EFFECTS OF ULTRASOUND-ASSISTED PRECONDITIONING ON CRITICALLY ISCHEMIC SKIN FLAPS: AN EXPERIMENTAL STUDY

dc.authorid Unverdi, Omer Faruk/0000-0001-8560-7300
dc.authorscopusid 57212668744
dc.authorscopusid 6603804780
dc.authorscopusid 57189899199
dc.authorwosid Unverdi, Omer Faruk/HLH-0757-2023
dc.authorwosid Yucel, Sercan/AAM-6053-2021
dc.contributor.author Yucel, Sercan
dc.contributor.author Gunay, Galip Kemali
dc.contributor.author Unverdi, Omer Faruk
dc.date.accessioned 2024-05-25T11:40:14Z
dc.date.available 2024-05-25T11:40:14Z
dc.date.issued 2020
dc.department Okan University en_US
dc.department-temp [Yucel, Sercan; Gunay, Galip Kemali] Erciyes Univ, Sch Med, Dept Plast Reconstruct & Aesthet Surg, TR-38030 Kayseri, Turkey; [Unverdi, Omer Faruk] Istanbul Okan Univ, Sch Med, Dept Plast Reconstruct & Aesthet Surg, Aydinli Yolu Caddesi,Aydemir Sk 2, TR-34947 Istanbul, Turkey en_US
dc.description Unverdi, Omer Faruk/0000-0001-8560-7300; en_US
dc.description.abstract This study evaluates the effect of ultrasound-assisted preconditioning on critically ischemic flaps. Ninety-eight Sprague Dawley rats were randomly divided into eight groups. Control, surgical delay, ultrasound and sham groups were designed. Modified McFarlane flaps were raised on the back of rats, and flap survival rate was assessed on post-operative day 14 in control, ultrasound and sham groups. Bipedicled flaps were created in the surgical delay group, and 14 d after delaying, all skin flaps were elevated. Statistically, flap survival rates of all ultrasound groups were significantly higher than the control group. Plasma vascular endothelial growth factor levels were increased in all ultrasound groups. Vessel counts did not show any difference between the groups. This study shows that the preconditioning by ultrasound can be used to improve the viability of ischemic skin flaps almost at a level close to the surgical delay. (C) 2019 World Federation for Ultrasound in Medicine & Biology. All rights reserved. en_US
dc.description.sponsorship Scientific Research Projects Unit of Erciyes University [TTU-2015-6151] en_US
dc.description.sponsorship The authors would like to thank to Dr. Kemal Deniz, Erciyes University School of Medicine, for the histopathologic assessments. The authors are grateful for the financial support of The Scientific Research Projects Unit of Erciyes University (TTU-2015-6151). en_US
dc.identifier.citationcount 0
dc.identifier.doi 10.1016/j.ultrasmedbio.2019.12.009
dc.identifier.endpage 666 en_US
dc.identifier.issn 0301-5629
dc.identifier.issn 1879-291X
dc.identifier.issue 3 en_US
dc.identifier.pmid 31924418
dc.identifier.scopus 2-s2.0-85077660150
dc.identifier.scopusquality Q2
dc.identifier.startpage 660 en_US
dc.identifier.uri https://doi.org/10.1016/j.ultrasmedbio.2019.12.009
dc.identifier.uri https://hdl.handle.net/20.500.14517/1419
dc.identifier.volume 46 en_US
dc.identifier.wos WOS:000512920900018
dc.identifier.wosquality Q2
dc.language.iso en
dc.publisher Elsevier Science inc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.scopus.citedbyCount 0
dc.subject Skin flap en_US
dc.subject Ultrasound en_US
dc.subject Preconditioning en_US
dc.subject VEGF en_US
dc.subject Necrosis en_US
dc.subject Surgical delay en_US
dc.title EFFECTS OF ULTRASOUND-ASSISTED PRECONDITIONING ON CRITICALLY ISCHEMIC SKIN FLAPS: AN EXPERIMENTAL STUDY en_US
dc.type Article en_US
dc.wos.citedbyCount 0

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