Case Report: presentation of pleomorphic liposarcoma arising in a borderline phyllodes tumor

dc.authorid GUNES, GOZDE/0000-0003-0991-1380
dc.authorid APA, DUYGU DÜŞMEZ/0000-0002-9984-2026
dc.authorscopusid 6508229477
dc.authorscopusid 55765961400
dc.authorscopusid 57204845066
dc.authorscopusid 56803739400
dc.authorwosid GUNES, GOZDE/G-4374-2017
dc.authorwosid APA, DUYGU DÜŞMEZ/A-4977-2019
dc.contributor.author Polat, Yalcin
dc.contributor.author Arslan, Gozde
dc.contributor.author Kebudi, Abud
dc.contributor.author Apa, Duygu Dusmez
dc.date.accessioned 2024-05-25T11:19:10Z
dc.date.available 2024-05-25T11:19:10Z
dc.date.issued 2018
dc.department Okan University en_US
dc.department-temp [Polat, Yalcin; Apa, Duygu Dusmez] Univ Biruni, Fac Med, Dept Pathol, Protokol Yolu 45,10 Yil Cd, TR-34010 Istanbul, Turkey; [Arslan, Gozde] Univ Maltepe, Fac Med, Dept Radiol, Univ Med Fac, Dept Feyzullah Cad 39, TR-34843 Istanbul, Turkey; [Kebudi, Abud] Univ Okan, Fac Med, Dept Gen Surg, Aydinli Yolu Cad,Aydemir Sk 2, TR-34947 Istanbul, Turkey en_US
dc.description GUNES, GOZDE/0000-0003-0991-1380; APA, DUYGU DÜŞMEZ/0000-0002-9984-2026 en_US
dc.description.abstract INTRODUCTION: The stromal component of Phyllodes tumors represents the neoplastic portion of the lesion. A variety of associated malignancies can arise from PTs, with its dual population of cells. PRESENTATION OF CASE: We share a very rare case of "borderline"breast phillodes tumour with a 75% liposarcoma component. A 48-year-old woman presented at the surgical clinic with a mass in the left breast. On mammograms, the lesion was dense with radiolucent areas inside which were thought to be compatible with fat. The mass was assumed to be breast imaging-reporting and data system (BIRADS) 3 on sonography as it was well contoured. The needle biopsy was reported to be consistent with a fibroadenomatous lesion. The lesion was completely excised. On microscopic examination, the lesion has benign mammary duct epithelium lining the slit-like spaces. The stroma composed of fibrous and adipous tissue. The fibrous part was cellular, and several cells appeared bizarre. Adipous tissue replaced most of the stroma and was diagnosed as pleomorphic liposarcoma. DISCUSSION: According to the 3 tiered grading criteria of PTs, our case normally suits in borderline category, without liposarcoma component. Heterologous sarcomatous elements usually accompany high grade PTs. Rare cases of benign and borderline PTs with sarcoma component have been reported. CONCLUSION: The presence of a malignant heterologous component places the tumour into the malignant category regardless of other histological features. (C) 2018 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. en_US
dc.identifier.citationcount 3
dc.identifier.doi 10.1016/j.ijscr.2018.10.038
dc.identifier.endpage 494 en_US
dc.identifier.issn 2210-2612
dc.identifier.pmid 30567077
dc.identifier.scopus 2-s2.0-85057447706
dc.identifier.scopusquality Q3
dc.identifier.startpage 490 en_US
dc.identifier.uri https://doi.org/10.1016/j.ijscr.2018.10.038
dc.identifier.uri https://hdl.handle.net/20.500.14517/376
dc.identifier.volume 53 en_US
dc.identifier.wos WOS:000452767800122
dc.language.iso en
dc.publisher Elsevier Sci Ltd en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.scopus.citedbyCount 2
dc.subject Case report en_US
dc.subject Breast en_US
dc.subject Histopathology en_US
dc.subject Liposarcoma en_US
dc.subject Philloides tumor en_US
dc.title Case Report: presentation of pleomorphic liposarcoma arising in a borderline phyllodes tumor en_US
dc.type Article en_US
dc.wos.citedbyCount 2

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