Antioxidant Activity, Chemical Composition, and Therapeutic Activity of Essential Oils From Certain Lamiaceae Species in Türkiye
dc.authorwosid | Dumlupınar, Berrak/Hir-1759-2022 | |
dc.authorwosid | Seker Karatoprak, Gokce/Aar-4229-2020 | |
dc.contributor.author | Goksu Surucu, Canan | |
dc.contributor.author | Dumlupinar, Berrak | |
dc.contributor.author | Gurbuz, Burcak | |
dc.contributor.author | Seker Karatoprak, Gokce | |
dc.contributor.author | Bahtiyarca, Reyhan | |
dc.contributor.author | Ilgun, Selen | |
dc.date.accessioned | 2025-03-15T20:26:48Z | |
dc.date.available | 2025-03-15T20:26:48Z | |
dc.date.issued | 2025 | |
dc.department | Okan University | en_US |
dc.department-temp | Field Crops Cent Res Inst, Plant Based Food Res Ctr, Sehit Cem Ersever St 11, TR-06170 Yenimahalle, Ankara, Turkiye; [Dumlupinar, Berrak] Istanbul Okan Univ, Fac Hlth Sci, Dept Nutr & Dietet, TR-34959 Tuzla, Istanbul, Turkiye; [Gurbuz, Burcak] Marmara Univ, Fac Pharm, Dept Pharmaceut Microbiol, MU Recep Tayyip Erdogan Social Complex,Basibuyuk R, Basibuyuk, Ankara, Turkiye; [Seker Karatoprak, Gokce] Erciyes Univ, Fac Pharm, Dept Pharmacognosy, TR-38039 Kayseri, Turkiye; [Bahtiyarca, Reyhan] Field Crops Cent Res Inst, Dept Breeding, Sehit Cem Ersever St 11, TR-06170 Yenimahalle, Ankara, Turkiye; [Ilgun, Selen] Erciyes Univ, Fac Pharm, Dept Pharmaceut Bot, TR-38039 Kayseri, Turkiye | en_US |
dc.description.abstract | The study examined the antioxidant, antimicrobial, and potential anticancer properties of lavandin (Lavandula x intermedia 'Grosso'), oregano (Origanum vulgare 'Ulu & gbreve; Bey'), and sage (Salvia officinalis 'Beyhekim') essential oils (EOs). Chemical analysis revealed that oregano is rich in carvacrol (81.23%), cymene (5.51%), and 18-cineole (2.13%). Sage contains notable quantities of alpha-thujone (17.47%), camphor (13.59%), and borneol (12.14%). Lavandin is predominantly composed of linalool (41.10%), linalyl acetate (16.66%), and camphor (10.01%). The antimicrobial tests demonstrated that lavandin EOs exhibited a high inhibition rate of 90.77% at 1000 pg/mL, which subsequently decreased with lower concentrations. The oregano essential oils demonstrated robust antimicrobial activity across all concentrations, with a 10.97% inhibition rate observed even at the lowest concentration. The sage EOs exhibited a rapid decline in antimicrobial activity, reaching 4.97% at the lowest concentration. Both the DPPH and ABTS assays demonstrated that the antioxidant capacity of the essential oils was concentration-dependent. The cytotoxicity values of oregano essential oil were 35.58 at 50 pg/mL, 32.39 at 25 pg/mL, and 30.92 at 12.5 pg/mL. Similar cytotoxicity results were observed for sage and lavandin essential oils. These findings indicate that plant essential oils exert a dose-dependent cytotoxic effect on cell growth, significantly inhibiting cells at high concentrations. The research indicates that essential oils derived from Lamiaceae plants exhibit robust antimicrobial effects against a range of pathogens, suggesting potential applications as alternative therapies for specific microbial infections, comparable to ciprofloxacin at certain concentrations. | en_US |
dc.description.woscitationindex | Emerging Sources Citation Index | |
dc.identifier.citation | 0 | |
dc.identifier.doi | 10.12991/jrespharm.1626231 | |
dc.identifier.endpage | 51 | en_US |
dc.identifier.issn | 2630-6344 | |
dc.identifier.issue | 1 | en_US |
dc.identifier.scopusquality | Q4 | |
dc.identifier.startpage | 30 | en_US |
dc.identifier.uri | https://doi.org/10.12991/jrespharm.1626231 | |
dc.identifier.volume | 29 | en_US |
dc.identifier.wos | WOS:001489648200004 | |
dc.identifier.wosquality | N/A | |
dc.language.iso | en | en_US |
dc.publisher | Marmara Univ, Fac Pharmacy | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Origanum Vulgare Subs. Hirtum | en_US |
dc.subject | Salvia Officinalis L. | en_US |
dc.subject | Lavandula X Intermedia | en_US |
dc.subject | Antioxidant | en_US |
dc.subject | Antimicrobial | en_US |
dc.subject | Cytotoxicity | en_US |
dc.title | Antioxidant Activity, Chemical Composition, and Therapeutic Activity of Essential Oils From Certain Lamiaceae Species in Türkiye | en_US |
dc.type | Article | en_US |