Investigation of antioxidant capacity, bioaccessibility and LC-MS/MS phenolic profile of Turkish propolis

dc.authorid Ozdal, Tugba/0000-0001-8344-5336
dc.authorid Ceylan, Fatma Duygu/0000-0002-2858-2482
dc.authorid Kaplan, Muammer/0000-0002-8312-5479
dc.authorid Capanoglu, Esra/0000-0003-0335-9433
dc.authorscopusid 55628003500
dc.authorscopusid 57202497708
dc.authorscopusid 57194272564
dc.authorscopusid 7403264862
dc.authorscopusid 56166763900
dc.authorscopusid 23666338900
dc.authorwosid Ozdal, Tugba/B-5799-2018
dc.authorwosid Ceylan, Fatma Duygu/AAA-2588-2020
dc.authorwosid Kaplan, Muammer/I-2261-2019
dc.authorwosid Capanoglu, Esra/A-4455-2018
dc.contributor.author Ozdal, Tugba
dc.contributor.author Ceylan, Fatma Duygu
dc.contributor.author Eroglu, Nazife
dc.contributor.author Kaplan, Muammer
dc.contributor.author Olgun, Elmas Oktem
dc.contributor.author Capanoglu, Esra
dc.date.accessioned 2024-05-25T11:41:16Z
dc.date.available 2024-05-25T11:41:16Z
dc.date.issued 2019
dc.department Okan University en_US
dc.department-temp [Ozdal, Tugba] Istanbul Okan Univ, Fac Engn, Dept Food Engn, TR-34959 Istanbul, Turkey; [Ceylan, Fatma Duygu; Capanoglu, Esra] Istanbul Tech Univ, Fac Chem & Met Engn, Dept Food Engn, TR-34469 Istanbul, Turkey; [Eroglu, Nazife; Kaplan, Muammer] TUBITAK Marmara Res Ctr, Inst Chem Technol, TR-41470 Kocaeli, Turkey; [Olgun, Elmas Oktem] TUBITAK Marmara Res Ctr, Environm & Cleaner Prod Inst, TR-41470 Kocaeli, Turkey; [Eroglu, Nazife] ALCON, Vis Care R&D, 11460 Johns Creek Pkwy, Duluth, GA 30097 USA en_US
dc.description Ozdal, Tugba/0000-0001-8344-5336; Ceylan, Fatma Duygu/0000-0002-2858-2482; Kaplan, Muammer/0000-0002-8312-5479; Capanoglu, Esra/0000-0003-0335-9433 en_US
dc.description.abstract Propolis is a resinous bee hive product that has many biological activities. In this study, a total of 11 raw propolis samples were collected from various geographical areas in Turkey. Phenolic compounds were extracted from all samples and analyses of total phenolics and flavonoids and total antioxidant capacities were performed. All the samples showed high total phenolic and flavonoid contents and antioxidant capacities. Moreover, the in vitro bioaccessibility of Turkish propolis samples were investigated according to simulated in vitro gastrointestinal digestion method. Bioaccessibility was increased through the gastric and intestinal phases. Furthermore, the composition of polyphenols (phenolic acids and flavonoids) in Turkish propolis extracts was investigated by LC-MS/MS method. A total of 32 phenolic compounds, including Caffeic acid phenylethyl ester (CAPE) which was observed in all samples, were identified in the samples. Higher CAPE contents were determined in the samples from the Marmara region which is in line with its higher antioxidant capacity values. As a conclusion, propolis samples collected from different geographical locations differ for their phenolic and flavonoid contents, individual phenolic profile and bioaccessibility. en_US
dc.description.sponsorship Scientific and Technological Research Council of Turkey (TUBITAK), BIDEB-2232 Project [113C036, 5134103] en_US
dc.description.sponsorship This study was fully supported by the Scientific and Technological Research Council of Turkey (TUBITAK), BIDEB-2232 Project No: 113C036, Institution Code: 5134103 under the name of "Investigation of important honeybee, Apis mellifera L. (Hymenoptera, Apidae), subspecies and ecotypes in Turkey considering propolis collection capacity and chemical characterization of Turkish propolis. en_US
dc.identifier.citationcount 67
dc.identifier.doi 10.1016/j.foodres.2019.05.028
dc.identifier.endpage 536 en_US
dc.identifier.issn 0963-9969
dc.identifier.issn 1873-7145
dc.identifier.pmid 31229108
dc.identifier.scopus 2-s2.0-85066126064
dc.identifier.scopusquality Q1
dc.identifier.startpage 528 en_US
dc.identifier.uri https://doi.org/10.1016/j.foodres.2019.05.028
dc.identifier.uri https://hdl.handle.net/20.500.14517/1504
dc.identifier.volume 122 en_US
dc.identifier.wos WOS:000473379200055
dc.identifier.wosquality Q1
dc.language.iso en
dc.publisher Elsevier en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.scopus.citedbyCount 89
dc.subject Propolis en_US
dc.subject Phenolic compounds en_US
dc.subject Antioxidant capacity en_US
dc.subject In vitro gastrointestinal digestion en_US
dc.subject Bioaccessibility en_US
dc.subject LC-MS/MS en_US
dc.title Investigation of antioxidant capacity, bioaccessibility and LC-MS/MS phenolic profile of Turkish propolis en_US
dc.type Article en_US
dc.wos.citedbyCount 79

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