Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction

dc.authorid Karagün, Ebru/0000-0002-5032-7429
dc.authorid ELLIBES KAYA, ASKI/0000-0002-1323-7416
dc.authorid Caliskan, Eray/0000-0002-6799-5909
dc.authorscopusid 57194603875
dc.authorscopusid 55259746600
dc.authorscopusid 55587304900
dc.authorscopusid 6701507807
dc.authorwosid Karagün, Ebru/ABB-7919-2020
dc.authorwosid Caliskan, Eray/HTR-8541-2023
dc.contributor.author Sukgen, Gokmen
dc.contributor.author Kaya, Aski Ellibes
dc.contributor.author Karagun, Ebru
dc.contributor.author Caliskan, Eray
dc.date.accessioned 2024-05-25T11:39:26Z
dc.date.available 2024-05-25T11:39:26Z
dc.date.issued 2019
dc.department Okan University en_US
dc.department-temp [Sukgen, Gokmen] Private Practice Clin, Clin Obstet & Gynecol, Adana, Turkey; [Kaya, Aski Ellibes] Duzce Univ, Fac Med, Dept Obstet & Gynecol, Duzce, Turkey; [Karagun, Ebru] Duzce Univ, Fac Med, Dept Dermatol, Duzce, Turkey; [Caliskan, Eray] Okan Univ, Fac Med, Dept Obstet & Gynecol, Istanbul, Turkey en_US
dc.description Karagün, Ebru/0000-0002-5032-7429; ELLIBES KAYA, ASKI/0000-0002-1323-7416; Caliskan, Eray/0000-0002-6799-5909 en_US
dc.description.abstract Objective: To investigate the effect of platelet-rich plasma (PRP) injection to the lower one-third of the anterior vaginal wall on sexual function, orgasm, and genital perception in women with sexual dysfunction. Materials and Methods: Four sessions of PRP were administered to the anterior vaginal wall of 52 female patients with sexual dysfunction and orgasmic disorder [Female Sexual Function Index (FSFI) total score <= 26 orgasmic subdomain score <= 3.75]. Prior to the PRP administrations in each session, the FSFI validated in Turkish, the Female Genital Self-Image Scale (FGSIS), the Female Sexual Distress Scale-Revised (FSDS-R), and Rosenberg's Self-Esteem Scale were used and in the final follow-up, and the Patient Global Impression of Improvement (PGI-I) was performed and the results were analyzed. Results: Following the application of the PRP, the total FSFI score was observed as 27.88 +/- 4.80 and the total score was 26 and above in 50% of the patients (p<0.001). Orgasm subdomain scores were found as 2.11 +/- 1.20 before the PRP treatment and 4.48 +/- 1.14 afterwards (p<0.001). A significant change was observed in all sub-domains after PRP and it was observed that this change started after the first administration (p<0.001). A statistically significant increase was determined in FGSIS genital perception scores, which was significant between the and 2nd months (p<0.001). The FSDS-R scores showed a minimal increase in stress scores as the application number increased, but a statistically significant decrease was observed in the 4th administration (p<0.001). No statistically significant difference was found in Rosenberg Scale scores before and after treatment (p=0.389). High satisfaction was found in PGI-I scores. Conclusion: As a minimally invasive method, PRP administration to the distal anterior vaginal wall may improve female sexuality with high satisfaction. en_US
dc.identifier.citationcount 12
dc.identifier.doi 10.4274/tjod.galenos.2019.23356
dc.identifier.endpage 234 en_US
dc.identifier.issn 2149-9322
dc.identifier.issn 2149-9330
dc.identifier.issue 4 en_US
dc.identifier.pmid 32231853
dc.identifier.scopus 2-s2.0-85089448507
dc.identifier.scopusquality Q3
dc.identifier.startpage 228 en_US
dc.identifier.trdizinid 371057
dc.identifier.uri https://doi.org/10.4274/tjod.galenos.2019.23356
dc.identifier.uri https://hdl.handle.net/20.500.14517/1352
dc.identifier.volume 16 en_US
dc.identifier.wos WOS:000518406200006
dc.language.iso en
dc.publisher Galenos Yayincilik en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.scopus.citedbyCount 22
dc.subject Platelet-rich plasma en_US
dc.subject female sexual dysfunction en_US
dc.subject female orgasmic disorder en_US
dc.title Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction en_US
dc.type Article en_US
dc.wos.citedbyCount 15

Files