D vitamini eksikliğinin, vücut yağ yüzdesi, beden kitle indeksi ve bazı kan değerleri üzerine etkisi
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2018
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Bu çalışma D vitamin eksikliği (< 30 ng/ml) tanısı konulmuş 18-60 yaş arası 52 kadın, 50 erkek toplam 102 birey üzerinde, serum D vitamini eksikliğinin beden kitle indeksi, vücut yağ yüzdesi ve bazı kan değerleri üzerine etkisini inceleme amacıyla yapılmıştır. Bireyler D vitamin eksiklik gruplarına gore 10 ng/ml' nin altı şiddetli eksiklik grubu, 10-20 ng/ml arası orta düzey eksiklik grubu, 20-30 ng/ml arası hafif eksiklik grubu olarak, üç gruba ayrılarak değerlendirilmiştir. Bu çalışmada D vitamini eksiklik düzeylerine göre BKI ölçümleri arasında istatistiksel olarak anlamlı farklılık bulunmamıştır (p>0.05). Fakat D vitamini düzeyine göre yağ oranları arasında istatistiksel olarak anlamlı fark bulunmuştur (p<0.01). D vitamini düzeyi 10'un altındaki grubun yağ oranı D vitamini düzeyi 10-20 ng/ ml arası olan gruptan ve 20-30 ng/ml arası olan gruptan anlamlı şekilde yüksektir. Bu çalışmada D vitamini eksikliğinin şiddetine göre açlık kan şekeri, HOMA-IR, HbA1C, ALT, AST değerleri arasında istatistisel olarak anlamlı bir sonuç çıkmamıştır (p>0.05). Çalışmaya katılan bireylerin D vitamini eksiklik düzeylerine göre trigliserit, total kolesterol, HDL ve LDL değerleri arasında istatistiksel olarak anlamlı ilişki olduğu gösterilmiştir (p<0.01). D vitamini düzeyi 10 ng/ml altında olan grubun trigliserit ortalaması D vitamini düzeyi 10-20 ng/ml arasında olan gruptan daha yüksektir. Diğer gruplar arasında istatistiksel olarak anlamlı farklılık bulunmamıştır. D vitamini düzeyi 10-20 ng/ml olan grubun total kolesterol düzeyi, D vitamini düzeyi 10'ng/ml altında olan gruptan anlamlı şekilde yüksektir. Diğer gruplar arasında istatistiksel olarak anlamlı farklılık bulunmamaktadır. D vitamini düzeyi 10 ng/ml altında olan grubun LDL ortalaması D vitamini düzeyi 10-20 ng/ml arasında olan gruptan anlamlı şekilde yüksektir. Diğer gruplar arasında istatistiksel olarak anlamlı farklılık bulunmamaktadır. D vitamini düzeyi 20-30 ng/ml olan grubun HDL ortalaması D vitamini düzeyi 10-20 ng/ml olan gruptan anlamlı şekilde yüksektir. Diğer gruplar arasında istatistiksel olarak anlamlı farklılık bulunmamaktadır. Sonuç olarak D vitamininin eksikliği vücut yağ oranı (%), iç organ yağı, trigliserid ve LDL ters orantılı denilebilir. Tüm bunlar doğrultusunda serum 25(OH) D seviyesi 30 ng/ ml' nin üzerinde tutulması insan sağlığı açısından faydalıdır.
This study was conducted to investigate the effect of serum vitamin D deficiency on body mass index, body fat percentage and some blood values on a total of 102 individuals, 52 female, 50 male, aged 18-60 years, diagnosed with vitamin D deficiency (<30 ng /ml). Individuals were assessed for vitamin D deficiency in three groups, with a severe deficiency group below 10 ng / mL, a moderate deficiency group between 10-20 ng / mL, and a mild deficiency group between 20-30 ng / mL. In this study, there was no statistically significant difference between BMI measurements according to vitamin D deficiency levels (p> 0.05). However, there was a statistically significant difference between the fat ratios according to vitamin D levels (p <0.01). The fat ratio of the group with a vitamin D level below 10 was significantly higher than the group with a vitamin D level of 10-20 ng / ml and the group with a level of 20-30 ng / ml. In this study, there was no statistically significant difference between fasting blood glucose, HOMA-IR, HbA1C, ALT, AST values according to the severity of vitamin D deficiency (p> 0.05). There was a statistically significant correlation between triglyceride, total cholesterol, HDL and LDL levels of the subjects participating in the study according to level of vitamin D deficiency (p <0.01). The mean triglyceride group of the group with a vitamin D level of less than 10 ng / mL is higher than the group with a vitamin D level of 10-20 ng / ml. No statistically significant difference was found between the other groups. The total cholesterol level of the group with a vitamin D level of 10-20 ng / mL was significantly higher than the group with a vitamin D level below 10ng / mL.The mean LDL level of groups with a vitamin D level of less than 10 ng / mL was significantly higher than the group with a vitamin D level of 10-20 ng / mL. There were no statistically significant differences between the other groups. The mean HDL group of patients with a vitamin D level of 20-30 ng / mL was significantly higher than the group with a vitamin D level of 10-20 ng / mL. As a result, vitamin D deficiency can be said to be inversely proportional to body fat percentage (%), internal organ fat, triglyceride and LDL. In line with this, keeping serum 25(OH)D above 30 ng/ml is beneficial for human health.
This study was conducted to investigate the effect of serum vitamin D deficiency on body mass index, body fat percentage and some blood values on a total of 102 individuals, 52 female, 50 male, aged 18-60 years, diagnosed with vitamin D deficiency (<30 ng /ml). Individuals were assessed for vitamin D deficiency in three groups, with a severe deficiency group below 10 ng / mL, a moderate deficiency group between 10-20 ng / mL, and a mild deficiency group between 20-30 ng / mL. In this study, there was no statistically significant difference between BMI measurements according to vitamin D deficiency levels (p> 0.05). However, there was a statistically significant difference between the fat ratios according to vitamin D levels (p <0.01). The fat ratio of the group with a vitamin D level below 10 was significantly higher than the group with a vitamin D level of 10-20 ng / ml and the group with a level of 20-30 ng / ml. In this study, there was no statistically significant difference between fasting blood glucose, HOMA-IR, HbA1C, ALT, AST values according to the severity of vitamin D deficiency (p> 0.05). There was a statistically significant correlation between triglyceride, total cholesterol, HDL and LDL levels of the subjects participating in the study according to level of vitamin D deficiency (p <0.01). The mean triglyceride group of the group with a vitamin D level of less than 10 ng / mL is higher than the group with a vitamin D level of 10-20 ng / ml. No statistically significant difference was found between the other groups. The total cholesterol level of the group with a vitamin D level of 10-20 ng / mL was significantly higher than the group with a vitamin D level below 10ng / mL.The mean LDL level of groups with a vitamin D level of less than 10 ng / mL was significantly higher than the group with a vitamin D level of 10-20 ng / mL. There were no statistically significant differences between the other groups. The mean HDL group of patients with a vitamin D level of 20-30 ng / mL was significantly higher than the group with a vitamin D level of 10-20 ng / mL. As a result, vitamin D deficiency can be said to be inversely proportional to body fat percentage (%), internal organ fat, triglyceride and LDL. In line with this, keeping serum 25(OH)D above 30 ng/ml is beneficial for human health.
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Beslenme ve Diyetetik, Adipoz doku, Kan, Nutrition and Dietetics, Vitamin D, Adipose tissue, Blood, Vitamin D eksikliği, Vitamin D, Vitaminler, Vitamin D deficiency, Vitamins, Vücut kitle indeksi, Body mass index
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