Investigation of antioxidant capacity, bioaccessibility and LC-MS/MS phenolic profile of Turkish propolis

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dc.authoridOzdal, Tugba/0000-0001-8344-5336
dc.authoridCeylan, Fatma Duygu/0000-0002-2858-2482
dc.authoridKaplan, Muammer/0000-0002-8312-5479
dc.authoridCapanoglu, Esra/0000-0003-0335-9433
dc.authorscopusid55628003500
dc.authorscopusid57202497708
dc.authorscopusid57194272564
dc.authorscopusid7403264862
dc.authorscopusid56166763900
dc.authorscopusid23666338900
dc.authorwosidOzdal, Tugba/B-5799-2018
dc.authorwosidCeylan, Fatma Duygu/AAA-2588-2020
dc.authorwosidKaplan, Muammer/I-2261-2019
dc.authorwosidCapanoglu, Esra/A-4455-2018
dc.contributor.authorOzdal, Tugba
dc.contributor.authorCeylan, Fatma Duygu
dc.contributor.authorEroglu, Nazife
dc.contributor.authorKaplan, Muammer
dc.contributor.authorOlgun, Elmas Oktem
dc.contributor.authorCapanoglu, Esra
dc.date.accessioned2024-05-25T11:41:16Z
dc.date.available2024-05-25T11:41:16Z
dc.date.issued2019
dc.departmentOkan Universityen_US
dc.department-temp[Ozdal, Tugba] Istanbul Okan Univ, Fac Engn, Dept Food Engn, TR-34959 Istanbul, Turkey; [Ceylan, Fatma Duygu; Capanoglu, Esra] Istanbul Tech Univ, Fac Chem & Met Engn, Dept Food Engn, TR-34469 Istanbul, Turkey; [Eroglu, Nazife; Kaplan, Muammer] TUBITAK Marmara Res Ctr, Inst Chem Technol, TR-41470 Kocaeli, Turkey; [Olgun, Elmas Oktem] TUBITAK Marmara Res Ctr, Environm & Cleaner Prod Inst, TR-41470 Kocaeli, Turkey; [Eroglu, Nazife] ALCON, Vis Care R&D, 11460 Johns Creek Pkwy, Duluth, GA 30097 USAen_US
dc.descriptionOzdal, Tugba/0000-0001-8344-5336; Ceylan, Fatma Duygu/0000-0002-2858-2482; Kaplan, Muammer/0000-0002-8312-5479; Capanoglu, Esra/0000-0003-0335-9433en_US
dc.description.abstractPropolis is a resinous bee hive product that has many biological activities. In this study, a total of 11 raw propolis samples were collected from various geographical areas in Turkey. Phenolic compounds were extracted from all samples and analyses of total phenolics and flavonoids and total antioxidant capacities were performed. All the samples showed high total phenolic and flavonoid contents and antioxidant capacities. Moreover, the in vitro bioaccessibility of Turkish propolis samples were investigated according to simulated in vitro gastrointestinal digestion method. Bioaccessibility was increased through the gastric and intestinal phases. Furthermore, the composition of polyphenols (phenolic acids and flavonoids) in Turkish propolis extracts was investigated by LC-MS/MS method. A total of 32 phenolic compounds, including Caffeic acid phenylethyl ester (CAPE) which was observed in all samples, were identified in the samples. Higher CAPE contents were determined in the samples from the Marmara region which is in line with its higher antioxidant capacity values. As a conclusion, propolis samples collected from different geographical locations differ for their phenolic and flavonoid contents, individual phenolic profile and bioaccessibility.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK), BIDEB-2232 Project [113C036, 5134103]en_US
dc.description.sponsorshipThis study was fully supported by the Scientific and Technological Research Council of Turkey (TUBITAK), BIDEB-2232 Project No: 113C036, Institution Code: 5134103 under the name of "Investigation of important honeybee, Apis mellifera L. (Hymenoptera, Apidae), subspecies and ecotypes in Turkey considering propolis collection capacity and chemical characterization of Turkish propolis.en_US
dc.identifier.citation67
dc.identifier.doi10.1016/j.foodres.2019.05.028
dc.identifier.endpage536en_US
dc.identifier.issn0963-9969
dc.identifier.issn1873-7145
dc.identifier.pmid31229108
dc.identifier.scopus2-s2.0-85066126064
dc.identifier.scopusqualityQ1
dc.identifier.startpage528en_US
dc.identifier.urihttps://doi.org/10.1016/j.foodres.2019.05.028
dc.identifier.urihttps://hdl.handle.net/20.500.14517/1504
dc.identifier.volume122en_US
dc.identifier.wosWOS:000473379200055
dc.identifier.wosqualityQ1
dc.language.isoen
dc.publisherElsevieren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPropolisen_US
dc.subjectPhenolic compoundsen_US
dc.subjectAntioxidant capacityen_US
dc.subjectIn vitro gastrointestinal digestionen_US
dc.subjectBioaccessibilityen_US
dc.subjectLC-MS/MSen_US
dc.titleInvestigation of antioxidant capacity, bioaccessibility and LC-MS/MS phenolic profile of Turkish propolisen_US
dc.typeArticleen_US
dspace.entity.typePublication

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