PCV20, which have been introduced recently.MethodsThis study is a retrospective surveillance of pneumococcal infections including invasive pneumococcal isolates (IPIs) and non-invasive pneumococcal isolates (non-IPIs).ResultsA total of 420 isolates from 356 different patients aged 0-89 years were enrolled in the study. A total of 420 pneumococcal isolates were serotyped and 26 different serotypes were detected. Serotype 19 F was the most prevalent serotype (n = 96, 22.8%), followed by 6 A/B (n = 55, 13.1%), 23 F (n = 49, 11.6%), 3 (n = 22, 5.2%) and 19 A (n = 16, 3.8%).ConclusionsSurveillance studies of pneumococcal diseases are critical to investigating current serotype distributions, antibiotic resistance status, and frequency of IPD cases. Considering the increasing antibiotic resistance rates of S. pneumoniae, it is necessary to provide protective immunization by switching to more comprehensive PCV vaccines rather than treatment.Clinical trial numberNot applicable.
Influence of Semolina Cream Addition on the Bioaccessibility of Polyphenols in Walnut-Filled Pastry (Sobiyet)
(Springer, 2025) Bakir, Sena; Kamiloglu, Senem; Ozdal, Tugba; Capanoglu, Esra
Walnuts are widely consumed around the world, and are often used as a filling for pastries, especially in East Asia. In this study, a popular pastry called "sobiyet" was examined to evaluate the interactions between semolina cream and walnuts. The phenolic profile, antioxidant activity, and in vitro bioaccessibility were analyzed. Samples containing 35% (W35%) and 20% (W20%) walnuts (w/w) were prepared with and without the addition of semolina cream. Total phenolic content (TPC) of undigested samples ranged from 417.6 +/- 73.11 mg GAE 100 g(-1) sample to 726.2 +/- 21.66 mg GAE 100 g(-1) sample. Although samples with added semolina cream showed higher TPC levels, the differences were not statistically significant (p > 0.05). In contrast, total antioxidant activity (TAC) levels, as measured by the DPPH and CUPRAC assays, indicated that the addition of semolina cream significantly decreased antioxidant activity (p < 0.05). A similar trend was observed in the in vitro bioaccessibility of individual phenolic compounds. In most cases, no significant differences were observed between samples with higher walnut content (W35%) regardless of whether they contained semolina cream (p > 0.05). However, samples with lower walnut content (W20%) lost some of the phenolic compounds, TPC and TAC during intestinal digestion phase when semolina cream was added (p < 0.05). Overall, the results highlighted that adjusting the walnut content and semolina cream composition in pastries can improve the bioaccessibility of polyphenols, suggesting potential applications in the development of functional foods with enhanced health benefits.
Synthesis of Copper Oxide Nanoparticles and Their Efficiency in Automotive Radiator Heat Transfer Systems
(Elsevier, 2025) Keyvani, Bahram; Aghayari, Reza; Yosefi, Farideh; Toghraie, Davood; Salahshour, Soheil
Enhancing heat transfer in automotive radiators is a matter of concern in the automotive industry. Accordingly, the role of using oxide nanoparticles in various heat exchangers has been extensively studied. However, fewer studies addressed the role of these nanoparticles in radiators. In the present study, copper oxide nanoparticles were synthesized by recycling the spent batteries as copper-rich sources, which is a rather inexpensive and environmentally friendly method of preventing electronic waste production. Subsequently, a homemade singletube heat exchanger apparatus was designed to perform a series of nanofluid heat transfer experiments using the response surface methodology. The performance of copper oxide nanofluid heat transfer effects was investigated using varying Reynolds numbers in the range of 2000 to 12,000, volume fractions in the range of 0.1 to 0.3 %, and inlet temperature of the nanofluid between 30 and 40 degrees C. The results indicated that the Nusselt number increases with the enhancement of nanoparticle concentration, Reynolds number, and temperature. The optimal Nusselt number of 123.4 was observed at a temperature of 40 degrees C, volume concentration of 0.3 %, and Reynolds number of 12,000. The quadratic model demonstrated the best correlation for the Nusselt number, with mean squared error, root mean squared error, and correlation coefficient values of 3.589, 1.894, and 0.9901, respectively. Under such conditions, a satisfactory fit between the experimental data and the proposed rela- tionship was achieved with deviation in the range of +2.1051 and- 2.8369. The corresponding maximum positive and negative errors were 8.0895 and- 10.6169, respectively. The obtained results confirm that the proposed method is not only cost-effective but is also advantageous from environmental considerations.
A Deep Learning Framework for Solving Fractional Partial Differential Equations
(Iop Publishing Ltd, 2025) Ali, Amina; Senu, Norazak; Ahmadian, Ali; Wahi, Nadihah
This research focuses on the study and solution of fractional partial differential equations (FPDEs), a critical area in mathematical analysis. FPDEs pose significant challenges due to their complexity, often requiring extensive computational resources to solve. Given the scarcity of exact solutions, numerical methods have been a primary approach for tackling FPDEs. However, these methods often yield substantial but limited results. The ongoing quest for more effective solutions has led researchers to explore new methodologies. Recent advancements in deep learning (DL), particularly in deep neural networks (DNNs), offer promising tools for solving FPDEs due to their exceptional function-approximation capabilities, demonstrated in diverse applications such as image classification and natural language processing. This research addresses the challenges of solving FPDEs by proposing a novel deep feedforward neural network (DFNN) framework. The method integrates the Laplace transform for memory-efficient Caputo derivative approximations and demonstrates superior accuracy across various examples. The results highlight the framework's versatility and computational efficiency, establishing it as a powerful tool for solving FPDEs.
Measurement of Inclusive and Differential Cross Sections for W+w- Production in Proton-Proton Collisions at √s=13.6 Tev
(Elsevier, 2025) Hayrapetyan, A.; Tumasyan, A.; Adam, W.; Andrejkovic, J. W.; Bergauer, T.; Chatterjee, S.; Zhokin, A.
Measurements at root s = 13.6 TeV of the opposite-sign W boson pair production cross section in proton-proton collisions are presented. The data used in this study were collected with the CMS detector at the CERN LHC in 2022, and correspond to an integrated luminosity of 34.8 fb(-1). Events are selected by requiring one electron and one muon of opposite charge. A maximum likelihood fit is performed on signal- and background-enriched data categories dfined by the flavor and charge of the leptons, the number of jets, and number of jets originating from b quarks. The overall sensitivity is significantly better than that of previous results with a similar integrated luminosity. The improvement comes from a more rfined control of experimental uncertainties and an improved fit strategy. An inclusive W+W- production cross section of 125.7 +/- 5.6 pb is measured, in agreement with standard model predictions. Cross sections are also reported in a fiducial region close to that of the detector acceptance, both inclusively and differentially, as a function of the jet multiplicity in the event. For the first time in proton-proton collisions, WWevents with zero, one, and at least two jets are studied simultaneously and compared with recent theoretical predictions.
Search for a Standard Model-Like Higgs Boson in the Mass Range Between 70 and 110 Gev in the Diphoton Final State in Proton-Proton Collisions at √s=13 Tev
(Elsevier, 2025) Hayrapetyan, A.; Tumasyan, A.; Adam, W.; Andrejkovic, J. W.; Bergauer, T.; Chatterjee, S.; Zhokin, A.
The results of a search for a standard model-like Higgs boson decaying into two photons in the mass range between 70 and 110 GeV are presented. The analysis uses the data set collected by the CMS experiment in proton-proton collisions at root s = 13 TeV corresponding to integrated luminosities of 36.3 fb(-1), 41.5 fb(-1) and 54.4 fb(-1) during the 2016, 2017, and 2018 LHC running periods, respectively. No significant excess over the background expectation is observed and 95% cofidence level upper limits are set on the product of the cross section and branching fraction for decays of an additional Higgs boson into two photons. The maximum deviation with respect to the background is seen for a mass hypothesis of 95.4 GeV with a local (global) significance of 2.9 (1.3) standard deviations. The observed upper limit ranges from 15 to 73 fb.
Single-Phase Multilevel Inverter With a Coupled Inductor
(IEEE-Inst Electrical Electronics Engineers inc, 2025) Alradhawi, Noor Jaafar Jawad; Koc, Sirin; Ghazy, Khaled Heshamt Barakat Mohamed; Khiavi, Abdolhamid Moallemi
Multilevel inverters have become indispensable components in various power electronic applications, particularly in medium-and high-voltage scenarios. This paper introduces a novel single-phase seventeen-level inverter design that utilizes three DC sources and a coupled inductor, resulting in a reduced size and cost. The incorporation of coupled inductors empowers multilevel inverters to enhance performance, yielding high-quality output voltages while minimizing current stress on power devices. A topology-specific level shifted pulse-width modulation (LS-PWM) technique is presented and thoroughly discussed. The proposed topology is simulated and a hardware prototype was constructed to verify the performance of the proposed seventeen-level topology. The outcomes indicate that the implemented topology successfully attains the anticipated performance. Furthermore, a comparative analysis with other existing topologies has been conducted, unequivocally confirming the superior performance, efficiency, and cost of the proposed topology, setting it apart as an outstanding solution in the field of multilevel inverters.

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