Pınar, Lamia

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Pınar, Lamia
Lamia Pınar
Pinar, Lamia
Lamia, Pınar
PINAR Lamia
Lamia Pinar
L., Pınar
Pinar L.
Pinar Lamia
PiNAR Lamia
Pinar, L.
Pınar L.
Pınar, L.
Pınar Lamia
Lamia PiNAR
Lamia PINAR
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Prof.Dr.
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lamia.pinar@okan.edu.tr
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Scholarly Output

3

Articles

2

Citation Count

2

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0

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2021 - 20233
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Now showing 1 - 3 of 3
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    Article
    Citation Count: 0
    Comparison of interleukin-6, oxidant and antioxidant levels in the kidneys of the trained and untrained rats following exhaustive exercise
    (Wageningen Academic Publishers, 2023) Ersever, E. M.; Aral, A.; Goktas, T.; Pinar, L.; Fizyoloji / Physiology; Fizyoloji / Physiology
    In this study, the cytokine response (interleukin-6; IL-6), free oxygen radicals which are claimed to be responsible for the damage in the kidney tissue of exercise-trained rats and untrained-rats, and antioxidant levels were investigated after being forced to an exhausting run. Forty male Wistar albino rats were assigned to the following groups: sedentary controls (C); untrained animals that acutely completed the exhaustive exercise and were sacrificed immediately after exhaustion (UT-i) or 1 day after exhaustion (UT-1); and long-term trained animals that completed the exhaustive exercise and were sacrificed immediately after exhaustion (T-i) or 1 day after exhaustion (T-1). In UT-i and 1 day after exhaustion (T-1) groups, total oxidant status levels were increased compared to controls (P<0.05). IL-6, which is reported to have an anti-inflammatory effect in exercise, did not increase in untrained group immediately, but started to increase 1 day after exhaustion compared to controls. IL-6 levels were significantly increased in the T-i and T-1 groups compared to the control and UT-i groups (P<0.05). The level of total antioxidant status did not show a significant increase in the UT-i group but started to rise after exhaustion the T-1 group. IL-6 levels were significantly increased in the T-i and T-1 groups compared to the control, UT-i, and UT-1 groups (P<0.05). As a result, while oxidant stress and antioxidant mechanism increased immediately in the trained group, IL-6 increased significantly immediately and 1 day later. In the untrained group, however, an increase was observed in oxidant stress, antioxidant mechanism, and IL-6 levels after 1 day.
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    Conference Object
    Citation Count: 0
    Right and Left-Hand Reaction Times to Regular and Irregular Auditory Stimuli in the Sympathetic Phase of Ultradian Rhythm in Right-handed Young People
    (Wiley, 2023) Karaoglu, Isinsu; Pinar, Lamia; Duzlu, Mehmet; Kiziltan, Erhan; Fizyoloji / Physiology
    [No Abstract Available]
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    Article
    Citation Count: 2
    Paraoxonase and oxidative stress changes in left and right ventricles of exhaustively exercised rats
    (Canadian Science Publishing, 2021) Sarikaya, Badegul; Runa, Metin; Dayanir, Duygu; Gunduztepe, Yasemin; Pinar, Lamia; Fizyoloji / Physiology; Fizyoloji / Physiology
    Exhaustive exercise can cause subclinical inflammation to the heart, as it is an oxidative tissue that works continuously. The effect of exhaustive exercise on left and right ventricles (LVs, RVs) may be different. It is claimed that paraoxonase-1 (PON1), an antioxidant enzyme, has a cardioprotective effect on oxidative stress. Rats were separated as non-exercised controls (Con), those euthanized immediately after (E-0) and 24 h after exhaustive exercise (E-24). Cardiac troponin-I (cTnI), total antioxidant status (TAS), total oxidant status (TOS), PON1 activities, and histological findings in LV and RV of the exhausted rats were evaluated. TAS and PON1 levels were lower in LVs compared with RVs of all groups. TOS levels were high in LVs compared with RVs of all groups. In LVs, TAS levels decreased significantly in the E-0 group while PON1 activity decreased in E-0 and E-24 groups compared with controls. In LVs, TOS levels decreased significantly in E-0 and E-24 groups, but in RVs a decrease was seen only in the E-0 group. cTnI levels increased significantly in the E-0 group and decreased to control levels in the E-24 group. Considering the histological and biochemical findings, exhaustive exercise affected the heart to the maximum during and just after exhaustion, and LV was influenced more than RV.