Protective effect of melatonin on the rat lung following exposure to 900-MHz electromagnetic field: a stereological and histopathological study

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dc.authorscopusid56521486700
dc.authorscopusid55898919900
dc.authorscopusid57223211684
dc.authorscopusid15063935100
dc.contributor.authorYahyazadeh,A.
dc.contributor.authorKivrak,E.G.
dc.contributor.authorKoç,G.E.
dc.contributor.authorAltunkaynak,B.Z.
dc.date.accessioned2024-05-25T12:34:09Z
dc.date.available2024-05-25T12:34:09Z
dc.date.issued2021
dc.departmentOkan Universityen_US
dc.department-tempYahyazadeh A., Department of Histology and Embryology, Faculty of Medicine, Karabuk University, Karabuk, Turkey; Kivrak E.G., Department of Histology and Embryology, Faculty of Medicine, Adıyaman University, Adiyaman, Turkey; Koç G.E., Department of Histology and Embryology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey; Altunkaynak B.Z., Department of Histology and Embryology, Faculty of Medicine, Okan University, Istanbul, Turkeyen_US
dc.description.abstractLong-term use of cell phone emitting electromagnetic field (EMF) has increased concerns regarding histopathological change in vital organs. Our present study was aimed to investigate the effect of 900 megahertz (MHz) EMF on the rat lungs, as well as the possible efficacy of melatonin (MEL) on lung tissues. Fifteen female Wistar albino rats were randomly selected and assigned into five groups as follow: control (CONT), SHAM, EMF, melatonin (MEL) and EMF+MEL group. Subsequently, female rats were then mated, and pregnant rats underwent the experimental application for 21 days. After parturition, 6 pups (2 pups from each mother) were randomly chosen and maintained for 4 weeks. At the end of the 4th week, the lung tissues of all groups were used for the stereological analysis and histopathological examination. We found that the mean volumes of the alveoli, bronchioles and blood vessels were significantly lower in the EMF group compared to the control group (p<0.05). In the EMF+MEL group, the mean volumes of the alveoli, bronchioles and blood vessels were significantly increased compared to the EMF group. Our histopathological results showed marked change in the lung tissues. We speculated that exposure to EMF caused the damage to the rat lung tissues, and that MEL administration alleviated 900 MHz EMF-induced complications. © 2021 Ondokuz Mayis Universitesi. All rights reserved.en_US
dc.description.sponsorshipOndokuz Mayis Üniversitesi, (PYO.TIP.1904.11.021)en_US
dc.identifier.citation4
dc.identifier.doi10.52142/omujecm.38.2.1
dc.identifier.endpage60en_US
dc.identifier.issn1309-4483
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85105247320
dc.identifier.scopusqualityQ4
dc.identifier.startpage55en_US
dc.identifier.urihttps://doi.org/10.52142/omujecm.38.2.1
dc.identifier.urihttps://hdl.handle.net/20.500.14517/2549
dc.identifier.volume38en_US
dc.language.isoen
dc.publisherOndokuz Mayis Universitesien_US
dc.relation.ispartofJournal of Experimental and Clinical Medicine (Turkey)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectElectromagnetic fielden_US
dc.subjectLungen_US
dc.subjectMelatoninen_US
dc.subjectRaten_US
dc.subjectStereologyen_US
dc.titleProtective effect of melatonin on the rat lung following exposure to 900-MHz electromagnetic field: a stereological and histopathological studyen_US
dc.typeArticleen_US
dspace.entity.typePublication

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