Adaptation of Ventilation Strategies From Acute RDS To Severe BPD a National Multicenter Survey of Practices in Extremely Preterm Infants

dc.authorscopusid 58764103800
dc.authorscopusid 24773951700
dc.authorscopusid 7003310394
dc.authorscopusid 26026246200
dc.authorscopusid 57755613800
dc.authorscopusid 7004606858
dc.authorscopusid 59405263900
dc.contributor.author Akyıldız, C.
dc.contributor.author Tüzün, F.
dc.contributor.author Duman, N.
dc.contributor.author Akcan, A.B.
dc.contributor.author Ünkar, Z.A.
dc.contributor.author Aygün, C.
dc.contributor.author Özkan, H.
dc.date.accessioned 2025-06-15T22:09:07Z
dc.date.available 2025-06-15T22:09:07Z
dc.date.issued 2025
dc.department Okan University en_US
dc.department-temp [Akyıldız C.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey; [Tüzün F.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey; [Duman N.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey; [Akcan A.B.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Adnan Menderes University Medical School, Aydın, Turkey; [Ünkar Z.A.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Istanbul University-Cerrahpaşa, Istanbul, Turkey; [Aygün C.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey; [Bozdağ Ş.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, İstanbul Okan University, Istanbul, Turkey; [Bozkurt Ö.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey; [Bulut Ö.] Department of Pediatrics, Division of Neonatology, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey; [Bülbül A.] Department of Pediatrics, Division of Neonatology, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey; [Büyükeren M.] Department of Pediatrics, Division of Neonatology, Konya City Hospital, Konya, Turkey; [Büyükkale G.] Department of Pediatrics, Division of Neonatology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey; [Çelik Y.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Mersin University, Mersin, Turkey; [Çelik İ.H.] Department of Pediatrics, Division of Neonatology, University of Health Sciences Türkiye, Etlik Zübeyde Hanım Women’s Health Teaching and Research Hospital, Ankara, Turkey; [Çetin H.] Department of Pediatrics, Division of Neonatology, Medical Faculty, Suleyman Demirel University, Isparta, Turkey; [Çetinkaya M.] Department of Pediatrics, Division of Neonatology, Health Sciences University, Başaksehir. Cam and Sakura City Hospital, Istanbul, Turkey; [Çoban D.] Department of Pediatrics, Division of Neonatology, Atatürk Sanatoryum Training and Research Hospital, University of Health Sciences, Ankara, Turkey; [Egeli T.] Department of Pediatrics, Division of Neonatology, İzmir City Hospital, Izmir, Turkey; [Gökmen Z.] Department of Pediatrics, Division of Neonatology, Medical Faculty of Baskent University, Konya, Turkey; [İlhan Ö.] Department of Pediatrics, Division of Neonatology, Mugla Sitki Kocman University School of Medicine, Mugla, Turkey; [İşleyen F.] Department of Pediatrics, Division of Neonatology, Şanlıurfa Training and Research Hospital, University of Health Sciences, Şanlıurfa, Turkey; [Kader Ş.] Department of Pediatrics, Division of Neonatology, Kırklareli Training and Research Hospital, University of Health Sciences, Kırklareli, Turkey; [Kahveci H.] Department of Pediatrics, Division of Neonatology, University of Health Sciences Erzurum, Medical Faculty, Erzurum, Turkey; [Kanmaz G.] Department of Pediatrics, Division of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey; [Karadeniz L.] Department of Pediatrics, Division of Neonatology, Istanbul University, İstanbul, Turkey; [Karagöl B.S.] Department of Pediatrics, Division of Neonatology, Gulhane Medicine Faculty, University of Health Sciences, Ankara, Turkey; [Narlı N.] Department of Pediatrics, Division of Neonatology, Cukurova University, Adana, Turkey; [Okulu E.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Ankara University, Ankara, Turkey; [Ongun H.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Akdeniz University, Antalya, Turkey; [Özdemir M.] Department of Pediatrics, Division of Neonatology, Mardin Training and Research Hospital, University of Health Sciences, Mardin, Turkey; [Özdemir Ö.M.A.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Pamukkale University, Denizli, Turkey; [Özdemir A.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Erciyes University, Kayseri, Turkey; [Özkan H.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Uludag University, Bursa, Turkey; [Şimşek H.] Department of Pediatrics, Division of Neonatology, Mersin Training and Research Hospital, University of Health Sciences, Mersin, Turkey; [Tanrıverdi S.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey; [Tarakçı N.] Department of Pediatrics, Division of Neonatology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey; [Tekgündüz K.Ş.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Atatürk University, Erzurum, Turkey; [Terek D.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Ege University, Izmir, Turkey; [Uygur Ö.] Department of Pediatrics, Division of Neonatology, İzmir Tepecik Training and Research Hospital, University of Health Sciences, Izmir, Turkey; [Varal İ.G.] Department of Pediatrics, Division of Neonatology, Bursa Yuksek Ihtisas Training and Research Hospital, University of Health Sciences, Bursa, Turkey; [Yıldırım T.G.] Department of Pediatrics, Division of Neonatology, H.S.U. Dr. Behcet Uz Children’s Education and Research Hospital, University of Health Sciences, Izmir, Turkey; [Özkan H.] Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey en_US
dc.description.abstract Advances in diagnostic and therapeutic methods have led to a paradigm shift in the management of bronchopulmonary dysplasia (BPD). The lack of evidence-based data in this area has led to variations in clinical practice. The aim of this study was to identify these differences and compare them with recommendations based on pathophysiology. The study was designed as an observational online survey of neonatologists from level 3 to 4 neonatal intensive care units caring for premature infants at increased risk of BPD and born before 28 weeks’ gestation. Respondents were invited to participate in the study through the portal of the Turkish Neonatal Society. Participants were surveyed online about preferred ventilation modes, settings and clinical management of these patients through each respiratory distress syndrome, evolving BPD and severe BPD phases. A total of 39 centers involved in the study. Pressure-control assist-control volume-guaranteed was the most commonly preferred ventilation mode in respiratory distress syndrome and evolving BPD, while high frequency oscillatory ventilation was most commonly used in severe BPD. The use of synchronized intermittent mandatory ventilation volume-guaranteed pressure support ventilation increased with disease progression. Ventilation settings were found to be changed according to pathophysiological recommendations, but not to the extent recommended. The study shows that early ventilation strategies are predominantly maintained in the later phases of BPD, although there are notable differences between centers. Copyright © 2025 the Author(s). Published by Wolters Kluwer Health, Inc. en_US
dc.identifier.doi 10.1097/MD.0000000000041973
dc.identifier.issn 0025-7974
dc.identifier.issue 22 en_US
dc.identifier.scopus 2-s2.0-105006926449
dc.identifier.scopusquality Q2
dc.identifier.uri https://doi.org/10.1097/MD.0000000000041973
dc.identifier.uri https://hdl.handle.net/20.500.14517/8020
dc.identifier.volume 104 en_US
dc.identifier.wosquality Q3
dc.language.iso en en_US
dc.publisher Lippincott Williams and Wilkins en_US
dc.relation.ispartof Medicine (United States) en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Bronchopulmonary Dysplasia en_US
dc.subject Extremely Premature Infant en_US
dc.subject High Frequency Ventilation en_US
dc.subject Noninvasive Ventilation en_US
dc.subject Positive Pressure Respiration en_US
dc.subject Respiratory Distress Syndrome en_US
dc.title Adaptation of Ventilation Strategies From Acute RDS To Severe BPD a National Multicenter Survey of Practices in Extremely Preterm Infants en_US
dc.type Article en_US

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