TR Dizin İndeksli Yayınlar / TR Dizin Indexed Publications Collection
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Article 5th and 6th grade students' perceptions of communication(Pegem Akad Yayincilik Egitim Danismanlik Hizmetleri Tic Ltd Sti, 2020) Sarkin, Dondu Bahar Sahin; Duran, AyseminThis study aims to examine how 5th and 6th grade students perceive the phenomenon of communication. It was designed as a qualitative research and the phenomenological method was used. Totally, 80 students constituted the study group. A two-part "Communication Perception Form" was created by the researchers in order to determine the perceptions of the students regarding the phenomenon of communication. Content analysis technique was used in evaluating the data obtained in this study. Data on the phenomenon of communication were gathered among five categories (nature, emotion, food, existence, tool/mediator). In the visual metaphors of the students, it was seen that they drew telephone and talking people mostly. The metaphors developed by the 5th and 6th graders, which are the first levels of secondary school, can be considered as important indicators for understanding the positive and negative effects of communication on students. In this study, where communication generally evokes speech or correspondence, it can be suggested that students acquire this skill in various fields through programs, since it is seen that students make more in-depth descriptions in visual expression.Article Aberrant socs3 promoter methylation as a noninvasive diagnostic biomarker for locally advanced prostate cancer;(Logos Medical Publishing, 2020) Demircan Tan,B.; Turan,T.; Yucel,B.; Altundag Kara,S.; Salman Yilmaz,S.; Yildirim,A.Objective: The aim of this study was to investigate the promoter methylation status of Rasassociated domain family 1A (RASSF1A), O-6-methylguanine-DNA methyltransferase (MGMT), Phosphatase with tensin homology (PTEN) and Suppressor of cytokine signaling 3 (SOCS3) tumor suppressor genes and evaluate the clinical utility of these genes as noninvasive, bloodbased epigenetic biomarkers for the diagnosis of Prostate Cancer (PCa). Method: A total of 41 consecutive patients and 10 healthy control groups were enrolled in the study. Pyrosequencing was performed to analyze the methylation levels of the promoter regions of the four tumor suppressor genes in patients compared to healthy controls. Results: The promoter methylation levels of RASSF1A, MGMT, PTEN and SOCS3 did not differ between the patient and control groups. However, SOCS3 promoter methylation level was significantly higher for patients having locally advanced PCa compared to those having localized PCa (p<0.05). Conclusion: Our results indicated that SOCS3 could be a useful, noninvasive blood-based epigenetic biomarker for the diagnosis of locally advanced PCa. © Istanbul Medeniyet University Faculty of Medicine.Article Accelerated Alkali-Silica Reaction After a Seven-Year Asr-Dormancy Period(Kare Publishing, 2024) Beglarigale, AhsanollahThe ongoing alkali-silica reaction (ASR) in concrete can be halted by dryness, which is im- portant for repairing ASR-suffered concrete structures. Drying of the concrete establishes an ASR-dormancy period until the end of the dryness. The residual expansion of such concrete after the ingress of water—the end of the dormancy period—is a significant risk, especially for repair works. In this experimental study, the post-dormancy expansion of various mixtures prepared by eight different Portland cement and three different supplementary cementitious materials (SCM) were tested using an accelerated mortar bar test. After accelerated ASR ex- pansions, an ASR-dormancy period was established by keeping the specimens dry for seven years; the residual ASR expansions of the specimens were tested by the same accelerated meth- od. The effect of pre-dormancy reactions on the residual expansions was discussed through two perspectives. The post-dormancy expansion behavior of mixtures without or with insuffi- cient SCM indicated that expansions were primarily driven by the swelling of old gel, whereas in specimens with sufficient SCM, the dominant mechanism was new gel formation, a result of lower pre-dormancy expansions due to the ASR-mitigating effect of SCMs.Article Accuracy of Procalcitonin in the Diagnosis of Bacteremia and Discrimination from Contamination(Istanbul University Press, 2025) Hayirlioglu, N.; Kaya, A.D.; Selale, D.S.; Kurç, M.A.; Varol, G.Objective: In this study, we aimed to evaluate the concordance of blood culture with procalcitonin (PCT) alone and together with C-reactive protein (CRP) in detecting bacteremia and the diagnostic performance of these biomarkers to differentiate contamination from true bacteremia. Materials and Methods: The medical records of 310 patients were analysed retrospectively. Advia Centaur XP immunoassay system and Au analysers were used to determine PCT and CRP levels, respectively. BacT/ Alert 3D60 hemoculture system was used to incubate blood specimens, and VITEK 2 compact was used to identify isolated strains. Results: The accuracy of PCT and CRP in detecting bacteremia were found to be 68.1% and 36.4%, respectively, and combining PCT and CRP had no added value. In analysis of receiver operating characteristic (ROC), the area under the ROC curve (AUROC) values of PCT and CRP were found to be 0.889 and 0.779 in discriminating the culture-negative group from the culture-positive group, and 0.645 and 0.502 in discriminating bacteremia from contamination, respectively. Conclusion: PCT is a reliable marker that can be used to detect bacteremia. However, its discriminative power was low in differentiating true bacteremia from contamination. Therefore, PCT levels alone should not be used to rule out blood culture contamination. © 2025 Elsevier B.V., All rights reserved.Article Acil Serviste Hasta Yakınları Öfke Seviyesi ve Düşünce Özellikleri İlişkisi: Pilot Çalışma(2023) Yaşar, Alişan Burak; Gündoğmuş, İbrahim; Taycan, Serap Erdoğan; Özdel, Kadir; Türkçapar, Mehmet Hakan; Usta, DilaraŞiddete yönelik müdahalelerin planlanması için mevcut çalışma acil servis bekleme salonundaki hasta yakınlarının öfke ve şiddete eğilimleri ile bilişsel çarpıtmaları arasındaki olası bağıntıların belirlenmesine odaklanmaktadır. Kesitsel tipteki mevcut çalışma acil servise başvuran hastaların çalışmaya katılmayı kabul eden 37 yakını ile gerçekleştirilmiştir. Katılımcılara Sosyodemografik veri formu, Sürekli Öfke-Öfke Tarz Ölçeği (SÖÖTÖ), Şiddet Eğilim Ölçeği, Düşünce Özellikleri Ölçeği (DÖÖ), Öznel Düşünceler İnanç Ölçeği (ÖDİÖ) ve Öznel Öfke ve Sıkıntı Ölçeği (ÖÖSÖ) uygulanmıştır. Çalışmaya dâhil edilen katılımcıların yaş ortalaması 31,83±10,35 yıldı ve 21’i (%56,8) kadındı. Düşünce özellikleri ölçeği “-meli, –malı ifade” ile SÖÖTÖ skoru ile arasında olumlu yönde istatiksel olarak anlamı bir korelasyon bulunmuştur (r=0,480, p=0,020). Düşünce özellikleri ölçeği “hep ya da hiç” alt boyutu ile ÖÖSÖ Sıkıntı skoru arasında olumlu yönde istatiksel olarak anlamı bir korelasyon bulunmuştur (r=0,445, p=0,038). Öznel öfke ve sıkıntı ölçeği Sıkıntı ve Öfke skorları arasında pozitif yönlü istatiksel olarak anlamlı bir ilişki saptanmıştır (r=0,830, p<0,001). Öznel düşünceler inanç ölçeği doktor skoru ile hemşire (r=0,694, p<0,001) ve sağlık personeli (r=0,546, p<0,001) skorları arasında ve hemşire ve sağlık personeli skorları (r=0,683, p<0,001) arasında pozitif yönde istatiksel olarak anlamı bir korelasyon bulunmuştur. Çalışmamız acil serviste hasta yakınlarının öfkeleri ile bilişsel çarpıtmalar arasında ilişki olduğunu ortaya koymuştur. Bu bağlamda sonuçlarımızın şiddet uygulayan bireylerin tanınmasında faydalı olacağı düşünülebilir. Bu konuya yönelik daha geniş örneklemli çalışmaların yapılmasının gerektiği açıktır.Article )actors affecting success in intrauterine insemination cycles 2-year single center e[perience(2021) Gizem Berfin ULUUTKU; Rahime Nida BAYIK; İbrahim KALE; Başak ERGİNObjective: The aim of this study is to evaluate the success rates of intrauterine insemination cycles due to ovulation induction with clomiphene citrate and gonadotropins, and to identify factors associated with successful outcomes in women with unexplained infertility and ovulatory dysfunction. Material and Methods: Between June 2017 and October 2019, 223 intrauterine insemination cycle records were scanned retrospectively in 152 infertile couples diagnosed with ovulatory dysfunction or unexplained infertility. Result: A total of 33 positive pregnancy test results were obtained, which had shown a pregnancy success rate of 14.8%. Pregnancy success rate in Gonadotropin IUI (Intrauterine Insemination) cycles was found as 16.6% and pregnancy success rate in CC (Clomiphene Citrate) IUI cycles was found as 9.3%. While it has been detected that smoking has had a negative effect on IUI success rate for the infertile population with ovulatory dysfunction and unexplained infertility (p=0.012); factors such as female age, BMI (Body mass index), infertility span, basal FSH (Follicle Stimulating Hormone), basal LH (Luteinizing Hormone), basal estradiol levels and trigger-day endometrial thickness were found to have no correlation with IUI success rate at all.Review Acute spinal epidural hematoma: A case report and review of the literature(Turkish Assoc Trauma Emergency Surgery, 2020) Akar, Ezgi; Ogrenci, Ahmet; Koban, Orkun; Yilmaz, Mesut; Dalbayrak, SedatSpinal epidural hematoma (SEH) is a rare but a significant cause of spinal cord compression and neurologic deficits. Its etiology is usually unknown and requires emergency intervention. The present study aims to review the clinical significance, treatment strategies and clinical outcomes of traumatic SEH with a rare case presentation. Our patient was a 42-year-old female who presented with back pain and loss of sensation and strength in the legs. The patient did not have any disease and did not use anticoagulant drugs. The patient developed numbness in her legs half an hour after having a traditional back walking massage due to occasional back pain. She was paraplegic and anesthetic when seen in our clinic. Thoracic computed tomography (CT) and magnetic resonance imaging (MRI) revealed posterior epidural hemorrhage at Th3-Th4 levels. In the 12th hour, the hematoma was evacuated by an emergency decompressive hemilaminectomy. At the postoperative 24th hour, the patient had symptomatic improvement, and in the sixth month, the patient was mobilized with support. SEH is a rare condition that should be considered in patients with sudden onset of back pain and extremity weakness. Although the gold standard diagnostic tool is MRI, CT is often sufficient to avoid delayed surgery. Immediate surgical decompression (laminectomy/hemilaminectomy) should be performed in cases diagnosed with SEH with neurological deficits.Article Adaptation of COVID-19 risk perception and COVID-19 prevention guidelines compliance scales to Turkish: a validity and reliability study(2021) Nazlı Kaya; Özlem Karatana; Emre İşçiAim: The aim of this study is to make Turkish adaptation and psychometric analysis of the COVID-19 Risk Perception and COVID-19 Prevention Guideline Compliance scales. Material and Method: The COVID-19 Risk Perception and COVID-19 Prevention Guideline Compliance scales administered to a total of 385 healthcare workers (Emergency medical technician, paramedic, ambulance driver etc.) and 50 healthcare workers were retested two weeks later. The opinions of 10 experts were taken for the content validity of the scale, the confirmatory factor analysis was performed for the construct validity, the Cronbach's alpha reliability coefficient was calculated to determine the internal consistency, and the test-retest reliability was performed and the results were evaluated with Pearson correlation analysis. Results: It can be concluded that an agreement among experts according to the results of the content validity index of the Turkish version of COVID-19 Risk Perception scale was found to be 0.91, the COVID-19 prevention guideline compliance scale was found to be 1. The test-retest reliability correlation of the scales was 0.85. Conclusion: COVID-19 Risk Perception and the COVID-19 prevention guideline compliance scales were suitable for Turkish culture, and they are valid and reliable.Article Adaptation of internal audit system to supervisory system in the provincial directorate of national education and a model proposal(Pegem Akad Yayincilik Egitim Danismanlik Hizmetleri Tic Ltd Sti, 2020) Baris, Ali Erkan; Atanur Baskan, GulsunThe aim of this research is to provide a supervision model for provincial directorates of national education in accordance with contemporary audit approaches. The study is designed as a mixed research method. The participants of the study include 4082 people; 3576 teachers, 452 administrators (10 provincial/district national education directors and assistant directors, 11 branch managers, 431 school principals and assistant principals) and 10 education supervisors working in public schools and institutions in Nevsehir in 2017 and 44 education supervisors working in the ministry of education. Data collection tools were developed by the researcher. The quantitative data were collected by the Adoption and Applicability Scale of the Internal Audit System (AASIAS). Qualitative data were collected through semi-structured interview form. Results of the study showed that the participants adopted the internal audit system to a great extent and found it applicable in provincial directorates of national education. In addition, the opinions of the participants were integrated into the internal audit system and a supervision model was developed for the purpose, structure and process dimensions of provincial directorates of national education.Article The Adaptation Study of The Metacognition, Self-efficacy and Learning Processes Scale into Turkish: Results of Confirmatory Factor Analysis(2016) R. Suat IŞILDAK; M. Sabri KOCAKÜLAH; Mustafa ÇORAMIK; Erdoğan ÖZDEMİR.This study involves the adaptation of a scale into Turkish which is developed by Thomas, Andersonand Nashon (2008) to investigate elements of students’ metacognition, self-efficacy and constructivist sciencelearning processes. In this context linguistic equivalence, validity and reliability analyses were conducted. Thescale was administered to 913 secondary school students aged between 15 and 18 years of age in four cities ofTurkey. Results of the confirmatory factor analyses [2(395, n=913)=1137.10, p<.000; RMSEA=.045;GFI=.92; CFI=.93; NNFI=.92] show that five factorial construct of the original scale was preserved in theTurkish form. Factor loadings differ from 0.50 to 0.70 for items and item-total score correlations ranged from0.39 to 0.65. The Cronbach alpha coefficient for whole scale was also calculated as 0.93.Article Adherence to guideline-directed medical and device Therapy in outpAtients with heart failure with reduced ejection fraction: The ATA study(Turkish Soc Cardiology, 2020) Kocabas, Umut; Kivrak, Tarik; Oztekin, Gulsum Meral Yilmaz; Tanik, Veysel Ozan; Ozdemir, Ibrahim Halil; Kaya, Ersin; Pehlivanoglu, SeckinObjective: Despite recommendations from heart failure guidelines on the use of pharmacologic and device therapy in patients with heart failure with reduced ejection fraction (HFrEF), important inconsistencies in guideline adherence persist in practice. The aim of this study was to assess adherence to guideline-directed medical and device therapy for the treatment of patients with chronic HFrEF (left ventricular ejection fraction <= 40%). Methods: The Adherence to guideline-directed medical and device Therapy in outpAtients with HFrEF (ATA) study is a prospective, multicenter, observational study conducted in 24 centers from January 2019 to June 2019. Results: The study included 1462 outpatients (male: 70.1%, mean age: 67 +/- 11 years, mean LVEF: 30%+/- 6%) with chronic HFrEF. Renin-angiotensin system (RAS) inhibitors, beta-blockers, mineralocorticoid receptor antagonists (MRAs), and ivabradin were used in 78.2%, 90.2%, 55.4%, and 12.1% of patients, respectively. The proportion of patients receiving target doses of medical treatments was 24.6% for RAS inhibitors, 9.9% for beta-blockers, and 10.5% for MRAs. Among patients who met the criteria for implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy (CRT), only 16.9% of patients received an ICD (167 of 983) and 34% (95 of 279) of patients underwent CRT (95 of 279). Conclusion: The ATA study shows that most HFrEF outpatients receive RAS inhibitors and beta-blockers but not MRAs or ivabradin when the medical reasons for nonuse, such as drug intolerance or contraindications, are taken into account. In addition, most eligible patients with HFrEF do not receive target doses of pharmacological treatments or guideline-recommended device therapy.Article Adolesan kadın basketbol oyuncularında anaerobık yorgunluğun proprıosepsıyon üzerıne etkısı(Turkey AsSoc Physiotherapists, 2025) Kilic, Sefa; Alpay, Kubra; Atici, Emine; Soyal, Mehmet; Inal-Gultekin, GuldalProproseptif duyudaki eksiklikler yaralanma riskini artırmakta ve sporcunun performansını olumsuz yönde etkilemektedir. Kadın basketbol oyuncularında anaerobik yorgunluğun ve toparlanma sürecinin propriosepsiyon üzerine etkisi üzerinde sınırlı sayıda çalışma bulunmaktadır. Bu amaçla adolesan kadın basketbol oyuncularında anaerobik yorgunluğun alt ekstremite propriosepsiyonu üzerine etkisini değerlendirilmiştir. Çalışmaya 12–16 yaş aralığında 30 lisanslı kadın basketbol oyuncusu dahil edildi. Katılımcıların demografik bilgilerine takiben, istirahat, yorgunluk ve toparlanma olmak üzere üç durumda kalp atım sayıları, 30° ve 60° aktif ve pasif diz eklemi pozisyon hissi ölçümleri yapıldı. Diz eklemi pozisyon hissi ölçümleri için dominant bacakları değerlendirmeye alındı. Anaerobik yorgunluk için bisiklet ergometresinde Wingate anaerobik test protokolü uygulandı ve hemen sonrasındaki yorgunluk durumu verileri alındı. Toparlanma sonrası verilerin alınması için katılımcılar 10 dakika istirahate alındılar. Katılımcıların elde edilen yorgunluk nabızları ortalama 171,6±4,2 atım/dakika olarak tespit edildi ve karvonen formülüne göre hesaplanan iş yoğunluğu %72,7±2,9 olarak belirlendi. Anaerobik yorgunluk sonrası 30° ve 60° diz fleksiyonu aktif eklem pozisyon hissinde istirahat değelerine göre anlamlı azalma saptandı (p>0,017). Yorgunluk sonrası 10 dakikalık toparlanma ile 30° ve 60° diz fleksiyonu aktif eklem pozisyon hissinde tekrar istirahat seviyelerine dönüş olduğu belirlendi. Diz fleksiyonu 30° ve 60° pasif eklem pozisyon hissinde anaerobik yorgunluk sonrası anlamlı farklılık tespit edilmedi. Sonuç olarak, adolesan kadın basketbolcularında anaerobik yorgunluğun diz propripsepsiyonunu azalttağı saptanmış ve çalışmanın literatürdeki benzer bulgularla örtüştüğü görülmüştür. Bunula birlikte, 10 dakika kadar kısa bir toparlanma süresi ile propriyoseptif duyarlılığın başlangıç seviyelerine geri döndüğü görülmüştür.Article AKUT MİYELOİD LÖSEMİDE SWITCH/SUKROZ FERMENTE EDILEMEZ KROMATİN YENİDEN ŞEKİLLENDİRME KOMPLEKSİNİN GENOMİK GÖRÜNÜMÜ(2024) Ozkan, Didem Torun; Akın, Dilara FatmaSWI/SNF kromatin yeniden modelleme kompleksi, hematopoietik kök hücrelerde hücre bakımı ve farklılaşma gibi süreçler için gerekli olan gen ekspresyonunun düzenlenmesinde görev alır. Hematolojik süreçlerin homeostazında yer alan SWI/SNF kompleksi alt birimlerindeki değişiklikler hematolojik malignitelerin başlamasına veya ilerlemesine katkıda bulunmaktadır, ancak bu fenotipin arkasındaki mekanizmalar tam olarak açıklanmamıştır. Çalışmada, SWI/SNF kompleksini oluşturan genlerde mutasyonların ve ekspresyon profilinin biyoinformatik araçları kullanılarak kapsamlı belirlenmesi amaçlanmıştır. AML kohortuna (n:872) ait genom dizileri ve ifade profillerine biyoinformatik araçlar aracılığı ile elde edilmiş ve analiz edilmiştir. Kompleksin alt ünitelerini kodlayan 9 gende ARID1A, ARID1B, SMARCA2, SMARCA4, SMARCE1, SMARCB1, DPF2, PMBR1 ve BCL7A belirlenen mutasyonların AML patogenezinde onkojenik/patojenik etkilerinin tahmini PolyPhen-2, SIFT ve Mutation Assessor araçları kullanılmıştır. Mutasyona uğrayan proteinlerinin fonksiyenel etkilerini anlamak için STRING aracı ile analiz gerçekleştirilmiştir. Mutasyon profili değil aynı zamanda mutasyon varlığının gen ifadesi ve sağ kalım üzerine etkileride değerlendirilmiştir. 9 gende 9 yanlış anlam, 6 çerçeve kayması mutasyon, 1 splize bölge ve 1 füzyon mutasyonu olmak üzere toplam 17 genetik anormallik belirlenmiştir. AML kohortunda ARID1A, ARID1B, SMARCA2 ve PMBR1 ekspresyon seviyelerin hasta grubunda sağlıklı gruba yüksek ve istatistiksel olarak anlamlıdır (p<0.01). Düşük ve yüksek gen ekspresyon profillerine göre yapılan sağ kalım analizi sonuçlarımızda bir farklılık görülmemiştir. STRING analizinde, hedef genlerimizin, hücre döngüsü kontrolünde görev alan PHF10 ile fonksiyonel ilişkileri bulunduğu belirlenmiştir. Sonuç olarak, sonuçlarımız, ARID1A, ARID1B, SMARCA2, SMARCA4 ve PBRM1’de tespit ettiğimiz mutasyonlarının, SWI/SNF kromatin yeniden modelleme komplekslerinin fonksiyonunu bozarak AML patogenezi sırasında farklı kromatin ortamlarını içeren farklı hücresel yolları indükleyebileceği/inaktive edebileceğini düşündürmektedir.Review ALMANYA VE TÜRKİYE’DE SAĞLIKTA KALİTE İNDİKATÖRLERİ VE BEKLENMEYEN OLAY YAKLAŞIMLARI ÜZERİNE BİR DERLEME(2024) Özmen, Oğuzhan; İper, Hatice Semrin TimlioğluHasta güvenliğini sağlamak amacıyla kalite çalışmalarının değerlendirilmesi kalitenin ölçülmesi ile mümkün olmaktadır. Kalitenin ölçülmesi için “Kalite İndikatörleri” kullanılmaktadır. Kalite indikatörlerinin belirlenmesi ve gerçekçi ölçümlerin yapılabilmesi için ise bu indikatörler temelinde ortaya çıkmış olan beklenmeyen olayların tespit edilmesi ve bildirilmesi neticesinde kalitenin ölçülmesinin mümkün hale gelmesi sağlık sistemlerinin geliştirilmesi için çok değerli sonuçlar ortaya koymaktadır. Bu çalışmada “Sağlıkta Kalite Uygulamaları” kalite indikatörleri ve beklenmeyen olaylar odağında, Avrupa Birliği üyesi ve gelişmiş ülke konumundaki Almanya ile Avrupa Birliği yolunda ilerleyen ve gelişmekte olan bir ülke konumundaki Türkiyekarşılaştırılmıştır. Çalışmada Sağlıkta Kalite Uygulamalarının karşılaştırmalı değerlendirme neticesinde tanınması, iki ülkenin kalite indikatörleri ve beklenmeyen olaylara yaklaşımlarının olumlu ve olumsuz yönlerinin tartışılması ve uygulama güncellemeleri için alternatif olabilecek yöntemler önerilmesi amaçlanmıştır. Sonuç olarak; Almanya’da Kalite Programı “Geniş Katılımlı Veri Temelli Kalite Programı” olarak tanımlanabilir. Almanya’da Beklenmeyen Olay Bildirimleri için hastaneler özendirilmekte, kaliteye yöneltilmekte, sağlık hizmetinde kalite rekabeti oluşturulmaktadır. Ancak ödemeler ve finansal kaygılar göz önüne alındığında bu rekabetin sadece kalite göstergelerinin halka ulaştırılmasıyla sağlanamayacağı hissedilmektedir. Türkiye’de kalite indikatörlerinin kullanılmasını sağlayacak sistemde çok iyi bir seviye yakalanmış olmasına rağmen beklenmeyen olay bildirimi, kalite indikatörlerinin işletilmesi ve sonuçların paylaşılması hususlarında aksaklıklar hissedilmektedir.Article Ambiguus Genitalya ve Böbrek Agenezisi ile Birlikte Görülen Heterofagusun en Nadir Formu Olan İskiofagus Vakası(2020) Çalışkan, Eray; Haqverdiyev, Emin; Akar, Bertan; Gümüştaş, Gokhan; Aslancan, ReyhanParazit iki kiz parsiyel olarak rezorbe olmuş ve normal fetus üzerinde yerleşmiş inkomplet fetüsü tariflemek için kullanılan bir terimdir. İskiofagus normal fetuse ileumdan bağlanmış parazitik fetüsü ifade edip parazit ikiz vakalarının en nadir görülen formudur. Bu vakada on üç haftalık fetus birinci trimester ultrasonografik incelemesinde iskiofagus, ambiguus genitalya ve böbrek agenezisi tanısı almıştır. Ailenin kararı sonucu terminasyon uygulanmıştır. Parazitik ikiz vakaları eşlik edebilecek multisistemik anomaliler açısından dikkatli incelenmelidir. Aileyi fetüsün durumunun yaşamla bağdaşırlığı açısından bilgilendirmek gereksiz terminasyonları önlemek açısından önemlidir.Article Analysis and Comparison of Electric Scooter Crashes: A Review of Crash Characteristics and Health Outcomes in Türkiye(2024) Dündar, Selim; Okudan, BegümMicromobility, including shared e-scooters, has become a convenient mode of transportation for short-distance trips globally. Türkiye introduced shared e-scooters in 2019, quickly expanding their presence. This study analyses and identifies the crash characteristics and health outcomes of e-scooter crashes in Türkiye. It also seeks to provide recommendations for enhancing safety. This review focused on e-scooter crashes in Türkiye, a country with a population of 85,279,553. Our narrative analysis examined eight studies and eight media reports on e-scooter incidents in Türkiye, evaluating patient demographics, crash characteristics (user type, fall/collision, speed, time, location), injury types, interventions, hospitalizations, and modifiable risk factors like helmet use and alcohol consumption. Accidental involvement was slightly higher in men than in women. The rate of helmet usage is quite low. Upper extremity injuries are the most common type, followed by lower extremity injuries. Fatalities have occurred, underscoring public health concerns. E-scooter crashes often involve collisions with pedestrians and vehicles, highlighting the need for adherence to traffic rules and safe riding practices. E-scooters are a practical transportation solution but pose safety risks. Protective measures such as helmet and other protective equipment use, compliance with traffic rules, and public awareness campaigns are crucial to mitigate these risks. We conclude that e-scooter safety regulations in Türkiye should be enhanced to protect riders and pedestrians and promote a safer micromobility ecosystem.Article Analysis of a Prefabricated Vertical Drain (PVD) Soil Improvement Project(Turkish Chamber Civil Engineers, 2022) Mert, Ahmet Can; Onalp, Akin; Arel, ErsinA settlement analysis has been carried out for several sectors of a rail station yard improved with prefabricated vertical drains (PVD) in Istanbul, that exhibited prolonged consolidation beyond the predicted values in certain sectors of the treated zone. Final settlement and End of Primary (EOP) settlement times have been estimated theoretically as well as using the Asaoka graphical procedure. The compliance of settlement-time curves with in-situ measurements and Asaoka solution has been investigated. A geotechnical model was developed for finite element and three-dimensional consolidation analyses. The settlement curves obtained by varying horizontal-vertical permeability coefficient ratio (k(h)/k(v)) and in-situ measurements have been compared, and k(h)/k(v) values corresponding to 90% degree of consolidation has been computed for all sectors. The effect of drain spacing (S-drain) as well as drain length (L-drain) on the rate of consolidation have been evaluated for each sector, keeping the specified ratios constant. The times corresponding to 95% degree of consolidation (t(95)) have been calculated using the theoretical solution and compared to in-situ measurements. Calculated t(95)'s has also been compared to their estimated values by varying the spacing (S-drain) and the length (L-drain). Additionally, the required intervals of S-drain and L-drain have been obtained corresponding to the calculated t(95) times. The analyses suggest that the main reason for prolonged consolidation was the horizontal to vertical permeability coefficient ratio. According to the analysis results, PVD implementation was not efficient in clays having k(h)/k(v) of approximately unity. The main conclusion of this study was to discover the necessity for optimizing the variables in any such project. The efficacy of the works can be significantly enhanced if simultaneous evaluation of the parameters S-drain and L-drain and the permeability ratio k(h)/k(v) is carried out prior to field work. Otherwise, "accidents" may emerge as found out in this project.Article Analysis of complications following posterior vertebral column resection for the treatment of severe angular kyphosis greater than 100(2017) Balioğlu, Mehmet Bülent; Albayrak, Akif; Atıcı, Yunus; Kargın, Deniz; Mert, Muhammed; Kaygusuz, Mehmet AkifObjective: The aim of this study was to evaluate the complications, efŞcacy and safety of posteriorvertebral column resection (PVCR) in severe angular kyphosis (SAK) greater than 100.Methods: The medical records of 17 patients (mean age 17.9 (range, 9e27) years) with SAK who underwent PVCR, were reviewed. Mean follow-up period was 32.2 (range, 24e64) months. Diagnosis of thepatients included congenital kyphosis in 11 patients, post-tuberculosis kyphosis in 3 patients andneuroŞbromatosis in 3 patients. The sagittal plane parameters (local kyphosis angle, lumbar lordosis,sagittal vertical axis, pelvic tilt, sacral slope and pelvic incidence) were measured in the preoperative andthe early postoperative periods and during the last follow-up on the lateral radiographs.Results: The mean preoperative localized kyphosis angle was 121.8(range, 101e149). The mean localkyphosis angle (LKA) was 71.5at postoperatively evaluation (p< 0.05). Complications were detected in12 patients (70.6%) with spinal shock in 4 patients, hemothorax in 3 patients, postoperative infection in 2patients, dural laceration in 2 patients, neurological deŞcit in 2 patients (1 paraplegia and 1 root injury),the shifted cage in 2 patients and rod fracture in 2 patients. Neurological events occurred in six patients(35%) with temporary neurological deŞcit in 5 patients and permanent neurological deŞcit in 1 patient.Conclusion: PVCR is an efŞcient and a successful technique for the correction of SAK. However, it can leadto a large number of major complications in SAK greater than 100.Level of evidence: Level IV, therapeutic study.Article THE ANALYSIS OF ELECTRON TRANSFER MECHANISM WITHIN FUEL CELL SYSTEMS: ELECTROCHEMICAL AND MICROBIAL APPROACHES(2023) Işılay BİLGİÇFuel cells are recognized for generating energy through electrochemical reactions while being environmentally friendly, as their only waste product is water. However, for these systems to achieve widespread commercial adoption, it's crucial to reduce the costs associated with catalysts used in the core of the system, known as the membrane-electrode assembly. Microbial fuel cells (MFCs) have gained attention as a promising avenue for alternative energy systems, offering a straightforward design and the ability to treat wastewater during energy production, thus sidestepping the use of fossil fuels. MFCs offer several advantages by employing inorganic molecules instead of traditional catalysts and microorganisms in lieu of enzymes. This study capitalizes on these benefits by utilizing Thiobacillus ferrooxidans, an oxidation bacteria, at the cathode, and a mixed culture of bacteria at the anode within the MFC. This approach leads to improved conductivity and overall system performance. The research delves into the fuel cell system's performance through electrochemical measurements. Furthermore, the study investigates the porphyrin structure of Thiobacillus ferrooxidans and unveils the electron transfer mechanism occurring at the cathode.Article An analysis of general surgery theses set up between years 1998-2018 in Turkey: Evidence levels and publication rates of 1996 theses(Turkish Surgical Assoc, 2020) Ferhatoglu, Murat Ferhat; Kivilcim, Taner; Kartal, Abdulcabbar; Filiz, Ali Llker; Kebudi, AbutObjective: Setting up and advocating a thesis is mandatory at the end of the residency training program to become a specialist in general surgery according to the regulations on medical specialization in Turkey. Writing a thesis helps the resident to learn to ask structured questions, assembling the most accurate study design, managing the study process, collecting the results and building a conclusion with medical implications. In this descriptive study, we aimed to investigate the publication rates of the theses written in the field of general surgery and to assess the properties of the published theses. Material and Methods: We performed an online search on September 1, 2018, about the theses of general surgery residents on the website of National Thesis data center of Academic Educational Board in Turkey including theses of medical residents in university-affiliated hospitals and analyzed theses accomplished between 1998-2018. The publication status of the theses was assessed by the entry of author name, the title of the theses and keywords of the theses by using the search engines of PubMed, Google Scholar and Turkish Academic Network and Information Center Turkish Database (ULAKBIM). Data were presented in a descriptive form as absolute numbers and percentages. Results: Between 1998-2018, 1996 theses were completed. 393 (20.5%) of these were published in a journal, and 288 (14.4%) were published in a journal indexed in SCI/SCIE. According to research methodologies, 79.2% of the experimental studies were published in SCI/SCIE indexed journals. Conclusion: Publication rates of the theses in the field of general surgery are low as they are in other specialties of medicine. This descriptive study might give an idea about the low scientific publication rates of general surgery theses. Further studies are needed to understand the underlying factors, which are responsible for this scant scientific performance.