Malignancy in patients with sarcoidosis

dc.authorid KOBAK, SENOL/0000-0001-8270-640X
dc.authorscopusid 12782228700
dc.authorscopusid 57195398766
dc.authorscopusid 57006709600
dc.authorscopusid 6701401491
dc.authorwosid KOBAK, SENOL/AAO-2482-2020
dc.authorwosid orman, mehmet/JUU-4618-2023
dc.contributor.author Kobak, Senol
dc.contributor.author Yildiz, Fidan
dc.contributor.author Semiz, Huseyin
dc.contributor.author Orman, Mehmet
dc.date.accessioned 2024-05-25T11:42:17Z
dc.date.available 2024-05-25T11:42:17Z
dc.date.issued 2021
dc.department Okan University en_US
dc.department-temp [Kobak, Senol] Istinye Univ, LIV Hosp, Fac Med, Dept Rheumatol, Istanbul, Turkey; [Yildiz, Fidan] Okan Univ, Fac Med, Dept Chest Dis, Istanbul, Turkey; [Semiz, Huseyin] Ege Univ, Fac Med, Dept Internal Med, Bornova, Turkey; [Orman, Mehmet] Ege Univ, Fac Med, Dept Stat, Bornova, Turkey en_US
dc.description KOBAK, SENOL/0000-0001-8270-640X; en_US
dc.description.abstract The relationship between sarcoidosis and malignancy is not clear yet. We retrospectively evaluated 131 sarcoidosis patients followed-up at the single Rheumatology center. The incidence of malignancies was investigated in this cohort. A total of 6 (4.6%) patients with malignancy were identified in our cohort of 131 patients with sarcoidosis. Hodgkin lymphoma (HL) was detected in three patients, followed by one patient with breast cancer, one patient with thyroid cancer and one patient with testicular cancer. All patients had chronic sarcoidosis with pulmonary involvement, and only 1 patient had acute sarcoidosis with Lofgren's syndrome. HL developed concomitantly with sarcoidosis in one patient while other two patients developed disease before and after sarcoidosis diagnosis. Two patients with solid tumors developed malignancy years before sarcoidosis diagnosis, while one patient developed thyroid cancer during sarcoidosis follow-up. All 6 sarcoidosis-malignancy patients survived after six year years follow up. We found low incidence of malignancy in patients with sarcoidosis in our small cohort. The sarcoidosis-malignancy relationship can only be a coincidence and/or can be explained by a common pathogenesis. New prospective studies involving large patients series are needed in this regard. (C) 2019 Elsevier Espafia, S.L.U. and Sociedad Espafiola de Reumatologia y Colegio Mexicano de Reumatologia. All rights reserved. en_US
dc.identifier.citationcount 7
dc.identifier.doi 10.1016/j.reuma.2019.04.003
dc.identifier.endpage 51 en_US
dc.identifier.issn 1699-258X
dc.identifier.issn 1885-1398
dc.identifier.issue 1 en_US
dc.identifier.pmid 31153889
dc.identifier.scopus 2-s2.0-85066129328
dc.identifier.scopusquality Q3
dc.identifier.startpage 49 en_US
dc.identifier.uri https://doi.org/10.1016/j.reuma.2019.04.003
dc.identifier.uri https://hdl.handle.net/20.500.14517/1572
dc.identifier.volume 17 en_US
dc.identifier.wos WOS:000608393600010
dc.language.iso en
dc.publisher Elsevier Espana Slu en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.scopus.citedbyCount 6
dc.subject Sarcoidosis en_US
dc.subject Malignidad en_US
dc.subject Incidencia en_US
dc.title Malignancy in patients with sarcoidosis en_US
dc.type Article en_US
dc.wos.citedbyCount 8

Files