The impact of Ramadan fasting on oxidative stress levels in the second trimester of pregnancy

dc.authorscopusid 56548526700
dc.authorscopusid 57209730750
dc.authorscopusid 58250298000
dc.authorscopusid 57225978331
dc.authorscopusid 59218361000
dc.authorscopusid 55984973000
dc.authorscopusid 55984973000
dc.contributor.author Kasap, Esin
dc.contributor.author Torun, Raziye
dc.contributor.author Kardesler, Sema
dc.contributor.author Gorgulu, Goeksen
dc.contributor.author Bozgeyik, M. Bora
dc.contributor.author Guzel, Yilmaz
dc.contributor.author Gulec, Ebru Sahin
dc.date.accessioned 2024-10-15T20:18:09Z
dc.date.available 2024-10-15T20:18:09Z
dc.date.issued 2024
dc.department Okan University en_US
dc.department-temp [Kasap, Esin; Bozgeyik, M. Bora; Gulec, Ebru Sahin] Univ Hlth Sci, Tepecik Educ & Res Hosp, Dept Obstet & Gynecol, Izmir, Turkiye; [Torun, Raziye] Univ Hlth Sci, Tepecik Educ & Res Hosp, Dept Perinatol, Izmir, Turkiye; [Kardesler, Sema] Univ Hlth Sci, Tepecik Educ & Res Hosp, Dept Med Biochem, Izmir, Turkiye; [Gorgulu, Goeksen] Univ Hlth Sci, Tepecik Educ & Res Hosp, Dept Gynecol Oncol, Izmir, Turkiye; [Guzel, Yilmaz] Okan Univ, Dept Obstet & Gynecol, Istanbul, Turkiye en_US
dc.description.abstract Background: The primary objective of this study was to assess the effect of fasting during Ramadan on maternal oxidative stress levels and foetal development; pregnant women with uncomplicated, singleton pregnancies in the second trimester. Methods: During the month of Ramadan, 23 March 2023 to 20 April 2023, 50 fasting and 50 non-fasting healthy pregnant women were enrolled in this prospective study. The fasting hours were about 14 h per day in that season. Pregnant women in the second trimester were enrolled in the study. Total antioxidant status (TAS), total oxidant status (TOS) and the oxidative stress index (OSI) were measured from maternal serum samples taken on a fasting day at the end of Ramadan. To evaluate the impact of Ramadan on the foetus, Doppler ultrasonography was performed in the beginning and then at the end of Ramadan in all participants and was used for the following measurements: Increase of biparietal diameter, femur length, estimated foetal body weight, amniotic fluid index and umbilical artery systolic/diastolic ratio. To discern differences between distinct cohorts, independent t-tests and Mann-Whitney's U-tests were employed based on the data distribution. A p value threshold of less than .05 was established to determine statistical significance. Results: TAS level was found to be significantly lower in the group that fasted for more than 15 days compared to the non-fasting group that did not fast (p = .003), but no significant differences were found between the groups in terms of TOS and OSI (p < .05). Obstetric ultrasound parameters showed no significant differences between the two groups (p < .05). Conclusions: The present study suggests that fasting during the second trimester of pregnancy does not substantially impact maternal or foetal health, as indicated by most oxidative stress markers and foetal parameters studied. However, the observed reduction in the TAS levels in the fasting group warrants further investigation. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.citationcount 0
dc.identifier.doi 10.1080/01443615.2024.2408690
dc.identifier.issn 0144-3615
dc.identifier.issn 1364-6893
dc.identifier.issue 1 en_US
dc.identifier.pmid 39329321
dc.identifier.scopus 2-s2.0-85205152201
dc.identifier.scopusquality Q3
dc.identifier.uri https://doi.org/10.1080/01443615.2024.2408690
dc.identifier.uri https://hdl.handle.net/20.500.14517/6343
dc.identifier.volume 44 en_US
dc.identifier.wos WOS:001321625600001
dc.identifier.wosquality Q4
dc.language.iso en
dc.publisher Taylor & Francis inc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.scopus.citedbyCount 0
dc.subject Foetal development en_US
dc.subject oxidative stress en_US
dc.subject pregnancy en_US
dc.subject Ramadan fasting en_US
dc.title The impact of Ramadan fasting on oxidative stress levels in the second trimester of pregnancy en_US
dc.type Article en_US
dc.wos.citedbyCount 0

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