The effects of a single high-dose injection of vitamin-D on healing of condylar fractures in osteoporotic rats
| dc.contributor.author | Akif TÜRER | |
| dc.contributor.author | Uğur MERCAN | |
| dc.contributor.author | Osman KELAHMETOĞLU | |
| dc.contributor.author | Yonca Betil KABAK | |
| dc.contributor.author | Deniz Gokce MERAL | |
| dc.date.accessioned | 2024-05-25T12:19:52Z | |
| dc.date.available | 2024-05-25T12:19:52Z | |
| dc.date.issued | 2019 | |
| dc.department | Okan University | en_US |
| dc.department-temp | Bülent Ecevit Üniversitesi, Diş Hekimliği Fakültesi, Ağız Diş Çene Hastalıkları ve Cerrahisi Anabilim Dalı, Zonguldak, Türkiye Okan Üniversitesi, Diş Hekimliği Fakültesi, Ağız Diş Çene Hastalıkları ve Cerrahisi Anabilim Dalı, İstanbul, Türkiye Bezmi Alem Üniversitesi, Tıp Fakültesi, Plastik ve Rekonstrüktif Cerrahi Anabilim Dalı, İstanbul, Türkiye Ondokuz Mayıs Üniversitesi, Veteriner Fakültesi, Patoloji Anabilim Dalı, Samsun, Türkiye Okan Üniversitesi, Diş Hekimliği Fakültesi, Ağız Diş Çene Hastalıkları ve Cerrahisi Anabilim Dalı, İstanbul, Türkiye | en_US |
| dc.description.abstract | Aim: In this study we have tried to show the effects of a singlehigh-dose ınjection of vitamin d on healing of condylar fractures in osteoporotic rats.Materials and method: This study included sixteen femalewistar rats. All rats were overiectomized. Osteoporotic ratswere randomly divided into two groups of eight animals/group. Group D animals received a single high dose of vitamin D (50.000 IU/kg) intraperitoneally and group C (control)animals received saline (0.05 mL) intraperitoneally. All injections were given immediately after condylar fracture. All ratswere euthanized after 28 days, examined histopathologicaland immunohistochemical.Results: Histopathological and immunohistochemical evaluations were done. Histopathological scores between groupD and C were found statistically significant. TGFβ1 and osteopentin levels in group D were found higher than group C.Conclusion: We have determined that a single high-dose injection of vitamin D given immediately after surgery increasedTGFβ and osteopontin levels and enhanced new bone formation at condylar fractures of osteoporotic rats. | en_US |
| dc.identifier.citationcount | 0 | |
| dc.identifier.doi | 10.5505/yeditepe.2019.83792 | |
| dc.identifier.endpage | 76 | en_US |
| dc.identifier.issn | 2458-9586 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.startpage | 70 | en_US |
| dc.identifier.trdizinid | 312179 | |
| dc.identifier.uri | https://doi.org/10.5505/yeditepe.2019.83792 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/tr/yayin/detay/312179/the-effects-of-a-single-high-dose-injection-of-vitamin-d-on-healing-of-condylar-fractures-in-osteoporotic-rats | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14517/1847 | |
| dc.identifier.volume | 15 | en_US |
| dc.institutionauthor | Meral, Deniz Gökçe | |
| dc.language.iso | en | |
| dc.relation.ispartof | 7tepe Klinik | en_US |
| dc.relation.publicationcategory | Diğer | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | [Fen > Diş Hekimliği > Diş Hekimliği] | en_US |
| dc.title | The effects of a single high-dose injection of vitamin-D on healing of condylar fractures in osteoporotic rats | en_US |
| dc.type | Article | en_US |