TR Dizin İndeksli Yayınlar / TR Dizin Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14517/20

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Citation Count: 0
5th and 6th grade students' perceptions of communication
(Pegem Akad Yayincilik Egitim Danismanlik Hizmetleri Tic Ltd Sti, 2020) Duran, Aysemin; Duran, Aysemin; Eğitim Bilimleri / Educational Sciences
This study aims to examine how 5th and 6th grade students perceive the phenomenon of communication. It was designed as a qualitative research and the phenomenological method was used. Totally, 80 students constituted the study group. A two-part "Communication Perception Form" was created by the researchers in order to determine the perceptions of the students regarding the phenomenon of communication. Content analysis technique was used in evaluating the data obtained in this study. Data on the phenomenon of communication were gathered among five categories (nature, emotion, food, existence, tool/mediator). In the visual metaphors of the students, it was seen that they drew telephone and talking people mostly. The metaphors developed by the 5th and 6th graders, which are the first levels of secondary school, can be considered as important indicators for understanding the positive and negative effects of communication on students. In this study, where communication generally evokes speech or correspondence, it can be suggested that students acquire this skill in various fields through programs, since it is seen that students make more in-depth descriptions in visual expression.
Citation Count: 4
Aberrant socs3 promoter methylation as a noninvasive diagnostic biomarker for locally advanced prostate cancer;
(Logos Medical Publishing, 2020) Demircan Tan,B.; Yıldırım, Ali Osman; Yucel,B.; Altundag Kara,S.; Salman Yilmaz,S.; Yildirim,A.; Acil Tıp / Emergency Medicine
Objective: The aim of this study was to investigate the promoter methylation status of Rasassociated domain family 1A (RASSF1A), O-6-methylguanine-DNA methyltransferase (MGMT), Phosphatase with tensin homology (PTEN) and Suppressor of cytokine signaling 3 (SOCS3) tumor suppressor genes and evaluate the clinical utility of these genes as noninvasive, bloodbased epigenetic biomarkers for the diagnosis of Prostate Cancer (PCa). Method: A total of 41 consecutive patients and 10 healthy control groups were enrolled in the study. Pyrosequencing was performed to analyze the methylation levels of the promoter regions of the four tumor suppressor genes in patients compared to healthy controls. Results: The promoter methylation levels of RASSF1A, MGMT, PTEN and SOCS3 did not differ between the patient and control groups. However, SOCS3 promoter methylation level was significantly higher for patients having locally advanced PCa compared to those having localized PCa (p<0.05). Conclusion: Our results indicated that SOCS3 could be a useful, noninvasive blood-based epigenetic biomarker for the diagnosis of locally advanced PCa. © Istanbul Medeniyet University Faculty of Medicine.
Citation Count: 0
Acil Serviste Hasta Yakınları Öfke Seviyesi ve Düşünce Özellikleri İlişkisi: Pilot Çalışma
(2023) Erdoğan Taycan, Serap; Gündoğmuş, İbrahim; Taycan, Serap Erdoğan; Özdel, Kadir; Türkçapar, Mehmet Hakan; Usta, Dilara; Psikoloji / Pshchology
Şiddete yönelik müdahalelerin planlanması için mevcut çalışma acil servis bekleme salonundaki hasta yakınlarının öfke ve şiddete eğilimleri ile bilişsel çarpıtmaları arasındaki olası bağıntıların belirlenmesine odaklanmaktadır. Kesitsel tipteki mevcut çalışma acil servise başvuran hastaların çalışmaya katılmayı kabul eden 37 yakını ile gerçekleştirilmiştir. Katılımcılara Sosyodemografik veri formu, Sürekli Öfke-Öfke Tarz Ölçeği (SÖÖTÖ), Şiddet Eğilim Ölçeği, Düşünce Özellikleri Ölçeği (DÖÖ), Öznel Düşünceler İnanç Ölçeği (ÖDİÖ) ve Öznel Öfke ve Sıkıntı Ölçeği (ÖÖSÖ) uygulanmıştır. Çalışmaya dâhil edilen katılımcıların yaş ortalaması 31,83±10,35 yıldı ve 21’i (%56,8) kadındı. Düşünce özellikleri ölçeği “-meli, –malı ifade” ile SÖÖTÖ skoru ile arasında olumlu yönde istatiksel olarak anlamı bir korelasyon bulunmuştur (r=0,480, p=0,020). Düşünce özellikleri ölçeği “hep ya da hiç” alt boyutu ile ÖÖSÖ Sıkıntı skoru arasında olumlu yönde istatiksel olarak anlamı bir korelasyon bulunmuştur (r=0,445, p=0,038). Öznel öfke ve sıkıntı ölçeği Sıkıntı ve Öfke skorları arasında pozitif yönlü istatiksel olarak anlamlı bir ilişki saptanmıştır (r=0,830, p<0,001). Öznel düşünceler inanç ölçeği doktor skoru ile hemşire (r=0,694, p<0,001) ve sağlık personeli (r=0,546, p<0,001) skorları arasında ve hemşire ve sağlık personeli skorları (r=0,683, p<0,001) arasında pozitif yönde istatiksel olarak anlamı bir korelasyon bulunmuştur. Çalışmamız acil serviste hasta yakınlarının öfkeleri ile bilişsel çarpıtmalar arasında ilişki olduğunu ortaya koymuştur. Bu bağlamda sonuçlarımızın şiddet uygulayan bireylerin tanınmasında faydalı olacağı düşünülebilir. Bu konuya yönelik daha geniş örneklemli çalışmaların yapılmasının gerektiği açıktır.
Citation Count: 1
)actors affecting success in intrauterine insemination cycles 2-year single center e[perience
(2021) Gizem Berfin ULUUTKU; Rahime Nida BAYIK; İbrahim KALE; Başak ERGİN
Objective: The aim of this study is to evaluate the success rates of intrauterine insemination cycles due to ovulation induction with clomiphene citrate and gonadotropins, and to identify factors associated with successful outcomes in women with unexplained infertility and ovulatory dysfunction. Material and Methods: Between June 2017 and October 2019, 223 intrauterine insemination cycle records were scanned retrospectively in 152 infertile couples diagnosed with ovulatory dysfunction or unexplained infertility. Result: A total of 33 positive pregnancy test results were obtained, which had shown a pregnancy success rate of 14.8%. Pregnancy success rate in Gonadotropin IUI (Intrauterine Insemination) cycles was found as 16.6% and pregnancy success rate in CC (Clomiphene Citrate) IUI cycles was found as 9.3%. While it has been detected that smoking has had a negative effect on IUI success rate for the infertile population with ovulatory dysfunction and unexplained infertility (p=0.012); factors such as female age, BMI (Body mass index), infertility span, basal FSH (Follicle Stimulating Hormone), basal LH (Luteinizing Hormone), basal estradiol levels and trigger-day endometrial thickness were found to have no correlation with IUI success rate at all.
Citation Count: 0
Acute spinal epidural hematoma: A case report and review of the literature
(Turkish Assoc Trauma Emergency Surgery, 2020) Akar, Ezgi; Ogrenci, Ahmet; Koban, Orkun; Yilmaz, Mesut; Dalbayrak, Sedat
Spinal epidural hematoma (SEH) is a rare but a significant cause of spinal cord compression and neurologic deficits. Its etiology is usually unknown and requires emergency intervention. The present study aims to review the clinical significance, treatment strategies and clinical outcomes of traumatic SEH with a rare case presentation. Our patient was a 42-year-old female who presented with back pain and loss of sensation and strength in the legs. The patient did not have any disease and did not use anticoagulant drugs. The patient developed numbness in her legs half an hour after having a traditional back walking massage due to occasional back pain. She was paraplegic and anesthetic when seen in our clinic. Thoracic computed tomography (CT) and magnetic resonance imaging (MRI) revealed posterior epidural hemorrhage at Th3-Th4 levels. In the 12th hour, the hematoma was evacuated by an emergency decompressive hemilaminectomy. At the postoperative 24th hour, the patient had symptomatic improvement, and in the sixth month, the patient was mobilized with support. SEH is a rare condition that should be considered in patients with sudden onset of back pain and extremity weakness. Although the gold standard diagnostic tool is MRI, CT is often sufficient to avoid delayed surgery. Immediate surgical decompression (laminectomy/hemilaminectomy) should be performed in cases diagnosed with SEH with neurological deficits.
Citation Count: 0
Adaptation of COVID-19 risk perception and COVID-19 prevention guidelines compliance scales to Turkish: a validity and reliability study
(2021) Nazlı Kaya; Özlem Karatana; Emre İşçi
Aim: The aim of this study is to make Turkish adaptation and psychometric analysis of the COVID-19 Risk Perception and COVID-19 Prevention Guideline Compliance scales. Material and Method: The COVID-19 Risk Perception and COVID-19 Prevention Guideline Compliance scales administered to a total of 385 healthcare workers (Emergency medical technician, paramedic, ambulance driver etc.) and 50 healthcare workers were retested two weeks later. The opinions of 10 experts were taken for the content validity of the scale, the confirmatory factor analysis was performed for the construct validity, the Cronbach's alpha reliability coefficient was calculated to determine the internal consistency, and the test-retest reliability was performed and the results were evaluated with Pearson correlation analysis. Results: It can be concluded that an agreement among experts according to the results of the content validity index of the Turkish version of COVID-19 Risk Perception scale was found to be 0.91, the COVID-19 prevention guideline compliance scale was found to be 1. The test-retest reliability correlation of the scales was 0.85. Conclusion: COVID-19 Risk Perception and the COVID-19 prevention guideline compliance scales were suitable for Turkish culture, and they are valid and reliable.
Citation Count: 1
Adaptation of internal audit system to supervisory system in the provincial directorate of national education and a model proposal
(Pegem Akad Yayincilik Egitim Danismanlik Hizmetleri Tic Ltd Sti, 2020) Baris, Ali Erkan; Atanur Baskan, Gulsun
The aim of this research is to provide a supervision model for provincial directorates of national education in accordance with contemporary audit approaches. The study is designed as a mixed research method. The participants of the study include 4082 people; 3576 teachers, 452 administrators (10 provincial/district national education directors and assistant directors, 11 branch managers, 431 school principals and assistant principals) and 10 education supervisors working in public schools and institutions in Nevsehir in 2017 and 44 education supervisors working in the ministry of education. Data collection tools were developed by the researcher. The quantitative data were collected by the Adoption and Applicability Scale of the Internal Audit System (AASIAS). Qualitative data were collected through semi-structured interview form. Results of the study showed that the participants adopted the internal audit system to a great extent and found it applicable in provincial directorates of national education. In addition, the opinions of the participants were integrated into the internal audit system and a supervision model was developed for the purpose, structure and process dimensions of provincial directorates of national education.
Citation Count: 3
The Adaptation Study of The Metacognition, Self-efficacy and Learning Processes Scale into Turkish: Results of Confirmatory Factor Analysis
(2016) R. Suat IŞILDAK; M. Sabri KOCAKÜLAH; Mustafa ÇORAMIK; Erdoğan ÖZDEMİR.
This study involves the adaptation of a scale into Turkish which is developed by Thomas, Andersonand Nashon (2008) to investigate elements of students’ metacognition, self-efficacy and constructivist sciencelearning processes. In this context linguistic equivalence, validity and reliability analyses were conducted. Thescale was administered to 913 secondary school students aged between 15 and 18 years of age in four cities ofTurkey. Results of the confirmatory factor analyses [2(395, n=913)=1137.10, p<.000; RMSEA=.045;GFI=.92; CFI=.93; NNFI=.92] show that five factorial construct of the original scale was preserved in theTurkish form. Factor loadings differ from 0.50 to 0.70 for items and item-total score correlations ranged from0.39 to 0.65. The Cronbach alpha coefficient for whole scale was also calculated as 0.93.
Citation Count: 9
Adherence to guideline-directed medical and device Therapy in outpAtients with heart failure with reduced ejection fraction: The ATA study
(Turkish Soc Cardiology, 2020) Kocabas, Umut; Kivrak, Tarik; Oztekin, Gulsum Meral Yilmaz; Tanik, Veysel Ozan; Ozdemir, Ibrahim Halil; Kaya, Ersin; Pehlivanoglu, Seckin
Objective: Despite recommendations from heart failure guidelines on the use of pharmacologic and device therapy in patients with heart failure with reduced ejection fraction (HFrEF), important inconsistencies in guideline adherence persist in practice. The aim of this study was to assess adherence to guideline-directed medical and device therapy for the treatment of patients with chronic HFrEF (left ventricular ejection fraction <= 40%). Methods: The Adherence to guideline-directed medical and device Therapy in outpAtients with HFrEF (ATA) study is a prospective, multicenter, observational study conducted in 24 centers from January 2019 to June 2019. Results: The study included 1462 outpatients (male: 70.1%, mean age: 67 +/- 11 years, mean LVEF: 30%+/- 6%) with chronic HFrEF. Renin-angiotensin system (RAS) inhibitors, beta-blockers, mineralocorticoid receptor antagonists (MRAs), and ivabradin were used in 78.2%, 90.2%, 55.4%, and 12.1% of patients, respectively. The proportion of patients receiving target doses of medical treatments was 24.6% for RAS inhibitors, 9.9% for beta-blockers, and 10.5% for MRAs. Among patients who met the criteria for implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy (CRT), only 16.9% of patients received an ICD (167 of 983) and 34% (95 of 279) of patients underwent CRT (95 of 279). Conclusion: The ATA study shows that most HFrEF outpatients receive RAS inhibitors and beta-blockers but not MRAs or ivabradin when the medical reasons for nonuse, such as drug intolerance or contraindications, are taken into account. In addition, most eligible patients with HFrEF do not receive target doses of pharmacological treatments or guideline-recommended device therapy.
Citation Count: 0
AKUT MİYELOİD LÖSEMİDE SWITCH/SUKROZ FERMENTE EDILEMEZ KROMATİN YENİDEN ŞEKİLLENDİRME KOMPLEKSİNİN GENOMİK GÖRÜNÜMÜ
(2024) Özkan, Didem; Akın, Dilara Fatma; Tıbbi Laboratuvar Teknikleri / Medical Laboratory Techniques
SWI/SNF kromatin yeniden modelleme kompleksi, hematopoietik kök hücrelerde hücre bakımı ve farklılaşma gibi süreçler için gerekli olan gen ekspresyonunun düzenlenmesinde görev alır. Hematolojik süreçlerin homeostazında yer alan SWI/SNF kompleksi alt birimlerindeki değişiklikler hematolojik malignitelerin başlamasına veya ilerlemesine katkıda bulunmaktadır, ancak bu fenotipin arkasındaki mekanizmalar tam olarak açıklanmamıştır. Çalışmada, SWI/SNF kompleksini oluşturan genlerde mutasyonların ve ekspresyon profilinin biyoinformatik araçları kullanılarak kapsamlı belirlenmesi amaçlanmıştır. AML kohortuna (n:872) ait genom dizileri ve ifade profillerine biyoinformatik araçlar aracılığı ile elde edilmiş ve analiz edilmiştir. Kompleksin alt ünitelerini kodlayan 9 gende ARID1A, ARID1B, SMARCA2, SMARCA4, SMARCE1, SMARCB1, DPF2, PMBR1 ve BCL7A belirlenen mutasyonların AML patogenezinde onkojenik/patojenik etkilerinin tahmini PolyPhen-2, SIFT ve Mutation Assessor araçları kullanılmıştır. Mutasyona uğrayan proteinlerinin fonksiyenel etkilerini anlamak için STRING aracı ile analiz gerçekleştirilmiştir. Mutasyon profili değil aynı zamanda mutasyon varlığının gen ifadesi ve sağ kalım üzerine etkileride değerlendirilmiştir. 9 gende 9 yanlış anlam, 6 çerçeve kayması mutasyon, 1 splize bölge ve 1 füzyon mutasyonu olmak üzere toplam 17 genetik anormallik belirlenmiştir. AML kohortunda ARID1A, ARID1B, SMARCA2 ve PMBR1 ekspresyon seviyelerin hasta grubunda sağlıklı gruba yüksek ve istatistiksel olarak anlamlıdır (p<0.01). Düşük ve yüksek gen ekspresyon profillerine göre yapılan sağ kalım analizi sonuçlarımızda bir farklılık görülmemiştir. STRING analizinde, hedef genlerimizin, hücre döngüsü kontrolünde görev alan PHF10 ile fonksiyonel ilişkileri bulunduğu belirlenmiştir. Sonuç olarak, sonuçlarımız, ARID1A, ARID1B, SMARCA2, SMARCA4 ve PBRM1’de tespit ettiğimiz mutasyonlarının, SWI/SNF kromatin yeniden modelleme komplekslerinin fonksiyonunu bozarak AML patogenezi sırasında farklı kromatin ortamlarını içeren farklı hücresel yolları indükleyebileceği/inaktive edebileceğini düşündürmektedir.
Citation Count: 0
ALMANYA VE TÜRKİYE’DE SAĞLIKTA KALİTE İNDİKATÖRLERİ VE BEKLENMEYEN OLAY YAKLAŞIMLARI ÜZERİNE BİR DERLEME
(2024) Timlioğlu İper, Hatice Semrin; İper, Hatice Semrin Timlioğlu; Optisyenlik / Opticianry
Hasta güvenliğini sağlamak amacıyla kalite çalışmalarının değerlendirilmesi kalitenin ölçülmesi ile mümkün olmaktadır. Kalitenin ölçülmesi için “Kalite İndikatörleri” kullanılmaktadır. Kalite indikatörlerinin belirlenmesi ve gerçekçi ölçümlerin yapılabilmesi için ise bu indikatörler temelinde ortaya çıkmış olan beklenmeyen olayların tespit edilmesi ve bildirilmesi neticesinde kalitenin ölçülmesinin mümkün hale gelmesi sağlık sistemlerinin geliştirilmesi için çok değerli sonuçlar ortaya koymaktadır. Bu çalışmada “Sağlıkta Kalite Uygulamaları” kalite indikatörleri ve beklenmeyen olaylar odağında, Avrupa Birliği üyesi ve gelişmiş ülke konumundaki Almanya ile Avrupa Birliği yolunda ilerleyen ve gelişmekte olan bir ülke konumundaki Türkiyekarşılaştırılmıştır. Çalışmada Sağlıkta Kalite Uygulamalarının karşılaştırmalı değerlendirme neticesinde tanınması, iki ülkenin kalite indikatörleri ve beklenmeyen olaylara yaklaşımlarının olumlu ve olumsuz yönlerinin tartışılması ve uygulama güncellemeleri için alternatif olabilecek yöntemler önerilmesi amaçlanmıştır. Sonuç olarak; Almanya’da Kalite Programı “Geniş Katılımlı Veri Temelli Kalite Programı” olarak tanımlanabilir. Almanya’da Beklenmeyen Olay Bildirimleri için hastaneler özendirilmekte, kaliteye yöneltilmekte, sağlık hizmetinde kalite rekabeti oluşturulmaktadır. Ancak ödemeler ve finansal kaygılar göz önüne alındığında bu rekabetin sadece kalite göstergelerinin halka ulaştırılmasıyla sağlanamayacağı hissedilmektedir. Türkiye’de kalite indikatörlerinin kullanılmasını sağlayacak sistemde çok iyi bir seviye yakalanmış olmasına rağmen beklenmeyen olay bildirimi, kalite indikatörlerinin işletilmesi ve sonuçların paylaşılması hususlarında aksaklıklar hissedilmektedir.
Citation Count: 0
Ambiguus Genitalya ve Böbrek Agenezisi ile Birlikte Görülen Heterofagusun en Nadir Formu Olan İskiofagus Vakası
(2020) Çalışkan, Eray; Haqverdiyev, Emin; Akar, Bertan; Gümüştaş, Gokhan; Aslancan, Reyhan
Parazit iki kiz parsiyel olarak rezorbe olmuş ve normal fetus üzerinde yerleşmiş inkomplet fetüsü tariflemek için kullanılan bir terimdir. İskiofagus normal fetuse ileumdan bağlanmış parazitik fetüsü ifade edip parazit ikiz vakalarının en nadir görülen formudur. Bu vakada on üç haftalık fetus birinci trimester ultrasonografik incelemesinde iskiofagus, ambiguus genitalya ve böbrek agenezisi tanısı almıştır. Ailenin kararı sonucu terminasyon uygulanmıştır. Parazitik ikiz vakaları eşlik edebilecek multisistemik anomaliler açısından dikkatli incelenmelidir. Aileyi fetüsün durumunun yaşamla bağdaşırlığı açısından bilgilendirmek gereksiz terminasyonları önlemek açısından önemlidir.
Citation Count: 0
Analysis of a Prefabricated Vertical Drain (PVD) Soil Improvement Project
(Turkish Chamber Civil Engineers, 2022) Mert, Ahmet Can; Onalp, Akin; Arel, Ersin
A settlement analysis has been carried out for several sectors of a rail station yard improved with prefabricated vertical drains (PVD) in Istanbul, that exhibited prolonged consolidation beyond the predicted values in certain sectors of the treated zone. Final settlement and End of Primary (EOP) settlement times have been estimated theoretically as well as using the Asaoka graphical procedure. The compliance of settlement-time curves with in-situ measurements and Asaoka solution has been investigated. A geotechnical model was developed for finite element and three-dimensional consolidation analyses. The settlement curves obtained by varying horizontal-vertical permeability coefficient ratio (k(h)/k(v)) and in-situ measurements have been compared, and k(h)/k(v) values corresponding to 90% degree of consolidation has been computed for all sectors. The effect of drain spacing (S-drain) as well as drain length (L-drain) on the rate of consolidation have been evaluated for each sector, keeping the specified ratios constant. The times corresponding to 95% degree of consolidation (t(95)) have been calculated using the theoretical solution and compared to in-situ measurements. Calculated t(95)'s has also been compared to their estimated values by varying the spacing (S-drain) and the length (L-drain). Additionally, the required intervals of S-drain and L-drain have been obtained corresponding to the calculated t(95) times. The analyses suggest that the main reason for prolonged consolidation was the horizontal to vertical permeability coefficient ratio. According to the analysis results, PVD implementation was not efficient in clays having k(h)/k(v) of approximately unity. The main conclusion of this study was to discover the necessity for optimizing the variables in any such project. The efficacy of the works can be significantly enhanced if simultaneous evaluation of the parameters S-drain and L-drain and the permeability ratio k(h)/k(v) is carried out prior to field work. Otherwise, "accidents" may emerge as found out in this project.
Citation Count: 0
Analysis of complications following posterior vertebral column resection for the treatment of severe angular kyphosis greater than 100
(2017) Balioğlu, Mehmet Bülent; Albayrak, Akif; Atıcı, Yunus; Kargın, Deniz; Mert, Muhammed; Kaygusuz, Mehmet Akif
Objective: The aim of this study was to evaluate the complications, efŞcacy and safety of posteriorvertebral column resection (PVCR) in severe angular kyphosis (SAK) greater than 100.Methods: The medical records of 17 patients (mean age 17.9 (range, 9e27) years) with SAK who underwent PVCR, were reviewed. Mean follow-up period was 32.2 (range, 24e64) months. Diagnosis of thepatients included congenital kyphosis in 11 patients, post-tuberculosis kyphosis in 3 patients andneuroŞbromatosis in 3 patients. The sagittal plane parameters (local kyphosis angle, lumbar lordosis,sagittal vertical axis, pelvic tilt, sacral slope and pelvic incidence) were measured in the preoperative andthe early postoperative periods and during the last follow-up on the lateral radiographs.Results: The mean preoperative localized kyphosis angle was 121.8(range, 101e149). The mean localkyphosis angle (LKA) was 71.5at postoperatively evaluation (p< 0.05). Complications were detected in12 patients (70.6%) with spinal shock in 4 patients, hemothorax in 3 patients, postoperative infection in 2patients, dural laceration in 2 patients, neurological deŞcit in 2 patients (1 paraplegia and 1 root injury),the shifted cage in 2 patients and rod fracture in 2 patients. Neurological events occurred in six patients(35%) with temporary neurological deŞcit in 5 patients and permanent neurological deŞcit in 1 patient.Conclusion: PVCR is an efŞcient and a successful technique for the correction of SAK. However, it can leadto a large number of major complications in SAK greater than 100.Level of evidence: Level IV, therapeutic study.
Citation Count: 0
THE ANALYSIS OF ELECTRON TRANSFER MECHANISM WITHIN FUEL CELL SYSTEMS: ELECTROCHEMICAL AND MICROBIAL APPROACHES
(2023) Işılay BİLGİÇ
Fuel cells are recognized for generating energy through electrochemical reactions while being environmentally friendly, as their only waste product is water. However, for these systems to achieve widespread commercial adoption, it's crucial to reduce the costs associated with catalysts used in the core of the system, known as the membrane-electrode assembly. Microbial fuel cells (MFCs) have gained attention as a promising avenue for alternative energy systems, offering a straightforward design and the ability to treat wastewater during energy production, thus sidestepping the use of fossil fuels. MFCs offer several advantages by employing inorganic molecules instead of traditional catalysts and microorganisms in lieu of enzymes. This study capitalizes on these benefits by utilizing Thiobacillus ferrooxidans, an oxidation bacteria, at the cathode, and a mixed culture of bacteria at the anode within the MFC. This approach leads to improved conductivity and overall system performance. The research delves into the fuel cell system's performance through electrochemical measurements. Furthermore, the study investigates the porphyrin structure of Thiobacillus ferrooxidans and unveils the electron transfer mechanism occurring at the cathode.
Citation Count: 9
An analysis of general surgery theses set up between years 1998-2018 in Turkey: Evidence levels and publication rates of 1996 theses
(Turkish Surgical Assoc, 2020) Ferhatoglu, Murat Ferhat; Kivilcim, Taner; Kartal, Abdulcabbar; Filiz, Ali Llker; Kebudi, Abut
Objective: Setting up and advocating a thesis is mandatory at the end of the residency training program to become a specialist in general surgery according to the regulations on medical specialization in Turkey. Writing a thesis helps the resident to learn to ask structured questions, assembling the most accurate study design, managing the study process, collecting the results and building a conclusion with medical implications. In this descriptive study, we aimed to investigate the publication rates of the theses written in the field of general surgery and to assess the properties of the published theses. Material and Methods: We performed an online search on September 1, 2018, about the theses of general surgery residents on the website of National Thesis data center of Academic Educational Board in Turkey including theses of medical residents in university-affiliated hospitals and analyzed theses accomplished between 1998-2018. The publication status of the theses was assessed by the entry of author name, the title of the theses and keywords of the theses by using the search engines of PubMed, Google Scholar and Turkish Academic Network and Information Center Turkish Database (ULAKBIM). Data were presented in a descriptive form as absolute numbers and percentages. Results: Between 1998-2018, 1996 theses were completed. 393 (20.5%) of these were published in a journal, and 288 (14.4%) were published in a journal indexed in SCI/SCIE. According to research methodologies, 79.2% of the experimental studies were published in SCI/SCIE indexed journals. Conclusion: Publication rates of the theses in the field of general surgery are low as they are in other specialties of medicine. This descriptive study might give an idea about the low scientific publication rates of general surgery theses. Further studies are needed to understand the underlying factors, which are responsible for this scant scientific performance.
Citation Count: 0
The Analysis of Investment Decisions of Foreign Exchange Investors from the Perspective of Behavioral Finance
(2020) Turgay MÜNYAS; Münyas, Turgay; Uluslararası Finans / International Finance
Behavioral finance is a multidisciplinary sub-branch of finance that seeks to explain the financial decisions of investors by taking advantage of different fields such as sociology, psychology and anthropology. The purpose of this research is to examine the behaviors of the individual foreign exchange investor from the perspective of behavioral finance. In the study, the behaviors of individual foreign exchange investors were studied under five dimensions: overconfidence, overoptimism, regret aversion, loss aversion, and representative bias. A total of 319 individual foreign exchange investors was surveyed in order to investigate the relationship in question. This study investigates the difference in the behaviors of individual foreign exchange investors in terms of marital status, age, education level, professional experience, frequency of reviewing the investments, the most frequently used sources of information while making decisions about the investments, the most common methods used for the preference of investment instruments, the main factors considered in the preference of the investment instruments, the amount of capital, and personality traits. The research findings are discussed in the conclusion section.
Citation Count: 0
Analysis of Protein C Inhibitor/ SERPINA5
(2020) Nejat AKAR; Didem TORUN ÖZKAN
Protein C inhibitor is a non-specific serine protease inhibitor with extensive protease reactivity. Protein C inhibitor (SERPINA5, plasminogen activator inhibitor-3/PAI-3) is a secreted, extracellular clade A serpin. SERPINA5/PCI has originally been described as an inhibitor of activated protein C and independently as an inhibitor of the plasminogen activator urokinase. SERPINA5 binds glycosaminoglycans, phospholipids, and retinoic acid. Glycosaminoglycans and certain phospholipids can modulate its inhibitory activity and specificity. PCI plays role at thrombosis and fibrinolysis, regulation of fertilization, tissue regeneration, vascular permeability, tumor development, invasion, metastasis and angiogenesis. In this review; aimed to provide information about the functions of PCI and to provide guidance for studies.
Citation Count: 0
Analyzing The Relationship Between The Physician Assistants’ Perceptions of Mentorship and Their Self-Efficacy: A Sample From Izmir Province
(2020) Gülhan, Yıldırım Beyazıt; Yıldız TEZEL BAYDAR; Aysun DANAYİYEN; Sağlık Yönetimi / Healthcare Management
Objective: Mentors are assigned to physician assistants by the heads of departments they work in after they start their duty. This study seeks to reveal physician assistants’ per-ceptions towards their mentors and the relationship be-tween their such perceptions and self-efficacy.Materials and Methods: The population of this study covers physician assistants working in Ege University Hos-pital, Izmir Atatürk Training and Research Hospital, and Izmir Tepecik Training and Research Hospital. 436 of them were reached within the scope of the study. The sur-vey method was used for data collection to measure physi-cian assistants’ perceptions of mentorship and self-efficacy. The data were analyzed using SPSS 22.0.Results: The physicians working in the training and re-search hospitals have a significantly higher Mentoring Functions Scale total score, significantly higher score for acceptance and confirmation, significantly higher score for sponsorship, and significantly higher score for exposure and visibility compared to the physicians working in the university hospital (p<0.05). The correlation analysis con-ducted between the Mentoring Functions Scale and the Self-Efficacy Scale indicated that there is a relationship be-tween all the sub-factors except for the role modeling sub-factor of the Mentoring Functions Scale and the willing-ness to initiate a behavior sub-factor of the Self-Efficacy Scale.Conclusions: In this study, as relationships were detected between persistence in the face of adversity (self-efficacy) and coaching and acceptance and confirmation (mentoring). Benefiting from the positive role models in physician assistants’ social milieu may not initiate a behav-ior but it helps to maintain a behavior.
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Anaplastic thyroid carcinoma case series
(2024) Üyetürk, Ümmügül; Duman, Tuba Taslamacıoğlu; Düzcü, Selma Erdoğan; Rahatlı, Samed; Üyetürk, Ümmügül; Medikal Onkoloji / Medical Oncology
Aim: Among the endocrine malignancies, thyroid carcinoma (TC) is the most common. However, anaplastic TC accounts for 1-2% of these cancers. The aim of this study was to evaluate the demographic and pathologic features, treatments, and survival of patients with anaplastic TC. Methods: Anaplastic TC patients who applied to our medical oncology clinics between 01.01.2012 -01.12.2018 were retrospectively evaluated. Results: A total of 8 patients were included in the study. There were 4 female and 4 male patients with a median age of 68 (minimum 61-maximum 83) years. The initial complaint of all patients was a fast-growing swelling in the neck. Six patients had total thyroidectomy. Two patients had anaplastic TC with a differential TC. Six patients were at stage 4C. The most common site of metastasis was the lung (75%). Five patients had received a median of 3 (1-6) cycles of chemotherapy. Radiotherapy was applied to 7 patients. All patients except one died during the follow-up period. The median survival time of the patients was 3 (2-15) months. Conclusion: Anaplastic TC, an aggressive tumor with high metastasic potential, has no effective treatment at present. Effective treatments are needed for this rare and aggressive disease. Developments in the molecular field are promising for the treatment of ATC.

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