Meme kanserinin obezite ve hiperglisemi ile olan ilişkisi üzerine retrospektif bir araştırma
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2021
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Bu çalışmanın amacı, obezite ile hipergliseminin meme kanseri ile ilişkisini belirlemektir. 2016 Kasım – 2020 Şubat ayları arasında İstanbul'da bir özel hastaneye başvuran, yeni meme kanseri tanısı almış 48 hasta bireylerin (vaka grubu) ile bu gruba yaş bakımından uyumlu 48 meme kanseri öyküsü olmayan sağlıklı bireylerin (kontrol grubu) verileri toplanarak yapılmıştır. Önceki çalışmalardan elde edilen sonuçlara göre vaka grubu ve kontrol grubu için değerlendirme formları oluşturulmuştur. Çalışmadan elde edilen verilerin değerlendirilmesinde Statistical Package for Social Sciences (SPSS) kullanılmıştır. p<0,05 değeri istatistiksel anlamlılık için kullanılmıştır. Çalışma sonuçlarına göre normal Beden Kütle İndeksi (BKİ) aralığında olan bireylerin %28.9'u meme kanserli bireylerden oluşmakta olup, %71.1'i sağlıklı bireylerden oluşmaktadır. Obez olan bireylerin %81.8'i meme kanserli bireylerden oluşurken ve %18.2'si sağlıklı bireylerdir. Bu sonuçlar istatistiksel olarak anlamlıdır (p<0,05). Obezite, meme kanserinin oluşumunu etkileyen bir faktör olarak bulunmuştur. Meme kanserli olan bireylerin kan glikoz değerleri 109,62 olarak bulunmuştur, kontrol grubunun ise 100,96 olarak bulunmuştur. Bu sonuca göre meme kanserli hastaların kan glikoz değerleri, sağlıklı bireylerin kan glikoz değerlerine göre daha yüksektir ve istatistiksel olarak anlamlı fark saptanmıştır (p<0,05). Sonuç olarak, obezite ve hipergliseminin meme kanseri üzerindeki etkisi hakkında daha geniş vaka-kontrol grupları kullanılarak yapılacak olan çalışmalara ihtiyaç vardır.
The aim of this study is to determine the relationship between obesity and hyperglycemia and breast cancer. Data were collected from 48 patients (case group) who were newly diagnosed with breast cancer and who applied to a private hospital in Istanbul between November 2016 and February 2020, and 48 healthy individuals (control group) who were age-matched to this group and did not have a history of breast cancer. According to the results obtained from previous studies, evaluation forms were created for the case group and control group. Statistical Package for Social Sciences (SPSS) was used to evaluate the data obtained from the study. A value of p<0.05 was used for statistical significance. According to the results of the study, 28.9% of individuals with normal BMI are composed of individuals with breast cancer, and 71.1% are healthy individuals. While 81.8% of obese individuals consist of individuals with breast cancer and 18.2% are healthy individuals. These results are statistically significant (p<0.05). Obesity has been found to be a factor affecting the formation of breast cancer. The blood glucose values of individuals with breast cancer were found to be 109.62, while it was found to be 100.96 in the control group. According to this result, the blood glucose values of patients with breast cancer were higher than the blood glucose values of healthy individuals, and a statistically significant difference was found (p<0.05). In conclusion, studies using larger case-control groups are needed on the effect of obesity and hyperglycemia on breast cancer.
The aim of this study is to determine the relationship between obesity and hyperglycemia and breast cancer. Data were collected from 48 patients (case group) who were newly diagnosed with breast cancer and who applied to a private hospital in Istanbul between November 2016 and February 2020, and 48 healthy individuals (control group) who were age-matched to this group and did not have a history of breast cancer. According to the results obtained from previous studies, evaluation forms were created for the case group and control group. Statistical Package for Social Sciences (SPSS) was used to evaluate the data obtained from the study. A value of p<0.05 was used for statistical significance. According to the results of the study, 28.9% of individuals with normal BMI are composed of individuals with breast cancer, and 71.1% are healthy individuals. While 81.8% of obese individuals consist of individuals with breast cancer and 18.2% are healthy individuals. These results are statistically significant (p<0.05). Obesity has been found to be a factor affecting the formation of breast cancer. The blood glucose values of individuals with breast cancer were found to be 109.62, while it was found to be 100.96 in the control group. According to this result, the blood glucose values of patients with breast cancer were higher than the blood glucose values of healthy individuals, and a statistically significant difference was found (p<0.05). In conclusion, studies using larger case-control groups are needed on the effect of obesity and hyperglycemia on breast cancer.
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Beslenme ve Diyetetik, Hiperglisemi, Meme hastalıkları, Meme neoplazmları, Nutrition and Dietetics, Hyperglycemia, Neoplazmlar, Breast diseases, Breast neoplasms, Retrospektif çalışmalar, Neoplasms, Risk faktörleri, Retrospective studies, Risk factors, Vücut kitle indeksi, Body mass index
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64