Anaplastic thyroid carcinoma case series

dc.contributor.author Küçüköztaş, Nadire
dc.contributor.author Duman, Tuba Taslamacıoğlu
dc.contributor.author Düzcü, Selma Erdoğan
dc.contributor.author Rahatlı, Samed
dc.contributor.author Üyetürk, Ümmügül
dc.date.accessioned 2024-09-11T07:44:14Z
dc.date.available 2024-09-11T07:44:14Z
dc.date.issued 2024
dc.department Okan University en_US
dc.department-temp BOLU ABANT İZZET BAYSAL ÜNİVERSİTESİ,BOLU ABANT İZZET BAYSAL ÜNİVERSİTESİ,BOLU ABANT İZZET BAYSAL ÜNİVERSİTESİ,BAŞKENT ÜNİVERSİTESİ,İSTANBUL OKAN ÜNİVERSİTESİ en_US
dc.description.abstract Aim: Among the endocrine malignancies, thyroid carcinoma (TC) is the most common. However, anaplastic TC accounts for 1-2% of these cancers. The aim of this study was to evaluate the demographic and pathologic features, treatments, and survival of patients with anaplastic TC. Methods: Anaplastic TC patients who applied to our medical oncology clinics between 01.01.2012 -01.12.2018 were retrospectively evaluated. Results: A total of 8 patients were included in the study. There were 4 female and 4 male patients with a median age of 68 (minimum 61-maximum 83) years. The initial complaint of all patients was a fast-growing swelling in the neck. Six patients had total thyroidectomy. Two patients had anaplastic TC with a differential TC. Six patients were at stage 4C. The most common site of metastasis was the lung (75%). Five patients had received a median of 3 (1-6) cycles of chemotherapy. Radiotherapy was applied to 7 patients. All patients except one died during the follow-up period. The median survival time of the patients was 3 (2-15) months. Conclusion: Anaplastic TC, an aggressive tumor with high metastasic potential, has no effective treatment at present. Effective treatments are needed for this rare and aggressive disease. Developments in the molecular field are promising for the treatment of ATC. en_US
dc.identifier.citationcount 0
dc.identifier.doi 10.54307/NWMJ.2024.86
dc.identifier.endpage 40 en_US
dc.identifier.issn 2757-7724
dc.identifier.issue 1 en_US
dc.identifier.startpage 34 en_US
dc.identifier.trdizinid 1251878
dc.identifier.uri https://doi.org/10.54307/NWMJ.2024.86
dc.identifier.uri https://search.trdizin.gov.tr/en/yayin/detay/1251878/anaplastic-thyroid-carcinoma-case-series
dc.identifier.uri https://hdl.handle.net/20.500.14517/6330
dc.identifier.volume 4 en_US
dc.institutionauthor Üyetürk, Ümmügül
dc.language.iso en
dc.relation.ispartof Northwestern Medical Journal en_US
dc.relation.publicationcategory Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.title Anaplastic thyroid carcinoma case series en_US
dc.type Article en_US

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